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Medicine

D-Index
106
Citations
36110
World Ranking
6603
National Ranking
638

Overview

Simon S. Cross is affiliated with the University of Sheffield in the United Kingdom. Their research spans multiple areas within biochemistry, genetics, molecular biology, and medicine, emphasizing genetics and epidemiology related to breast cancer and gastrointestinal diseases.

Their recent publications include studies published mainly between 2020 and 2022, focusing on genetic susceptibility and risk factors for breast cancer, as well as research on coeliac disease diagnosis. Notable papers include:

  • Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses (2020, Nature Genetics)
  • Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes (2020, Nature Genetics)
  • Accuracy of a no-biopsy approach for the diagnosis of coeliac disease across different adult cohorts (2020, Gut)
  • Physical activity, sedentary time and breast cancer risk: a Mendelian randomisation study (2022, British Journal of Sports Medicine)
  • Combined Associations of a Polygenic Risk Score and Classical Risk Factors With Breast Cancer Risk (2020, JNCI Journal of the National Cancer Institute)

Frequent collaborators in their research include:

  • Angela Cox
  • Manjeet K. Bolla
  • Stig E. Bojesen
  • Kamila Czene
  • Hermann Brenner

Simon S. Cross has contributed to several publication venues, with multiple papers appearing in:

  • UNC Libraries
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Breast Cancer Research
  • Nutrients
  • Nature Genetics

Their main fields of study emphasize biochemistry, genetics, molecular biology, and medicine, supported by numerous publications particularly in:

  • Genetics
  • Molecular Biology
  • Gastroenterology
  • Oncology
  • Epidemiology

The core research topics addressed include:

  • BRCA gene mutations in cancer
  • Genetic Associations and Epidemiology
  • Celiac Disease Research and Management
  • Microscopic Colitis
  • Breast Cancer Treatment Studies
  • Bioinformatics and Genomic Networks
  • Eosinophilic Esophagitis

Best Publications

  • Subtyping of breast cancer by immunohistochemistry to investigate a relationship between subtype and short and long term survival: a collaborative analysis of data for 10,159 cases from 12 studies

    Fiona M. Blows;Kristy E. Driver;Marjanka K. Schmidt;Annegien Broeks

  • Association analysis identifies 65 new breast cancer risk loci

    Kyriaki Michailidou;Kyriaki Michailidou;Sara Lindström;Sara Lindström;Joe Dennis;Jonathan Beesley

  • Large-scale genotyping identifies 41 new loci associated with breast cancer risk

    Kyriaki Michailidou;Per Hall;Anna Gonzalez-Neira;Maya Ghoussaini

  • RAD51B in Familial Breast Cancer

    Liisa M. Pelttari;Sofia Khan;Mikko Vuorela;Johanna I. Kiiski

  • Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes

    Nasim Mavaddat;Kyriaki Michailidou;Kyriaki Michailidou;Joe Dennis;Michael Lush

  • Associations of Breast Cancer Risk Factors With Tumor Subtypes: A Pooled Analysis From the Breast Cancer Association Consortium Studies

    Xiaohong R. Yang;Jenny Chang-Claude;Ellen L. Goode;Fergus J. Couch

  • Introduction to neural networks.

    S.S. Cross;R.F. Harrison;R.L. Kennedy

  • Inherited Mutations in 17 Breast Cancer Susceptibility Genes Among a Large Triple-Negative Breast Cancer Cohort Unselected for Family History of Breast Cancer

    Fergus J. Couch;Steven N. Hart;Priyanka Sharma;Amanda Ewart Toland

  • Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer

    Kyriaki Michailidou;Jonathan Beesley;Sara Lindstrom;Sander Canisius

  • Prediction of Breast Cancer Risk Based on Profiling With Common Genetic Variants

    Nasim Mavaddat;Paul D.P. Pharoah;Kyriaki Michailidou;Jonathan Tyrer

  • MicroRNA related polymorphisms and breast cancer risk

    Sofia Khan;Dario Greco;Dario Greco;Kyriaki Michailidou;Roger L. Milne;Roger L. Milne

  • Heterogeneity of Breast Cancer Associations with Five Susceptibility Loci by Clinical and Pathological Characteristics

    Montserrat Garcia-Closas;Per Hall;Heli Nevanlinna;Karen Pooley

  • Genome-wide association studies identify four ER negative-specific breast cancer risk loci

    Montserrat Garcia-Closas;Fergus J. Couch;Sara Lindstrom;Kyriaki Michailidou

  • FRACTALS IN PATHOLOGY

    Simon S. Cross

  • A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor-negative breast cancer in the general population

    Antonis C. Antoniou;Xianshu Wang;Zachary S. Fredericksen;Lesley McGuffog

  • Matrix metalloproteinase levels are elevated in inflammatory bowel disease.

    Mark D. Baugh;Michael J. Perry;Anthony P. Hollander;D.Rhodri Davies

  • Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.

    Roger L Milne;Roger L Milne;Karoline B Kuchenbaecker;Karoline B Kuchenbaecker;Kyriaki Michailidou;Kyriaki Michailidou;Jonathan Beesley

  • Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses

    Haoyu Zhang;Haoyu Zhang;Thomas U. Ahearn;Julie Lecarpentier;Daniel Barnes

  • Indigo carmine-assisted high-magnification chromoscopic colonoscopy for the detection and characterisation of intraepithelial neoplasia in ulcerative colitis: a prospective evaluation.

    D. P. Hurlstone;D. S. Sanders;A. J. Lobo;M. E. McAlindon

  • A common variant at the TERT-CLPTM1L locus is associated with estrogen receptor-negative breast cancer

    Christopher A. Haiman;Gary K. Chen;Celine M. Vachon;Federico Canzian

Frequent Co-Authors

Graham G. Giles
Graham G. Giles University of Melbourne
Hiltrud Brauch
Hiltrud Brauch German Cancer Research Center
Roger L. Milne
Roger L. Milne Cancer Council Victoria
Jenny Chang-Claude
Jenny Chang-Claude German Cancer Research Center
Angela Cox
Angela Cox University of Sheffield
Irene L. Andrulis
Irene L. Andrulis University of Toronto
Melissa C. Southey
Melissa C. Southey Monash University
Stig E. Bojesen
Stig E. Bojesen University of Copenhagen
Fergus J. Couch
Fergus J. Couch Mayo Clinic
Barbara Burwinkel
Barbara Burwinkel Heidelberg University

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