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Yoshiaki Furukawa

Yoshiaki Furukawa

D-Index & Metrics

Neuroscience

D-Index
56
Citations
11237
World Ranking
4524
National Ranking
137

Overview

Yoshiaki Furukawa is affiliated with Juntendo University in Japan, with a research focus spanning medicine and biochemistry, genetics, and molecular biology. Their scholarly work predominantly centers on neurology, molecular biology, physiology, cellular and molecular neuroscience, and genetics.

The scientist's research primarily covers topics such as amyotrophic lateral sclerosis (ALS) research, neurogenetic and muscular disorders, Alzheimer's disease research and treatments, trace elements in health, Parkinson's disease mechanisms and treatments, prion diseases and protein misfolding, as well as cerebrospinal fluid and hydrocephalus.

Frequent publication venues for their work include the Journal of Biological Chemistry, eLife, Proceedings for Annual Meeting of The Japanese Pharmacological Society, Translational Neurodegeneration, and Neuroscience Research.

Collaborative efforts feature regular co-authors including Eiichi Tokuda, Atsuko Shintani, Kaori Sue, Mikako Hirose, and Mito Asano, reflecting a consistent multidisciplinary approach.

Among recent papers authored or co-authored by Yoshiaki Furukawa are:

  • Does wild-type Cu/Zn-superoxide dismutase have pathogenic roles in amyotrophic lateral sclerosis?, 2020, Translational Neurodegeneration
  • The identified clinical features of Parkinson's disease in homo-, heterozygous and digenic variants of PINK1, 2020, Neurobiology of Aging
  • Stagnation of glymphatic interstitial fluid flow and delay in waste clearance in the SOD1-G93A mouse model of ALS, 2020, Neuroscience Research
  • Metal distribution in Cu/Zn-superoxide dismutase revealed by native mass spectrometry, 2022, Free Radical Biology and Medicine
  • FUS regulates RAN translation through modulating the G-quadruplex structure of GGGGCC repeat RNA in C9orf72-linked ALS/FTD, 2023, eLife

Best Publications

  • Conversion to the amyotrophic lateral sclerosis phenotype is associated with intermolecular linked insoluble aggregates of SOD1 in mitochondria

    Han Xiang Deng;Yong Shi;Yoshiaki Furukawa;Hong Zhai

  • Preferential loss of serotonin markers in caudate versus putamen in Parkinson's disease

    Stephen J. Kish;Junchao Tong;Oleh Hornykiewicz;Ali Rajput

  • Complete loss of post-translational modifications triggers fibrillar aggregation of SOD1 in the familial form of amyotrophic lateral sclerosis.

    Yoshiaki Furukawa;Kumi Kaneko;Koji Yamanaka;Thomas V. O'Halloran

  • Marked disparity between age-related changes in dopamine and other presynaptic dopaminergic markers in human striatum

    John W. Haycock;Laurence Becker;Lee Ang;Yoshiaki Furukawa

  • Current concepts in the diagnosis and management of Parkinson's disease

    Mark Guttman;Stephen J. Kish;Yoshiaki Furukawa

  • Brain α-synuclein accumulation in multiple system atrophy, Parkinson's disease and progressive supranuclear palsy: a comparative investigation

    Junchao Tong;Henry Wong;Mark Guttman;Lee C. Ang

  • Distribution of Monoamine Oxidase Proteins in Human Brain: Implications for Brain Imaging Studies

    Junchao Tong;Jeffrey H Meyer;Yoshiaki Furukawa;Isabelle Boileau

  • Decreased cerebral cortical serotonin transporter binding in ecstasy users: a positron emission tomography/[11C]DASB and structural brain imaging study

    Stephen J. Kish;Jason Lerch;Yoshiaki Furukawa;Junchao Tong

  • Regional distribution of serotonin transporter protein in postmortem human brain: is the cerebellum a SERT-free brain region?

