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Molecular Biology

D-Index
65
Citations
20101
World Ranking
1652
National Ranking
836

Overview

Stephen A. Duncan is affiliated with the Medical University of South Carolina in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with particular focus on Molecular Biology, Hepatology, Surgery, Genetics, and Epidemiology.

Their work addresses topics such as CRISPR and Genetic Engineering, Epigenetics and DNA Methylation, Pluripotent Stem Cells Research, Genomics and Chromatin Dynamics, Liver physiology and pathology, Genetics and Neurodevelopmental Disorders, and Mitochondrial Function and Pathology.

Frequent collaborators of Stephen A. Duncan include:

  • James A. Heslop
  • Behshad Pournasr
  • Jui-Tung Liu
  • Josef Blaszkiewicz
  • Paula Traktman

Publication venues where Stephen A. Duncan has contributed multiple works include:

  • Cell Reports
  • Scientific Reports
  • Genes
  • Communications Biology
  • Journal of The Electrochemical Society

Selected recent publications featuring Stephen A. Duncan's contributions are:

  • "GATA6 defines endoderm fate by controlling chromatin accessibility during differentiation of human-induced pluripotent stem cells," 2021, Cell Reports
  • "CDK5-PRMT1-WDR24 signaling cascade promotes mTORC1 signaling and tumor growth," 2023, Cell Reports
  • "Advancements in Disease Modeling and Drug Discovery Using iPSC-Derived Hepatocyte-like Cells," 2022, Genes
  • "Modelling the Impedance Response of Graded LiFePO4 Cathodes for Li-Ion Batteries," 2022, Journal of The Electrochemical Society
  • "FoxA factors: the chromatin key and doorstop essential for liver development and function," 2020, Genes & Development

Best Publications

  • Requirement of the transcription factor GATA4 for heart tube formation and ventral morphogenesis.

    Jeffery D. Molkentin;Qing Lin;Stephen A. Duncan;Eric N. Olson

  • Highly efficient generation of human hepatocyte-like cells from induced pluripotent stem cells.

    Karim Si‐Tayeb;Fallon K. Noto;Masato Nagaoka;Jixuan Li

  • Organogenesis and development of the liver.

    Karim Si-Tayeb;Frédéric P. Lemaigre;Stephen A. Duncan;Stephen A. Duncan

  • Mammalian hepatocyte differentiation requires the transcription factor HNF-4alpha.

    Jixuan Li;Gang Ning;Stephen A. Duncan

  • Hepatocyte nuclear factor 4alpha controls the development of a hepatic epithelium and liver morphogenesis.

    Fereshteh Parviz;Christine Matullo;Wendy D Garrison;Laura Savatski

  • Disruption of the HNF-4 gene, expressed in visceral endoderm, leads to cell death in embryonic ectoderm and impaired gastrulation of mouse embryos.

    William S. Chen;Kada Manova;Daniel C. Weinstein;Stephen A. Duncan

  • The orphan nuclear receptor HNF4alpha determines PXR- and CAR-mediated xenobiotic induction of CYP3A4.

    Rommel G Tirona;Wooin Lee;Brenda F Leake;Lu-Bin Lan

  • Expression of transcription factor HNF-4 in the extraembryonic endoderm, gut, and nephrogenic tissue of the developing mouse embryo: HNF-4 is a marker for primary endoderm in the implanting blastocyst

    Stephen A. Duncan;Katia Manova;William S. Chen;Pamela Hoodless

  • The maturity-onset diabetes of the young (MODY1) transcription factor HNF4alpha regulates expression of genes required for glucose transport and metabolism.

    Markus Stoffel;Stephen A. Duncan

  • Cardiac-Specific Deletion of Gata4 Reveals Its Requirement for Hypertrophy, Compensation, and Myocyte Viability

    Toru Oka;Marjorie Maillet;Alistair J. Watt;Robert J. Schwartz

  • Regulation of a Transcription Factor Network Required for Differentiation and Metabolism

    Stephen A. Duncan;M. Angeles Navas;Daniel Dufort;Janet Rossant

  • GATA4 is essential for formation of the proepicardium and regulates cardiogenesis

    Alistair J. Watt;Michele A. Battle;Jixuan Li;Stephen A. Duncan

  • Normal cerebellar development but susceptibility to seizures in mice lacking G protein-coupled, inwardly rectifying K+ channel GIRK2

    Signorini S;Liao Yj;Duncan Sa;Jan Ly

  • ER Stress Controls Iron Metabolism Through Induction of Hepcidin

    Chiara Vecchi;Giuliana Montosi;Kezhong Zhang;Igor Lamberti

  • Embryonic development of the liver.

    Roong Zhao;Stephen A. Duncan

  • Murine gastrulation requires HNF-4 regulated gene expression in the visceral endoderm: tetraploid rescue of Hnf-4(−/−) embryos

    Stephen A. Duncan;Andras Nagy;Wendy Chan

  • HNF4: A central regulator of hepatocyte differentiation and function

    Alistair J. Watt;Wendy D. Garrison;Stephen A. Duncan

  • GATA6 is essential for embryonic development of the liver but dispensable for early heart formation.

    Roong Zhao;Alistair J. Watt;Jixuan Li;Jennifer Luebke-Wheeler

  • Hepatocyte nuclear factor 4α orchestrates expression of cell adhesion proteins during the epithelial transformation of the developing liver

    Michele A. Battle;Genevieve Konopka;Fereshteh Parviz;Alexandra Lerch Gaggl

  • Identification of small molecules for human hepatocyte expansion and iPS differentiation

    Jing Shan;Robert E Schwartz;Robert E Schwartz;Nathan T Ross;David J Logan

Frequent Co-Authors

Robert E. Schwartz
Robert E. Schwartz Cornell University
Wolfram Goessling
Wolfram Goessling Brigham and Women's Hospital
Edward E. Morrisey
Edward E. Morrisey University of Pennsylvania
Jeffery D. Molkentin
Jeffery D. Molkentin Cincinnati Children's Hospital Medical Center
Daniel J. Rader
Daniel J. Rader University of Pennsylvania
Markus Stoffel
Markus Stoffel University of Geneva
Randal J. Kaufman
Randal J. Kaufman Sanford Burnham Prebys Medical Discovery Institute
Paula Traktman
Paula Traktman Medical University of South Carolina
Klaus H. Kaestner
Klaus H. Kaestner University of Pennsylvania

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