What is he best known for?
The fields of study he is best known for:
John C. Wallace focuses on Biochemistry, Pyruvate carboxylase, Biotin, Molecular biology and Insulin-like growth factor.
His Biochemistry and Biological activity, Amino acid, Binding protein, Peptide and Plasma protein binding investigations all form part of his Biochemistry research activities.
His Pyruvate carboxylase research includes themes of Mutant, Gene, Saccharomyces cerevisiae, Yeast and Isozyme.
His Biotin research is multidisciplinary, incorporating perspectives in Biotin carboxylase, Cofactor, Stereochemistry and Biotinylation.
His Molecular biology research incorporates elements of Growth factor, Cellular differentiation, Gene expression and Recombinant DNA.
His research in Insulin-like growth factor intersects with topics in Binding domain, Potency, Signal transduction, Cell biology and Affinities.
His most cited work include:
- Development of a Bicistronic Vector Driven by the Human Polypeptide Chain Elongation Factor 1α Promoter for Creation of Stable Mammalian Cell Lines That Express Very High Levels of Recombinant Proteins (251 citations)
- The bovine insulin-like growth factor (IGF) binding protein purified from conditioned medium requires the N-terminal tripeptide in IGF-1 for binding (116 citations)
- Domain Architecture of Pyruvate Carboxylase, a Biotin-Dependent Multifunctional Enzyme (106 citations)
What are the main themes of his work throughout his whole career to date?
His primary scientific interests are in Biochemistry, Pyruvate carboxylase, Molecular biology, Biotin and Enzyme.
His work in Biochemistry tackles topics such as Stereochemistry which are related to areas like Binding site.
His study looks at the relationship between Pyruvate carboxylase and topics such as Acetyl-CoA, which overlap with Methylcrotonyl-CoA carboxylase.
His work in Molecular biology addresses issues such as Saccharomyces cerevisiae, which are connected to fields such as Mutant.
John C. Wallace interconnects Acetyl-CoA carboxylase, Biotin carboxyl carrier protein, Biotinylation and Active site in the investigation of issues within Biotin.
The study incorporates disciplines such as Endocrinology and Internal medicine in addition to Amino acid.
He most often published in these fields:
- Biochemistry (60.18%)
- Pyruvate carboxylase (32.30%)
- Molecular biology (23.45%)
What were the highlights of his more recent work (between 2007-2018)?
- Biochemistry (60.18%)
- Biotin (22.57%)
- Pyruvate carboxylase (32.30%)
In recent papers he was focusing on the following fields of study:
John C. Wallace mainly investigates Biochemistry, Biotin, Pyruvate carboxylase, Molecular biology and DNA ligase.
Biochemistry is frequently linked to Stereochemistry in his study.
His Biotin research integrates issues from Cytoplasm, Biotin carboxyl carrier protein, Biotinylation and Fusion protein.
In Pyruvate carboxylase, John C. Wallace works on issues like Carboxylation, which are connected to Decarboxylation.
His studies in Molecular biology integrate themes in fields like Proximal promoter, Gene and Transcriptional regulation.
His DNA ligase study integrates concerns from other disciplines, such as Acetyl-CoA carboxylase, Repressor and Metabolic pathway.
Between 2007 and 2018, his most popular works were:
- Impaired Anaplerosis and Insulin Secretion in Insulinoma Cells Caused by Small Interfering RNA-mediated Suppression of Pyruvate Carboxylase (75 citations)
- Structure and functional analysis of the IGF‐II/IGF2R interaction (71 citations)
- New antibiotic caerin 1 peptides from the skin secretion of the Australian tree frog Litoria chloris. Comparison of the activities of the caerin 1 peptides from the genus Litoria (54 citations)
In his most recent research, the most cited papers focused on:
John C. Wallace mainly focuses on Biochemistry, Biotin, DNA ligase, Pyruvate carboxylase and Ligand.
Biochemistry is often connected to Stereochemistry in his work.
His Biotin study combines topics in areas such as Biotin carboxyl carrier protein and Biotinylation.
His work on Biotin carboxylase is typically connected to Rhizobium etli as part of general Pyruvate carboxylase study, connecting several disciplines of science.
His work deals with themes such as Ligand binding assay, Cooperative binding, Ectodomain, Wild type and Click chemistry, which intersect with Ligand.
His work in Insulin-like growth factor covers topics such as Alanine scanning which are related to areas like Insulin.
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