Akira Takashima spends much of his time researching Immunology, Molecular biology, Cell biology, Dendritic cell and Antigen presentation. His work is dedicated to discovering how Immunology, Cytotoxic T cell are connected with Programmed cell death, Fas receptor and Apoptosis and other disciplines. His studies deal with areas such as Tumor necrosis factor alpha, Glycosaminoglycan, Peptide sequence, Gene and Monoclonal antibody as well as Molecular biology.
His biological study spans a wide range of topics, including Internal medicine and Endocrinology. His work carried out in the field of Dendritic cell brings together such families of science as T cell, CD86, Antigen-presenting cell and CD40. The various areas that Akira Takashima examines in his Antigen presentation study include MHC class II and CD11c.
His primary areas of study are Cell biology, Immunology, Dendritic cell, Molecular biology and Immune system. His studies in Cell biology integrate themes in fields like Cell culture, Keratinocyte, Cytokine and T cell. Akira Takashima interconnects Receptor, Clone, Cellular differentiation and Antigen-presenting cell in the investigation of issues within Dendritic cell.
His work deals with themes such as In vitro, Gene expression, Gene, T-cell receptor and Antibody, which intersect with Molecular biology. He has included themes like Transfection and In vivo in his Immune system study. His Epidermis research is multidisciplinary, relying on both Dermis and Messenger RNA.
His scientific interests lie mostly in Immunology, Cell biology, Dendritic cell, Immune system and Antigen-presenting cell. His studies deal with areas such as Phenotype and In vivo as well as Immunology. He works in the field of Cell biology, namely Epidermis.
In his research on the topic of Dendritic cell, Biological activity, T cell, Sensitization and Allergic contact dermatitis is strongly related with Clone. His Immune system research incorporates themes from Cellular differentiation and Antigen. His Antigen-presenting cell study combines topics from a wide range of disciplines, such as Cancer research, Neutrophil extracellular traps, CD11c, Cell Maturation and CD80.
His main research concerns Immunology, Antigen-presenting cell, Immune system, Dendritic cell and Innate immune system. The concepts of his Immunology study are interwoven with issues in Heparin-binding EGF-like growth factor, Green fluorescent protein, Confocal microscopy, Cell biology and In vivo. His Antigen-presenting cell study integrates concerns from other disciplines, such as Antigen presentation, Neutrophil extracellular traps and CD11c.
His research integrates issues of Cellular differentiation and Antigen in his study of Immune system. His Dendritic cell research includes elements of Inflammation, CD86, Cancer research and CD80. Akira Takashima focuses mostly in the field of Innate immune system, narrowing it down to matters related to Microbiology and, in some cases, Acyloxyacyl hydrolase, Lipopolysaccharide, B cell and Antibody.
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Identification of a novel, dendritic cell-associated molecule, dectin-1, by subtractive cDNA cloning.
Kiyoshi Ariizumi;Guo Liang Shen;Sojin Shikano;Shan Xu.
Journal of Biological Chemistry (2000)
CD39 is the dominant Langerhans cell–associated ecto-NTPDase: Modulatory roles in inflammation and immune responsiveness
Norikatsu Mizumoto;Tadashi Kumamoto;Simon C. Robson;Jean Sévigny.
Nature Medicine (2002)
Generation and function of reactive oxygen species in dendritic cells during antigen presentation.
Hiroyuki Matsue;Dale Edelbaum;David Shalhevet;Norikatsu Mizumoto.
Journal of Immunology (2003)
Cloning and characterization of the 2B4 gene encoding a molecule associated with non-MHC-restricted killing mediated by activated natural killer cells and T cells.
P. A. Mathew;B. A. Garni-Wagner;K. Land;A. Takashima.
Journal of Immunology (1993)
Regulation of T-cell receptor γ-chain RNA expression in murine Thy-1+ dendritic epidermal cells
William A. Kuziel;Akira Takashima;Mark Bonyhadi;Paul R. Bergstresser.
Development of a Peptide Inhibitor of Hyaluronan-Mediated Leukocyte Trafficking
Mark E. Mummert;Mansour Mohamadzadeh;Diana I. Mummert;Norikatsu Mizumoto.
Journal of Experimental Medicine (2000)
A role for NF-κB–dependent gene transactivation in sunburn
Kazuhiro Abeyama;William Eng;James V. Jester;Arie A. Vink.
Journal of Clinical Investigation (2000)
Cloning of a Second Dendritic Cell-associated C-type Lectin (Dectin-2) and Its Alternatively Spliced Isoforms
Kiyoshi Ariizumi;Guo Liang Shen;Sojin Shikano;Robert Ritter.
Journal of Biological Chemistry (2000)
Induction of antigen-specific immunosuppression by CD95L cDNA-transfected 'killer' dendritic cells.
Hiroyuki Matsue;Keiko Matsue;Michael Walters;Ko Okumura.
Nature Medicine (1999)
Neutrophil-derived IL-1β Is Sufficient for Abscess Formation in Immunity against Staphylococcus aureus in Mice
John S. Cho;Yi Guo;Romela Irene Ramos;Frank Hebroni.
PLOS Pathogens (2012)
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