Tatsuya Kanto

Best Publications

• Impaired Allostimulatory Capacity of Peripheral Blood Dendritic Cells Recovered from Hepatitis C Virus-Infected Individuals

  Tatsuya Kanto;Norio Hayashi;Tetsuo Takehara;Tomohide Tatsumi

  456
  Citations

• Circulating microRNA-21 as a novel biomarker for hepatocellular carcinoma.

  Yoshito Tomimaru;Hidetoshi Eguchi;Hiroaki Nagano;Hiroshi Wada

  443
  Citations

• Critical Role of MHC Class I-Related Chain A and B Expression on IFN-α-Stimulated Dendritic Cells in NK Cell Activation: Impairment in Chronic Hepatitis C Virus Infection

  Masahisa Jinushi;Tetsuo Takehara;Tatsuya Kanto;Tomohide Tatsumi

  344
  Citations

• Expression and role of MICA and MICB in human hepatocellular carcinomas and their regulation by retinoic acid.

  Masahisa Jinushi;Tetsuo Takehara;Tomohide Tatsumi;Tatsuya Kanto

  317
  Citations

• Negative Regulation of NK Cell Activities by Inhibitory Receptor CD94/NKG2A Leads to Altered NK Cell-Induced Modulation of Dendritic Cell Functions in Chronic Hepatitis C Virus Infection

  Masahisa Jinushi;Tetsuo Takehara;Tomohide Tatsumi;Tatsuya Kanto

  316
  Citations

• Reduced Numbers and Impaired Ability of Myeloid and Plasmacytoid Dendritic Cells to Polarize T Helper Cells in Chronic Hepatitis C Virus Infection

  Tatsuya Kanto;Michiyo Inoue;Hideki Miyatake;Aki Sato

  278
  Citations

• A novel bulk-culture method for generating mature dendritic cells from mouse bone marrow cells.

  Young Ik Son;Shin Ichi Egawa;Tomohide Tatsumi;Richard E. Redlinger

  242
  Citations

• Hepatitis C virus nonstructural protein 5A modulates the toll-like receptor-MyD88-dependent signaling pathway in macrophage cell lines.

  Takayuki Abe;Yuuki Kaname;Itsuki Hamamoto;Yoshimi Tsuda

  226
  Citations

• Autocrine/Paracrine IL-15 That Is Required for Type I IFN-Mediated Dendritic Cell Expression of MHC Class I-Related Chain A and B Is Impaired in Hepatitis C Virus Infection

  Masahisa Jinushi;Tetsuo Takehara;Tomohide Tatsumi;Tatsuya Kanto

  207
  Citations

• Influence of HLA haplotypes on the clinical courses of individuals infected with hepatitis C virus

  Noriyoshi Kuzushita;Norio Hayashi;Toyoki Moribe;Kazuhiro Katayama

  199
  Citations

• The Bcl-xL inhibitor, ABT-737, efficiently induces apoptosis and suppresses growth of hepatoma cells in combination with sorafenib.

  Hayato Hikita;Tetsuo Takehara;Satoshi Shimizu;Takahiro Kodama

  175
  Citations

• Buoyant density of hepatitis C virus recovered from infected hosts : two different features in sucrose equilibrium density-gradient centrifugation related to degree of liver inflammation

  Tatsuya Kanto;Norio Hayashi;Tetsuo Takehara;Hideki Hagiwara

  161
  Citations

• TIE2-expressing monocytes as a diagnostic marker for hepatocellular carcinoma correlates with angiogenesis.

  Tokuhiro Matsubara;Tatsuya Kanto;Shoko Kuroda;Sachiyo Yoshio

  159
  Citations

• Immunopathogenesis of hepatitis C virus infection: multifaceted strategies subverting innate and adaptive immunity.

  Tatsuya Kanto;Norio Hayashi

  146
  Citations

• Expression of costimulatory molecules B7-1 (CD80) and B7-2 (CD86) on human hepatocellular carcinoma

  Tomohide Tatsumi;Tetsuo Takehara;Kazuhiro Katayama;Kiyoshi Mochizuki

  136
  Citations

• Alterations in microRNA expression profile in HCV-infected hepatoma cells: involvement of miR-491 in regulation of HCV replication via the PI3 kinase/Akt pathway.

  Hisashi Ishida;Tomohide Tatsumi;Atsushi Hosui;Takatoshi Nawa

  132
  Citations

• Ceramide mediates tumor-induced dendritic cell apoptosis.

  Tatsuya Kanto;Pawel Kalinski;Oriana C. Hunter;Michael T. Lotze

  128
  Citations

• Human blood dendritic cell antigen 3 (BDCA3)+ dendritic cells are a potent producer of interferon-λ in response to hepatitis C virus

  Sachiyo Yoshio;Tatsuya Kanto;Shoko Kuroda;Tokuhiro Matsubara

  120
  Citations

• Administration of interleukin-12 enhances the therapeutic efficacy of dendritic cell-based tumor vaccines in mouse hepatocellular carcinoma

  Tomohide Tatsumi;Tetsuo Takehara;Tatsuya Kanto;Takuya Miyagi

  120
  Citations

• Safety, Tolerability, and Preliminary Efficacy of the Anti-Fibrotic Small Molecule PRI-724, a CBP/β-Catenin Inhibitor, in Patients with Hepatitis C Virus-related Cirrhosis: A Single-Center, Open-Label, Dose Escalation Phase 1 Trial

  Kiminori Kimura;Akemi Ikoma;Maki Shibakawa;Shinji Shimoda

  120
  Citations