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Biology and Biochemistry

D-Index
60
Citations
10944
World Ranking
12118
National Ranking
5187

Research.com Recognitions

  • 2015 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Janos Zempleni is affiliated with the University of Nebraska-Lincoln in the United States. Their research primarily focuses on biochemistry, genetics, and molecular biology, with a significant emphasis on molecular biology. Additional subfields of study include cancer research, nutrition and dietetics, immunology, and obstetrics and gynecology.

Their work encompasses several main topics, including:

  • Extracellular vesicles in disease
  • MicroRNA in disease regulation
  • Infant nutrition and health
  • RNA interference and gene delivery
  • Reproductive system and pregnancy
  • COVID-19 impact on reproduction
  • Pregnancy and preeclampsia studies

The recent publications authored by Zempleni reflect these research areas and include:

  • Protective Role of Shiitake Mushroom-Derived Exosome-Like Nanoparticles in D-Galactosamine and Lipopolysaccharide-Induced Acute Liver Injury in Mice, 2020, published in Nutrients
  • Milk exosomes and miRNA cross the placenta and promote embryo survival in mice, 2020, published in Reproduction
  • Small Extracellular Vesicles in Milk Cross the Blood-Brain Barrier in Murine Cerebral Cortex Endothelial Cells and Promote Dendritic Complexity in the Hippocampus and Brain Function in C57BL/6J Mice, 2022, published in Frontiers in Nutrition
  • Ruminant Milk-Derived Extracellular Vesicles: A Nutritional and Therapeutic Opportunity?, 2021, published in Nutrients
  • MicroRNAs in bovine milk exosomes are bioavailable in humans but do not elicit a robust pro-inflammatory cytokine response, 2020, published in ExRNA

The venues where Zempleni frequently publishes include:

  • Current Developments in Nutrition
  • American Journal of Physiology-Cell Physiology
  • Extracellular Vesicles and Circulating Nucleic Acids
  • Nutrients
  • Frontiers in Nutrition

Frequent co-authors collaborating with Zempleni include:

  • Juan Cui
  • Alice Ngu
  • Sonal Sukreet
  • Ezra Mutai
  • Haichuan Wang

Zempleni has been recognized as a Fellow of the American Association for the Advancement of Science (AAAS), an honor awarded in 2015.

Best Publications

  • MicroRNAs Are Absorbed in Biologically Meaningful Amounts from Nutritionally Relevant Doses of Cow Milk and Affect Gene Expression in Peripheral Blood Mononuclear Cells, HEK-293 Kidney Cell Cultures, and Mouse Livers

    Scott R. Baier;Christopher Nguyen;Fang Xie;Jennifer R. Wood

  • The Intestinal Transport of Bovine Milk Exosomes Is Mediated by Endocytosis in Human Colon Carcinoma Caco-2 Cells and Rat Small Intestinal IEC-6 Cells

    Tovah Wolf;Scott R Baier;Janos Zempleni

  • Milk exosomes are bioavailable and distinct microRNA cargos have unique tissue distribution patterns

    Sonia Manca;Bijaya Upadhyaya;Ezra Mutai;Amy T. Desaulniers

  • Biological Activities of Extracellular Vesicles and Their Cargos from Bovine and Human Milk in Humans and Implications for Infants

    Janos Zempleni;Ana Aguilar-Lozano;Mahrou Sadri;Sonal Sukreet

  • Pharmacokinetics of orally and intravenously administered riboflavin in healthy humans.

    Janos Zempleni;John R. Galloway;Donald B. McCormick

  • Biotinylation of histones in human cells. Effects of cell proliferation.

    J. Steven Stanley;Jacob B. Griffin;Janos Zempleni

  • UPTAKE, LOCALIZATION, AND NONCARBOXYLASE ROLES OF BIOTIN*

    Janos Zempleni

  • Biotin and biotinidase deficiency

    Janos Zempleni;Yousef I. Hassan;Subhashinee S.K. Wijeratne

  • Regulation of gene expression by biotin☆ (review)

    Rocio Rodriguez-Melendez;Janos Zempleni

  • Human vascular endothelial cells transport foreign exosomes from cow's milk by endocytosis.

    Rio Jati Kusuma;Sonia Manca;Taylor Friemel;Sonal Sukreet

  • Biotin biochemistry and human requirements.

    Janos Zempleni;Donald M. Mock;Donald M. Mock

  • Nutrition, microRNAs, and Human Health.

    Juan Cui;Beiyan Zhou;Sharon A Ross;Janos Zempleni

  • K8 and K12 are biotinylated in human histone H4

    Gabriela Camporeale;Elizabeth E. Shubert;Gautam Sarath;Ronald Cerny

  • Milk-Derived Exosomes and Metabolic Regulation

    Janos Zempleni;Sonal Sukreet;Fang Zhou;Di Wu

  • Epigenetic Regulation of Chromatin Structure and Gene Function by Biotin

    Yousef I. Hassan;Janos Zempleni

  • Roles for nutrients in epigenetic events.

    Anna M. Oommen;Jacob B. Griffin;Gautam Sarath;Janos Zempleni

  • Biotin Supply Affects Expression of Biotin Transporters, Biotinylation of Carboxylases and Metabolism of Interleukin-2 in Jurkat Cells

    Karoline C. Manthey;Jacob B. Griffin;Janos Zempleni

  • Loss of miRNAs during processing and storage of cow's (Bos taurus) milk.

    Katherine M. Howard;Rio Jati Kusuma;Scott R. Baier;Taylor Friemel

  • Uptake and metabolism of biotin by human peripheral blood mononuclear cells

    Janos Zempleni;Donald M. Mock

  • Milk exosomes are bioavailableand distinct microRNA cargos haveunique tissue distribution patterns

    Sonia Manca;Bijaya Upadhyaya;Ezra Mutai;Amy T. Desaulniers

Frequent Co-Authors

Gautam Sarath
Gautam Sarath Agricultural Research Service
Patrick J. Stover
Patrick J. Stover Texas A&M University
Jesse F. Gregory
Jesse F. Gregory University of Florida
Joel C. Eissenberg
Joel C. Eissenberg Saint Louis University
Frank Döring
Frank Döring Kiel University
Stephen D. Cederbaum
Stephen D. Cederbaum University of California, Los Angeles
Hamid M. Said
Hamid M. Said University of California, Irvine
Ronald L. Cerny
Ronald L. Cerny University of Nebraska–Lincoln
John J. McCarthy
John J. McCarthy University of California, Irvine
Kendal D. Hirschi
Kendal D. Hirschi Baylor College of Medicine

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