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Tetsuo Takehara

Tetsuo Takehara

D-Index & Metrics

Medicine

D-Index
84
Citations
26806
World Ranking
15057
National Ranking
461

Overview

Tetsuo Takehara is affiliated with Osaka University in Japan and specializes in medical research with a focus on hepatology. Over their career, Takehara has contributed extensively to the understanding of liver diseases, their diagnosis, and treatment, with an emphasis on hepatocellular carcinoma and liver cirrhosis.

Their recent publications include significant contributions to clinical guidelines and the pathology of liver diseases. Notable papers are:

  • Management of Hepatocellular Carcinoma in Japan: JSH Consensus Statements and Recommendations 2021 Update (2021, Liver Cancer)
  • Evidence-based clinical practice guidelines for Liver Cirrhosis 2020 (2021, Journal of Gastroenterology)
  • Evidence-based clinical practice guidelines for nonalcoholic fatty liver disease/nonalcoholic steatohepatitis 2020 (2021, Journal of Gastroenterology)
  • Hepatic Stellate Cells in Hepatocellular Carcinoma Promote Tumor Growth Via Growth Differentiation Factor 15 Production (2020, Gastroenterology)
  • Evidence-based clinical practice guidelines for liver cirrhosis 2020 (2021, Hepatology Research)

Frequent collaborators of Takehara include:

  • Hayato Hikita
  • Takahiro Kodama
  • Tomohide Tatsumi
  • Ryotaro Sakamori
  • Yoshito Hayashi

Takehara's work is often published in prominent journals, indicating a focus on both clinical and research aspects of hepatology and gastroenterology. The most common publication venues for their work include:

  • Journal of Gastroenterology
  • Hepatology Research
  • Journal of Gastroenterology and Hepatology
  • Gastroenterology
  • Scientific Reports

The main field of study for Takehara is Medicine, with 480 documented publications. Within this broad field, their research extensively covers subfields such as:

  • Hepatology
  • Epidemiology
  • Surgery
  • Pulmonary and Respiratory Medicine
  • Oncology

Their primary research topics reflect this specialization in liver and related diseases and include:

  • Liver Disease Diagnosis and Treatment
  • Hepatitis C virus research
  • Gastric Cancer Management and Outcomes
  • Liver Disease and Transplantation
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Hepatitis B Virus Studies
  • Inflammatory Bowel Disease

Best Publications

  • Daclatasvir plus asunaprevir for chronic HCV genotype 1b infection.

    Hiromitsu Kumada;Yoshiyuki Suzuki;Kenji Ikeda;Joji Toyota

  • Evidence-based clinical practice guidelines for nonalcoholic fatty liver disease/nonalcoholic steatohepatitis*

    Sumio Watanabe;Etsuko Hashimoto;Kenichi Ikejima;Hirofumi Uto

  • Quantitative analysis of hepatitis C virus RNA in serum during interferon alfa therapy.

    Hideki Hagiwara;Norio Hayashi;Eiji Mita;Tetsuo Takehara

  • Ledipasvir and sofosbuvir fixed-dose combination with and without ribavirin for 12 weeks in treatment-naive and previously treated Japanese patients with genotype 1 hepatitis C: an open-label, randomised, phase 3 trial.

    Masashi Mizokami;Osamu Yokosuka;Tetsuo Takehara;Naoya Sakamoto

  • Impaired Allostimulatory Capacity of Peripheral Blood Dendritic Cells Recovered from Hepatitis C Virus-Infected Individuals

    Tatsuya Kanto;Norio Hayashi;Tetsuo Takehara;Tomohide Tatsumi

  • The let-7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma

    Satoshi Shimizu;Tetsuo Takehara;Hayato Hikita;Takahiro Kodama

  • Management of Hepatocellular Carcinoma in Japan: JSH Consensus Statements and Recommendations 2021 Update.

