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Genetics

D-Index
60
Citations
28637
World Ranking
3104
National Ranking
1358

Overview

Amanda J. Myers is affiliated with the University of Miami in the United States. Their research spans multiple scientific fields with a focus on medicine, biochemistry, genetics, molecular biology, and neuroscience. Within these disciplines, Myers has a notable publication record related to physiology, genetics, molecular biology, neurology, and surgery.

Their work centers primarily on Alzheimer's disease research and treatments, genetic associations and epidemiology, bioinformatics and genomic networks, diet and metabolism studies, nuclear receptors and signaling, neuroinflammation and neurodegeneration mechanisms, as well as dementia and cognitive impairment research.

Recent papers authored or co-authored by Myers include:

  • "Exceptionally low likelihood of Alzheimer's dementia in APOE2 homozygotes from a 5,000-person neuropathological study" (2020), published in Nature Communications
  • "What does heritability of Alzheimer's disease represent?" (2023), published in PLoS ONE
  • "Transcriptome-wide association study of post-trauma symptom trajectories identified GRIN3B as a potential biomarker for PTSD development" (2021), published in Neuropsychopharmacology
  • "Integration of peripheral transcriptomics, genomics, and interactomics following trauma identifies causal genes for symptoms of post-traumatic stress and major depression" (2021), published in Molecular Psychiatry
  • "ESHRD: deconvolution of brain homogenate RNA expression data to identify cell-type-specific alterations in Alzheimer's disease" (2020), published in Aging

Frequently published venues include PLoS ONE and The Journal of Urology with two papers each, along with Nature Communications, Neuropsychopharmacology, and Molecular Psychiatry.

Myers often collaborates with a group of researchers in their field. Frequent co-authors are:

  • John Hardy
  • Matthew J. Huentelman
  • Ganna Leonenko
  • Valentina Escott-Price
  • Emily Baker

The breadth of Myers's research includes investigations into the genetic basis of diseases, mechanisms underlying neurodegeneration, and applications of transcriptomics to trauma-related disorders. Their publication history and collaborative network reflect an interdisciplinary approach to understanding complex neurological diseases and their genetic components.

Best Publications

  • Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

    Jean-Charles Lambert;Jean-Charles Lambert;Jean-Charles Lambert;Carla A Ibrahim-Verbaas;Denise Harold;Adam C Naj

  • Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.

    Adam C. Naj;Gyungah Jun;Gary W. Beecham;Li-San Wang

  • Integrated Systems Approach Identifies Genetic Nodes and Networks in Late-Onset Alzheimer’s Disease

    Bin Zhang;Chris Gaiteri;Liviu Gabriel Bodea;Zhi Wang

  • Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease.

    Valentina Escott-Price;Céline Bellenguez;Li-San Wang;Seung-Hoan Choi

  • Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

    Rebecca Sims;Sven J. Van Der Lee;Adam C. Naj;Céline Bellenguez;Céline Bellenguez

  • Post-traumatic stress disorder is associated with PACAP and the PAC1 receptor

    Kerry J. Ressler;Kerry J. Ressler;Kerry J. Ressler;Kristina B. Mercer;Bekh Bradley;Bekh Bradley;Tanja Jovanovic

  • A high-density whole-genome association study reveals that APOE is the major susceptibility gene for sporadic late-onset Alzheimer's disease

    Keith D. Coon;Amanda J. Myers;David W. Craig;Jennifer A. Webster

  • GAB2 Alleles Modify Alzheimer's Risk in APOE ε4 Carriers

    Eric M. Reiman;Jennifer A. Webster;Amanda J. Myers;Amanda J. Myers;John Hardy;John Hardy

  • A survey of genetic human cortical gene expression.

    Amanda J Myers;Amanda J Myers;J Raphael Gibbs;Jennifer A Webster;Kristen Rohrer

  • Susceptibility Locus for Alzheimer's Disease on Chromosome 10

    Amanda Myers;Peter Holmans;Helen Marshall;Jennifer Kwon

  • The structure of the presenilin 1 (S182) gene and identification of six novel mutations in early onset AD families

    Robert Clark;Michael Hutton;Rebecca Fuldner;Sue Froelich

  • Exceptionally low likelihood of Alzheimer’s dementia in APOE2 homozygotes from a 5,000-person neuropathological study

    Eric M Reiman;Joseph F Arboleda-Velasquez;Yakeel T Quiroz;Matthew J Huentelman

  • Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias.

    Gary W. Beecham;Kara Hamilton;Adam C. Naj;Eden R. Martin

  • Genetic Control of Human Brain Transcript Expression in Alzheimer Disease

    Jennifer A. Webster;Jennifer A. Webster;J. Raphael Gibbs;J. Raphael Gibbs;Jennifer Clarke;Monika Ray

  • A novel Alzheimer disease locus located near the gene encoding tau protein

    G. Jun;C. A. Ibrahim-Verbaas;M. Vronskaya;J-C Lambert;J-C Lambert;J-C Lambert

  • Linkage disequilibrium fine mapping and haplotype association analysis of the tau gene in progressive supranuclear palsy and corticobasal degeneration

    A. M. Pittman;A. J. Myers;P. Abou-Sleiman;H. C. Fung

  • Common genetic variation within the Low-Density Lipoprotein Receptor-Related Protein 6 and late-onset Alzheimer's disease

    Giancarlo V. De Ferrari;Andreas Papassotiropoulos;Andreas Papassotiropoulos;Travis Biechele;Fabienne Wavrant De-Vrieze

  • Association of CR1, CLU, and PICALM with Alzheimer’s disease in a cohort of clinically characterized and neuropathologically verified individuals

    Jason J. Corneveaux;Amanda J. Myers;April N. Allen;Jeremy J. Pruzin

  • The H1c haplotype at the MAPT locus is associated with Alzheimer's disease

    A.J. Myers;M. Kaleem;L. Marlowe;A.M. Pittman

  • The MAPT H1c risk haplotype is associated with increased expression of tau and especially of 4 repeat containing transcripts

    Amanda J. Myers;Alan M. Pittman;Alice S. Zhao;Kristen Rohrer

Frequent Co-Authors

John Hardy
John Hardy University College London
Philip L. De Jager
Philip L. De Jager Columbia University
Alison Goate
Alison Goate Icahn School of Medicine at Mount Sinai
Eric M. Reiman
Eric M. Reiman Arizona State University
Matthew J. Huentelman
Matthew J. Huentelman Translational Genomics Research Institute
Simon Lovestone
Simon Lovestone University of Oxford
Julie Williams
Julie Williams Cardiff University
Peter Holmans
Peter Holmans Cardiff University
David A. Bennett
David A. Bennett Rush University Medical Center
Lesley Jones
Lesley Jones Cardiff University

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