    Stephen J. Kish;Yoshiaki Furukawa;Li-Jan Chang;Junchao Tong

  • Dystonia with motor delay in compound heterozygotes for GTP-cyclohydrolase I gene mutations

    Furukawa Y;Kish Sj;Bebin Em;Jacobson Rd

  • Brain monoamine oxidase B and A in human parkinsonian dopamine deficiency disorders.

    Junchao Tong;Gausiha Rathitharan;Jeffrey H Meyer;Yoshiaki Furukawa

  • Higher Binding of the Dopamine D3 Receptor-Preferring Ligand [11C]-(+)-Propyl-Hexahydro-Naphtho-Oxazin in Methamphetamine Polydrug Users: A Positron Emission Tomography Study

    Isabelle Boileau;Doris Payer;Sylvain Houle;Arian Behzadi

  • Striatal biopterin and tyrosine hydroxylase protein reduction in dopa-responsive dystonia.

    Y. Furukawa;T.G. Nygaard;M. Gütlich;A.H. Rajput

  • Gender-related penetrance and de novo GTP-cyclohydrolase I gene mutations in dopa-responsive dystonia.

    Y. Furukawa;A. E. Lang;J. M. Trugman;T. D. Bird

  • Striatal serotonin is depleted in brain of a human MDMA (Ecstasy) user

    S.J. Kish;Y. Furukawa;L. Ang;S.P. Vorce

  • RNA-binding Protein TLS Is a Major Nuclear Aggregate-interacting Protein in Huntingtin Exon 1 with Expanded Polyglutamine-expressing Cells

    Hiroshi Doi;Kazumasa Okamura;Peter O. Bauer;Yoshiaki Furukawa

  • Dopa-responsive dystonia simulating spastic paraplegia due to tyrosine hydroxylase (TH) gene mutations.

    Y. Furukawa;W.D. Graf;H. Wong;M. Shimadzu

  • Striatal dopaminergic and serotonergic markers in human heroin users.

    Stephen J Kish;Kathryn S Kalasinsky;Peter Derkach;Gregory A Schmunk

  • Regulatory Role of RNA Chaperone TDP-43 for RNA Misfolding and Repeat-Associated Translation in SCA31

    Taro Ishiguro;Nozomu Sato;Morio Ueyama;Nobuhiro Fujikake

  • GTP-cyclohydrolase I gene mutations in hereditary progressive and dopa-responsive dystonia

    Y Furukawa;M Shimadzu;A H Rajput;Y Shimizu

  • Brain proteasomal function in sporadic Parkinson's disease and related disorders

    Yoshiaki Furukawa;Sophie Vigouroux;Henry Wong;Mark Guttman

  • Decreased brain protein levels of cytochrome oxidase subunits in Alzheimer's disease and in hereditary spinocerebellar ataxia disorders: a nonspecific change?

    Stephen J. Kish;Frank Mastrogiacomo;Mark Guttman;Yoshiaki Furukawa

  • Decreased binding of the D3 dopamine receptor-preferring ligand [11C]-(+)-PHNO in drug-naive Parkinson's disease

    Isabelle Boileau;Isabelle Boileau;Mark Guttman;Pablo Rusjan;John R. Adams

  • Striatal dopamine in early-onset primary torsion dystonia with the DYT1 mutation.

    Yoshiaki Furukawa;Oleh Hornykiewicz;Stanley Fahn;Stephen J. Kish

Frequent Co-Authors

Isabelle Boileau
Isabelle Boileau Centre for Addiction and Mental Health
John W. Haycock
John W. Haycock Louisiana State University Health Sciences Center New Orleans
Martin Zack
Martin Zack University of Toronto
Massimo Pandolfo
Massimo Pandolfo McGill University
Guy A. Rouleau
Guy A. Rouleau Montreal Neurological Institute and Hospital
Paul J. Fletcher
Paul J. Fletcher Centre for Addiction and Mental Health
Tony P. George
Tony P. George Centre for Addiction and Mental Health
Christian Pifl
Christian Pifl Medical University of Vienna
Hideki Mochizuki
Hideki Mochizuki Osaka University
Thomas D. Bird
Thomas D. Bird University of Washington

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