H-Index & Metrics Best Publications

H-Index & Metrics

Discipline name H-index Citations Publications World Ranking National Ranking
Immunology D-index 49 Citations 7,405 103 World Ranking 2817 National Ranking 1338

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Immune system
  • Cytokine

Akira Takashima spends much of his time researching Immunology, Molecular biology, Cell biology, Dendritic cell and Antigen presentation. His work is dedicated to discovering how Immunology, Cytotoxic T cell are connected with Programmed cell death, Fas receptor and Apoptosis and other disciplines. His studies deal with areas such as Tumor necrosis factor alpha, Glycosaminoglycan, Peptide sequence, Gene and Monoclonal antibody as well as Molecular biology.

His biological study spans a wide range of topics, including Internal medicine and Endocrinology. His work carried out in the field of Dendritic cell brings together such families of science as T cell, CD86, Antigen-presenting cell and CD40. The various areas that Akira Takashima examines in his Antigen presentation study include MHC class II and CD11c.

His most cited work include:

  • Identification of a novel, dendritic cell-associated molecule, dectin-1, by subtractive cDNA cloning. (386 citations)
  • CD39 is the dominant Langerhans cell–associated ecto-NTPDase: Modulatory roles in inflammation and immune responsiveness (269 citations)
  • Generation and function of reactive oxygen species in dendritic cells during antigen presentation. (205 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of study are Cell biology, Immunology, Dendritic cell, Molecular biology and Immune system. His studies in Cell biology integrate themes in fields like Cell culture, Keratinocyte, Cytokine and T cell. Akira Takashima interconnects Receptor, Clone, Cellular differentiation and Antigen-presenting cell in the investigation of issues within Dendritic cell.

His work deals with themes such as In vitro, Gene expression, Gene, T-cell receptor and Antibody, which intersect with Molecular biology. He has included themes like Transfection and In vivo in his Immune system study. His Epidermis research is multidisciplinary, relying on both Dermis and Messenger RNA.

He most often published in these fields:

  • Cell biology (45.23%)
  • Immunology (35.68%)
  • Dendritic cell (31.16%)

What were the highlights of his more recent work (between 2004-2016)?

  • Immunology (35.68%)
  • Cell biology (45.23%)
  • Dendritic cell (31.16%)

In recent papers he was focusing on the following fields of study:

His scientific interests lie mostly in Immunology, Cell biology, Dendritic cell, Immune system and Antigen-presenting cell. His studies deal with areas such as Phenotype and In vivo as well as Immunology. He works in the field of Cell biology, namely Epidermis.

In his research on the topic of Dendritic cell, Biological activity, T cell, Sensitization and Allergic contact dermatitis is strongly related with Clone. His Immune system research incorporates themes from Cellular differentiation and Antigen. His Antigen-presenting cell study combines topics from a wide range of disciplines, such as Cancer research, Neutrophil extracellular traps, CD11c, Cell Maturation and CD80.

Between 2004 and 2016, his most popular works were:

  • Neutrophil-derived IL-1β Is Sufficient for Abscess Formation in Immunity against Staphylococcus aureus in Mice (150 citations)
  • Neutrophil differentiation into a unique hybrid population exhibiting dual phenotype and functionality of neutrophils and dendritic cells. (112 citations)
  • Classification of Chemotherapeutic Agents Based on Their Differential In vitro Effects on Dendritic Cells (97 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Immune system
  • Cytokine

His main research concerns Immunology, Antigen-presenting cell, Immune system, Dendritic cell and Innate immune system. The concepts of his Immunology study are interwoven with issues in Heparin-binding EGF-like growth factor, Green fluorescent protein, Confocal microscopy, Cell biology and In vivo. His Antigen-presenting cell study integrates concerns from other disciplines, such as Antigen presentation, Neutrophil extracellular traps and CD11c.

His research integrates issues of Cellular differentiation and Antigen in his study of Immune system. His Dendritic cell research includes elements of Inflammation, CD86, Cancer research and CD80. Akira Takashima focuses mostly in the field of Innate immune system, narrowing it down to matters related to Microbiology and, in some cases, Acyloxyacyl hydrolase, Lipopolysaccharide, B cell and Antibody.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Identification of a novel, dendritic cell-associated molecule, dectin-1, by subtractive cDNA cloning.

Kiyoshi Ariizumi;Guo Liang Shen;Sojin Shikano;Shan Xu.
Journal of Biological Chemistry (2000)

598 Citations

CD39 is the dominant Langerhans cell–associated ecto-NTPDase: Modulatory roles in inflammation and immune responsiveness

Norikatsu Mizumoto;Tadashi Kumamoto;Simon C. Robson;Jean Sévigny.
Nature Medicine (2002)

361 Citations

Cloning and characterization of the 2B4 gene encoding a molecule associated with non-MHC-restricted killing mediated by activated natural killer cells and T cells.

P. A. Mathew;B. A. Garni-Wagner;K. Land;A. Takashima.
Journal of Immunology (1993)

310 Citations

Generation and function of reactive oxygen species in dendritic cells during antigen presentation.

Hiroyuki Matsue;Dale Edelbaum;David Shalhevet;Norikatsu Mizumoto.
Journal of Immunology (2003)

307 Citations

Regulation of T-cell receptor γ-chain RNA expression in murine Thy-1+ dendritic epidermal cells

William A. Kuziel;Akira Takashima;Mark Bonyhadi;Paul R. Bergstresser.
Nature (1987)

271 Citations

A role for NF-κB–dependent gene transactivation in sunburn

Kazuhiro Abeyama;William Eng;James V. Jester;Arie A. Vink.
Journal of Clinical Investigation (2000)

229 Citations

Cloning of a Second Dendritic Cell-associated C-type Lectin (Dectin-2) and Its Alternatively Spliced Isoforms

Kiyoshi Ariizumi;Guo Liang Shen;Sojin Shikano;Robert Ritter.
Journal of Biological Chemistry (2000)

229 Citations

Induction of antigen-specific immunosuppression by CD95L cDNA-transfected 'killer' dendritic cells.

Hiroyuki Matsue;Keiko Matsue;Michael Walters;Ko Okumura.
Nature Medicine (1999)

228 Citations

Development of a Peptide Inhibitor of Hyaluronan-Mediated Leukocyte Trafficking

Mark E. Mummert;Mansour Mohamadzadeh;Diana I. Mummert;Norikatsu Mizumoto.
Journal of Experimental Medicine (2000)

225 Citations

Successive generation of antigen-presenting, dendritic cell lines from murine epidermis.

Shan Xu;K. Ariizumi;G. Caceres-Dittmar;D. Edelbaum.
Journal of Immunology (1995)

214 Citations

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