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Steven S. Rosenfeld

Steven S. Rosenfeld

D-Index & Metrics

Biology and Biochemistry

D-Index
54
Citations
9867
World Ranking
15692
National Ranking
6538

Overview

Steven S. Rosenfeld is a researcher affiliated with the Mayo Clinic in the United States. Their work spans multiple areas within biochemistry, genetics, molecular biology, and medicine, with a primary focus on cellular and molecular mechanisms related to glioma diagnosis and treatment, microtubule and mitosis dynamics, and cellular mechanics.

Their research topics include:

  • Glioma Diagnosis and Treatment
  • Microtubule and mitosis dynamics
  • Cellular Mechanics and Interactions
  • RNA Research and Splicing
  • Histone Deacetylase Inhibitors Research
  • Advanced Electron Microscopy Techniques and Applications
  • Neuroscience and Neuropharmacology Research

Steven S. Rosenfeld has contributed extensively within the fields of study encompassing:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Within these broader fields, their work is further refined into subfields such as:

  • Cell Biology
  • Molecular Biology
  • Genetics
  • Cancer Research
  • Pulmonary and Respiratory Medicine

Among the most frequent publication venues for Rosenfeld are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Neuro-Oncology
  • Cell Reports
  • eLife
  • iScience

They have a consistent collaboration record with several coauthors, including:

  • Rajappa S. Kenchappa
  • Athanassios Dovas
  • Natanael Zarco
  • Alfredo Quiñones-Hinojosa
  • Peter A. Sims

Representative recent papers authored or co-authored by Steven S. Rosenfeld include:

  • The kinesin-5 tail domain directly modulates the mechanochemical cycle of the motor domain for anti-parallel microtubule sliding (2020, eLife)
  • Enhancing Brain Retention of a KIF11 Inhibitor Significantly Improves its Efficacy in a Mouse Model of Glioblastoma (2020, Scientific Reports)
  • Activation of STAT3 through combined SRC and EGFR signaling drives resistance to a mitotic kinesin inhibitor in glioblastoma (2022, Cell Reports)
  • The mechanism of kinesin inhibition by kinesin-binding protein (2020, eLife)
  • Myosin 10 Regulates Invasion, Mitosis, and Metabolic Signaling in Glioblastoma (2020, iScience)

Best Publications

  • Multicenter Phase II Trial of Temozolomide in Patients With Anaplastic Astrocytoma or Anaplastic Oligoastrocytoma at First Relapse

    W. K.Alfred Yung;Michael D. Prados;Ricardo Yaya-Tur;Steven S. Rosenfeld

  • The kinetic mechanism of myosin V.

    Enrique M. De La Cruz;Amber L. Wells;Steven S. Rosenfeld;E. Michael Ostap

  • A Phase I Open-Label, Dose-Escalation, Multi-Institutional Trial of Injection with an E1B-Attenuated Adenovirus, ONYX-015, into the Peritumoral Region of Recurrent Malignant Gliomas, in the Adjuvant Setting

    E. Antonio Chiocca;Khalid M. Abbed;Stephen Tatter;David N. Louis

  • The role of myosin II in glioma invasion of the brain.

    Christopher Beadle;Marcella C. Assanah;Pascale Monzo;Richard Vallee

  • Phase I and correlative biology study of cilengitide in patients with recurrent malignant glioma

    L. Burt Nabors;Tom Mikkelsen;Steven S. Rosenfeld;Fred Hochberg

  • FDG-PET in differentiating lymphoma from nonmalignant central nervous system lesions in patients with AIDS.

    J. M. Hoffman;H. A. Waskin;T. Schifter;M. W. Hanson

  • Proteolytic fragments of troponin C. Localization of high and low affinity Ca2+ binding sites and interactions with troponin I and troponin T.

    P C Leavis;S S Rosenfeld;J Gergely;Z Grabarek

  • Shifting the optimal stiffness for cell migration.

    Benjamin L. Bangasser;Ghaidan A. Shamsan;Clarence E. Chan;Kwaku N. Opoku

  • Phase I Single-Dose Study of Intracavitary-Administered Iodine-131-TM-601 in Adults With Recurrent High-Grade Glioma

    Adam N. Mamelak;Steven Rosenfeld;Richard Bucholz;Andrew Raubitschek

  • Kinetic Tuning of Myosin via a Flexible Loop Adjacent to the Nucleotide Binding Pocket

    H. Lee Sweeney;Steven S. Rosenfeld;Fred Brown;Lynn Faust

  • Stepping and stretching. How kinesin uses internal strain to walk processively.

    Steven S. Rosenfeld;Polly M. Fordyce;Geraldine M. Jefferson;Peter H. King;Peter H. King

  • Determinants of Maximal Force Transmission in a Motor-Clutch Model of Cell Traction in a Compliant Microenvironment

    Benjamin L. Bangasser;Steven S. Rosenfeld;David J. Odde

  • A universal pathway for kinesin stepping

    Bason E Clancy;William M Behnke-Parks;Johan O L Andreasson;Steven S Rosenfeld

  • A model of myosin V processivity.

    Steven S. Rosenfeld;H. Lee Sweeney

  • Nitric oxide-dependent generation of reactive species in sickle cell disease: Actin tyrosine nitration induces defective cytoskeletal polymerization

    Mutay Aslan;Thomas M. Ryan;Tim M. Townes;Lori Coward

  • Proteolytic fragments of troponin C. Interactions with the other troponin subunits and biological activity.

    Z Grabarek;W Drabikowski;P C Leavis;S S Rosenfeld

  • The mitotic kinesin KIF11 is a driver of invasion, proliferation, and self-renewal in glioblastoma.

    Monica Venere;Craig Horbinski;James F. Crish;Xun Jin

  • Glioblastoma models reveal the connection between adult glial progenitors and the proneural phenotype

    Liang Lei;Adam M. Sonabend;Paolo Guarnieri;Craig Soderquist

  • Myosin IIb is unconventionally conventional.

    Steven S. Rosenfeld;Jun Xing;Li Qiong Chen;H. Lee Sweeney

  • Regression of Recurrent Malignant Gliomas With Convection-Enhanced Delivery of Topotecan

    Jeffrey N. Bruce;Robert L. Fine;Peter Canoll;Jonathan Yun

Frequent Co-Authors

Anne Houdusse
Anne Houdusse Université Paris Cité
Jeremy N. Rich
Jeremy N. Rich University of Pittsburgh
H. Lee Sweeney
H. Lee Sweeney University of Florida
Steven P. Gross
Steven P. Gross University of California, Irvine
Casper C. Hoogenraad
Casper C. Hoogenraad Utrecht University
Michel O. Steinmetz
Michel O. Steinmetz Paul Scherrer Institute
Jann N. Sarkaria
Jann N. Sarkaria Mayo Clinic
Patrick Y. Wen
Patrick Y. Wen Harvard University
David D. Thomas
David D. Thomas University of Minnesota
William O. Tatum
William O. Tatum Mayo Clinic

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