Iain A. Drummond

Overview

Best Publications

• The centrosomal protein nephrocystin-6 is mutated in Joubert syndrome and activates transcription factor ATF4

  John A. Sayer;John A. Sayer;Edgar A. Otto;John F. O'Toole;Gudrun Nurnberg

  764
  Citations

• Cilia-driven fluid flow in the zebrafish pronephros, brain and Kupffer's vesicle is required for normal organogenesis

  Albrecht G. Kramer-Zucker;Felix Olale;Courtney J. Haycraft;Bradley K. Yoder

  721
  Citations

• Mutations in INVS encoding inversin cause nephronophthisis type 2, linking renal cystic disease to the function of primary cilia and left-right axis determination.

  Edgar A. Otto;Bernhard Schermer;Tomoko Obara;John F. O'Toole

  720
  Citations

• Repression of the insulin-like growth factor II gene by the Wilms tumor suppressor WT1.

  IA Drummond;SL Madden;P Rohwer-Nutter;GI Bell

  650
  Citations

• Positional cloning uncovers mutations in PLCE1 responsible for a nephrotic syndrome variant that may be reversible.

  Bernward Hinkes;Roger C. Wiggins;Rasheed Gbadegesin;Christopher N. Vlangos

  647
  Citations

• Early development of the zebrafish pronephros and analysis of mutations affecting pronephric function

  Iain A. Drummond;Arindam Majumdar;Hartmut Hentschel;Marlies Elger

  534
  Citations

• Exome Capture Reveals ZNF423 and CEP164 Mutations, Linking Renal Ciliopathies to DNA Damage Response Signaling

  Moumita Chaki;Rannar Airik;Amiya K. Ghosh;Rachel H. Giles

  431
  Citations

• Increased expression of the insulin-like growth factor I receptor gene, IGF1R, in Wilms tumor is correlated with modulation of IGF1R promoter activity by the WT1 Wilms tumor gene product.

  H Werner;G G Re;I A Drummond;V P Sukhatme

  376
  Citations

• Polycystin 1 is required for the structural integrity of blood vessels.

  Keetae Kim;Iain Drummond;Oxana Ibraghimov-Beskrovnaya;Katherine Klinger

  375
  Citations

• The Polycystic Kidney Disease 1 Gene Product Modulates Wnt Signaling

  Emily Kim;Thierry Arnould;Lorenz K. Sellin;Thomas Benzing

  315
  Citations

• CCDC103 mutations cause primary ciliary dyskinesia by disrupting assembly of ciliary dynein arms

  Jennifer R Panizzi;Anita Becker-Heck;Victoria H Castleman;Dalal A Al-Mutairi;Dalal A Al-Mutairi

  280
  Citations

• roundabout4 is essential for angiogenesis in vivo.

  Victoria M. Bedell;Sang-Yeob Yeo;Kye Won Park;Jeffrey Chung

  257
  Citations

• Organization of the pronephric filtration apparatus in zebrafish requires Nephrin, Podocin and the FERM domain protein Mosaic eyes.

  Albrecht G. Kramer-Zucker;Stephanie Wiessner;Abbie M. Jensen;Iain A. Drummond

  243
  Citations

• Notch signaling controls the differentiation of transporting epithelia and multiciliated cells in the zebrafish pronephros.

  Yan Liu;Narendra Pathak;Albrecht Kramer-Zucker;Iain A. Drummond

  240
  Citations

• Acute renal failure in zebrafish: a novel system to study a complex disease

  Dirk M. Hentschel;Kwon Moo Park;Lucia Cilenti;Antonis S. Zervos

  235
  Citations

• A defect in a novel Nek-family kinase causes cystic kidney disease in the mouse and in zebrafish.

  Shanming Liu;Weining Lu;Tomoko Obara;Shiei Kuida

  234
  Citations

• Zebrafish Ciliopathy Screen Plus Human Mutational Analysis Identifies C21orf59 and CCDC65 Defects as Causing Primary Ciliary Dyskinesia

  Christina Austin-Tse;Jan Halbritter;Maimoona B Zariwala;Renée M. Gilberti

  225
  Citations

• The zebrafish fleer gene encodes an essential regulator of cilia tubulin polyglutamylation.

  Narendra Pathak;Tomoko Obara;Steve Mangos;Yan Liu

  225
  Citations

• Transcriptional repression of the insulin-like growth factor I receptor (IGF-I-R) gene by the tumor suppressor WT1 involves binding to sequences both upstream and downstream of the IGF-I-R gene transcription start site.

  H Werner;F J Rauscher;V P Sukhatme;I A Drummond

  220
  Citations

• ZMYND10 Is Mutated in Primary Ciliary Dyskinesia and Interacts with LRRC6

  Maimoona A. Zariwala;Heon Yung Gee;Małgorzata Kurkowiak;Małgorzata Kurkowiak;Małgorzata Kurkowiak;Dalal A. Al-Mutairi;Dalal A. Al-Mutairi

  216
  Citations