World's Best Scientists 2026 revealed!

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Neuroscience

D-Index
42
Citations
6709
World Ranking
7670
National Ranking
49

Overview

Christian Pifl is affiliated with the Medical University of Vienna in Austria. Their research spans multiple disciplines, with a primary focus in the field of Materials Science and its intersections with neuroscience and molecular biology.

The scientist's publication record highlights significant contributions in several main fields of study, including:

  • Materials Chemistry
  • Cellular and Molecular Neuroscience
  • Molecular Biology
  • Neurology
  • Physiology

Their research topics reflect an interdisciplinary approach involving both chemical and biological sciences, emphasizing:

  • Crystallization and Solubility Studies
  • X-ray Diffraction in Crystallography
  • Neuroscience and Neuropharmacology Research
  • Neurotransmitter Receptor Influence on Behavior
  • Receptor Mechanisms and Signaling
  • Parkinson's Disease Mechanisms and Treatments
  • Ion channel regulation and function

Christian Pifl has published extensively in a variety of scientific journals. Frequent publication venues include:

  • The Cambridge Structural Database
  • bioRxiv (Cold Spring Harbor Laboratory)
  • npj Parkinson's Disease
  • eLife
  • Psychopharmacology

Among recent papers, noteworthy titles include:

  • "Oleh Hornykiewicz, a giant in the understanding and treatment of Parkinson disease" (2021), published in npj Parkinson's Disease
  • "Handling of intracellular K+ determines voltage dependence of plasmalemmal monoamine transporter function" (2021), published in eLife
  • "Behavioral and dopamine transporter binding properties of the modafinil analog (S, S)-CE-158: reversal of the motivational effects of tetrabenazine and enhancement of progressive ratio responding" (2020), published in Psychopharmacology
  • "Reinstatement of synaptic plasticity in the aging brain through specific dopamine transporter inhibition" (2021), published in Molecular Psychiatry
  • "A mechanism of uncompetitive inhibition of the serotonin transporter" (2023), published in eLife

Collaborations have played a significant role in their research, with frequent coauthors including:

  • Harald H. Sitte
  • Predrag Kalaba
  • Vladimir Dragačević
  • Gert Lübec
  • Martin Zehl

Best Publications

  • Delineation of discrete domains for substrate, cocaine, and tricyclic antidepressant interactions using chimeric dopamine-norepinephrine transporters.

    B. Giros;Yan-Min Wang;S. Suter;S. B. Mcleskey

  • Induction of functional dopamine neurons from human astrocytes in vitro and mouse astrocytes in a Parkinson's disease model

    Pia Rivetti di Val Cervo;Roman A Romanov;Roman A Romanov;Giada Spigolon;Débora Masini

  • The Parkinson's disease-associated DJ-1 protein is a transcriptional co-activator that protects against neuronal apoptosis

    Jin Xu;Nan Zhong;Haoyong Wang;Joshua E. Elias

  • Effect of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine on the regional distribution of brain monoamines in the rhesus monkey.

    Ch. Pifl;G. Schingnitz;O. Hornykiewicz

  • Central control of fever and female body temperature by RANKL/RANK

    Reiko Hanada;Andreas Leibbrandt;Toshikatsu Hanada;Shiho Kitaoka

  • The dopamine autoreceptor agonist B-HT 920 stimulates denervated postsynaptic brain dopamine receptors in rodent and primate models of Parkinson's disease: a novel approach to treatment.

    Dieter Hinzen;Oleh Hornykiewicz;Walter Kobinger;Ludwig Pichler

  • Dopamine transporter expression confers cytotoxicity to low doses of the parkinsonism-inducing neurotoxin 1-methyl-4-phenylpyridinium.

    Christian Pifl;Brunos Giros;Marc G. Caron

  • Differential changes in neurochemical markers of striatal dopamine nerve terminals in idiopathic Parkinson's disease

    J. M. Wilson;A. I. Levey;A. Rajput;L. Ang

  • Mechanism of the dopamine-releasing actions of amphetamine and cocaine: plasmalemmal dopamine transporter versus vesicular monoamine transporter.

    C Pifl;H Drobny;H Reither;O Hornykiewicz

  • Carrier-Mediated Release, Transport Rates, and Charge Transfer Induced by Amphetamine, Tyramine, and Dopamine in Mammalian Cells Transfected with the Human Dopamine Transporter

    H. H. Sitte;S. Huck;H. Reither;S. Boehm

  • Hepatic encephalopathy in thioacetamide‐induced acute liver failure in rats: Characterization of an improved model and study of amino acid‐ergic neurotransmission

    Christof Zimmermann;Peter Ferenci;Christian Pifl;Cihan Yurdaydin

  • Globus pallidus dopamine and Parkinson motor subtypes Clinical and brain biochemical correlation

    A. H. Rajput;H. H. Sitte;A. Rajput;M. E. Fenton

  • Is Parkinson's disease a vesicular dopamine storage disorder?: Evidence from a study in isolated synaptic vesicles of human and nonhuman primate striatum

    Christian Pifl;Alex Rajput;Harald Reither;Javier Blesa

  • Regional heterogeneity in the distribution of neurotransmitter markers in the rat hippocampus.

    H. Hörtnagl;M.L. Berger;G. Sperk;Ch. Pifl

  • Striatal biopterin and tyrosine hydroxylase protein reduction in dopa-responsive dystonia.

    Y. Furukawa;T.G. Nygaard;M. Gütlich;A.H. Rajput

  • Transporter-mediated release: a superfusion study on human embryonic kidney cells stably expressing the human serotonin transporter.

    Petra Scholze;Julia Zwach;Alexandra Kattinger;Christian Pifl

  • The nigrostriatal system in the presymptomatic and symptomatic stages in the MPTP monkey model: a PET, histological and biochemical study.

    J. Blesa;C. Pifl;M.A. Sánchez-González;C. Juri;C. Juri

  • Catecholamine transporters and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity: studies comparing the cloned human noradrenaline and human dopamine transporter.

    C Pifl;O Hornykiewicz;B Giros;M G Caron

  • Thalamic noradrenaline in Parkinson's disease: deficits suggest role in motor and non-motor symptoms

    Christian Pifl;Stephen J. Kish;Oleh Hornykiewicz

  • Disturbed neurotransmitter homeostasis in ether lipid deficiency.

    Fabian Dorninger;Theresa König;Petra Scholze;Michael L Berger

  • Quantitative analysis of inward and outward transport rates in cells stably expressing the cloned human serotonin transporter: inconsistencies with the hypothesis of facilitated exchange diffusion.

    Harald H. Sitte;Birgit Hiptmair;Julia Zwach;Christian Pifl

  • Increased serotoninergic and noradrenergic activity in hepatic encephalopathy in rats with thioacetamide-induced acute liver failure.

    Cihan Yurdaydin;Heide Hörtnagl;Petra Steindl;Christof Zimmermann

Frequent Co-Authors

Tibor Harkany
Tibor Harkany Medical University of Vienna
Günther Sperk
Günther Sperk Innsbruck Medical University
Bruno Giros
Bruno Giros McGill University
Nicolas Singewald
Nicolas Singewald University of Innsbruck
Tomas Hökfelt
Tomas Hökfelt Karolinska Institute
Marco Pistis
Marco Pistis University of Cagliari
Hironobu Yoshimatsu
Hironobu Yoshimatsu Oita University
Mercè Correa
Mercè Correa Jaume I University
Luigi Zecca
Luigi Zecca National Academies of Sciences, Engineering, and Medicine
Jan Mulder
Jan Mulder Karolinska Institute

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