    Masatoshi Kudo;Yusuke Kawamura;Kiyoshi Hasegawa;Ryosuke Tateishi

  • Evidence-based clinical practice guidelines for Liver Cirrhosis 2020

    Hitoshi Yoshiji;Sumiko Nagoshi;Takemi Akahane;Yoshinari Asaoka

  • Critical Role of MHC Class I-Related Chain A and B Expression on IFN-α-Stimulated Dendritic Cells in NK Cell Activation: Impairment in Chronic Hepatitis C Virus Infection

    Masahisa Jinushi;Tetsuo Takehara;Tatsuya Kanto;Tomohide Tatsumi

  • Rubicon inhibits autophagy and accelerates hepatocyte apoptosis and lipid accumulation in nonalcoholic fatty liver disease in mice.

    Satoshi Tanaka;Hayato Hikita;Tomohide Tatsumi;Ryotaro Sakamori

  • Expression and role of Bcl-xL in human hepatocellular carcinomas.

    Tetsuo Takehara;Tetsuo Takehara;Xiaolong Liu;Jiro Fujimoto;Scott L. Friedman

  • Expression and role of MICA and MICB in human hepatocellular carcinomas and their regulation by retinoic acid.

    Masahisa Jinushi;Tetsuo Takehara;Tomohide Tatsumi;Tatsuya Kanto

  • Negative Regulation of NK Cell Activities by Inhibitory Receptor CD94/NKG2A Leads to Altered NK Cell-Induced Modulation of Dendritic Cell Functions in Chronic Hepatitis C Virus Infection

    Masahisa Jinushi;Tetsuo Takehara;Tomohide Tatsumi;Tatsuya Kanto

  • Scheduled endoscopic surveillance controls secondary cancer after curative endoscopic resection for early gastric cancer: a multicentre retrospective cohort study by Osaka University ESD study group

    Motohiko Kato;Tsutomu Nishida;Katsumi Yamamoto;Shiro Hayashi

  • Inhibition of autophagy potentiates the antitumor effect of the multikinase inhibitor sorafenib in hepatocellular carcinoma.

    Satoshi Shimizu;Tetsuo Takehara;Hayato Hikita;Takahiro Kodama

  • Impairment of natural killer cell and dendritic cell functions by the soluble form of MHC class I-related chain A in advanced human hepatocellular carcinomas.

    Masahisa Jinushi;Tetsuo Takehara;Tomohide Tatsumi;Naoki Hiramatsu

  • Hepatocyte-specific disruption of Bcl-xL leads to continuous hepatocyte apoptosis and liver fibrotic responses

    Tetsuo Takehara;Tomohide Tatsumi;Takahiro Suzuki;Edmund B. Rucker

  • Detection of hepatitis C virus RNA in serum of patients with chronic hepatitis C treated with interferon-α

    Hideki Hagiwara;Norio Hayashi;Eiji Mita;Keiji Ueda

  • Cytoplasmic STAT3 represses autophagy by inhibiting PKR activity.

    Shensi Shen;Mireia Niso-Santano;Mireia Niso-Santano;Mireia Niso-Santano;Sandy Adjemian;Sandy Adjemian;Sandy Adjemian;Tetsuo Takehara

  • Reduced Numbers and Impaired Ability of Myeloid and Plasmacytoid Dendritic Cells to Polarize T Helper Cells in Chronic Hepatitis C Virus Infection

    Tatsuya Kanto;Michiyo Inoue;Hideki Miyatake;Aki Sato

Frequent Co-Authors

Norio Hayashi
Norio Hayashi Osaka University
Tatsuya Kanto
Tatsuya Kanto Osaka University
Eiji Miyoshi
Eiji Miyoshi Osaka University
Eiichi Morii
Eiichi Morii Osaka University
Takenobu Kamada
Takenobu Kamada Osaka University
Kazuaki Chayama
Kazuaki Chayama Hiroshima University
Masatsugu Hori
Masatsugu Hori Osaka University
Yuichiro Doki
Yuichiro Doki Osaka University
Hidetoshi Eguchi
Hidetoshi Eguchi Osaka University
Namiki Izumi
Namiki Izumi Musashino Red Cross Hospital

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