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Neuroscience

D-Index
45
Citations
9906
World Ranking
6851
National Ranking
2961

Overview

Ziad S. Saad is a researcher affiliated with Janssen (Belgium) specializing primarily in medicine, with a focus on psychiatry and mental health, physiology, molecular biology, radiology, nuclear medicine and imaging, and neurology. Their work centers extensively on dementia and cognitive impairment research, especially Alzheimer's disease research and treatments.

Saad's published research includes work in venues such as Alzheimer's & Dementia, bioRxiv (Cold Spring Harbor Laboratory), JAMA Neurology, Neuropsychopharmacology, and Alzheimer's & Dementia Diagnosis Assessment & Disease Monitoring. Notable recent papers include:

  • "Head-to-head comparison of leading blood tests for Alzheimer's disease pathology" (2024) in Alzheimer's & Dementia
  • "Plasma p217+tau versus NAV4694 amyloid and MK6240 tau PET across the Alzheimer's continuum" (2022) in Alzheimer's & Dementia Diagnosis Assessment & Disease Monitoring
  • "Comparative analytical performance of multiple plasma Aβ42 and Aβ40 assays and their ability to predict positron emission tomography amyloid positivity" (2022) in Alzheimer's & Dementia
  • "Findings of Efficacy, Safety, and Biomarker Outcomes of Atabecestat in Preclinical Alzheimer Disease" (2021) in JAMA Neurology
  • "The effects of inhibition of fatty acid amide hydrolase (FAAH) by JNJ-42165279 in social anxiety disorder: a double-blind, randomized, placebo-controlled proof-of-concept study" (2020) in Neuropsychopharmacology

Frequent coauthors collaborating with Saad include Hartmuth C. Kolb, Gallen Triana-Baltzer, Victor L. Villemagne, Vincent Doré, and Christopher C. Rowe. These collaborators have contributed across numerous research papers, illustrating established scientific partnerships within the field.

The researcher's main topics of interest comprise:

  • Dementia and Cognitive Impairment Research
  • Alzheimer's Disease Research and Treatments
  • Medical Imaging Techniques and Applications
  • Functional Brain Connectivity Studies
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Amyloidosis: Diagnosis, Treatment, Outcomes
  • Statistical Methods in Clinical Trials

The body of Saad's work predominantly addresses molecular and imaging biomarkers relevant to Alzheimer's disease, cognition-related disorders, and neurodegenerative conditions. Emphasis is placed on the development and comparison of blood-based diagnostic tools, efficacy and safety of pharmacological agents targeting preclinical Alzheimer's disease, as well as clinical trial methodology in neuropsychiatric contexts.

Best Publications

  • Trouble at Rest: How Correlation Patterns and Group Differences Become Distorted After Global Signal Regression

    Ziad S. Saad;Stephen J. Gotts;Kevin Murphy;Gang Chen

  • Mapping sources of correlation in resting state FMRI, with artifact detection and removal

    Hang Joon Jo;Ziad S. Saad;W. Kyle Simmons;Lydia A. Milbury

  • Two distinct forms of functional lateralization in the human brain

    Stephen J. Gotts;Hang Joon Jo;Gregory L. Wallace;Ziad S. Saad

  • A New Method for Improving Functional-to-Structural MRI Alignment using Local Pearson Correlation

    Ziad S. Saad;Daniel R. Glen;Gang Chen;Michael S. Beauchamp

  • Integrated strategy for improving functional connectivity mapping using multiecho fMRI

    Prantik Kundu;Noah D. Brenowitz;Valerie Voon;Yulia Worbe

  • Linear mixed-effects modeling approach to FMRI group analysis

    Gang Chen;Ziad S. Saad;Jennifer C. Britton;Daniel S. Pine

  • Tracking ongoing cognition in individuals using brief, whole-brain functional connectivity patterns

    Javier Gonzalez-Castillo;Colin W. Hoy;Colin W. Hoy;Daniel A. Handwerker;Meghan E. Robinson

  • Whole-brain, time-locked activation with simple tasks revealed using massive averaging and model-free analysis

    Javier Gonzalez-Castillo;Ziad S. Saad;Daniel A. Handwerker;Souheil J. Inati

  • Effective Preprocessing Procedures Virtually Eliminate Distance-Dependent Motion Artifacts in Resting State FMRI.

    Hang Joon Jo;Stephen J. Gotts;Richard C. Reynolds;Peter A. Bandettini

  • Defining functional SMA and pre-SMA subregions in human MFC using resting state fMRI: functional connectivity-based parcellation method.

    Jae-Hun Kim;Jong-Min Lee;Hang Joon Jo;Sook Hui Kim

  • Spatial heterogeneity of the nonlinear dynamics in the FMRI BOLD response.

    Rasmus M. Birn;Ziad S. Saad;Peter A. Bandettini

  • The perils of global signal regression for group comparisons: a case study of Autism Spectrum Disorders

    Stephen J. Gotts;Ziad S. Saad;Hang Joon Jo;Gregory L. Wallace

  • SUMA: an interface for surface-based intra- and inter-subject analysis with AFNI

    Z.S. Saad;R.C. Reynolds;B. Argall;S. Japee

  • Applications of multivariate modeling to neuroimaging group analysis: a comprehensive alternative to univariate general linear model.

    Gang Chen;Nancy E. Adleman;Ziad S. Saad;Ellen Leibenluft

  • FATCAT: (an efficient) Functional and Tractographic Connectivity Analysis Toolbox.

    Paul A. Taylor;Ziad S. Saad

  • Simplified intersubject averaging on the cortical surface using SUMA.

    Brenna D. Argall;Ziad S. Saad;Michael S. Beauchamp

  • Correcting brain-wide correlation differences in resting-state FMRI.

    Ziad S. Saad;Richard C. Reynolds;Hang Joon Jo;Stephen J. Gotts

  • Analysis and use of FMRI response delays

    Ziad S. Saad;Kristina M. Ropella;Robert W. Cox;Edgar A. DeYoe

  • Three-Dimensional Digital Template Atlas of the Macaque Brain.

    Colin Reveley;Audrūnas Gruslys;Frank Q. Ye;Daniel Glen

  • FMRI group analysis combining effect estimates and their variances

    Gang Chen;Ziad S. Saad;Audrey R. Nath;Michael S. Beauchamp

  • SUMA

    Unknown

Frequent Co-Authors

Robert W. Cox
Robert W. Cox National Institutes of Health
Peter A. Bandettini
Peter A. Bandettini National Institutes of Health
Gang Chen
Gang Chen National Institutes of Health
Alex Martin
Alex Martin National Institutes of Health
Jean-Baptiste Poline
Jean-Baptiste Poline Montreal Neurological Institute and Hospital
Rasmus M. Birn
Rasmus M. Birn University of Wisconsin–Madison
Michael S. Beauchamp
Michael S. Beauchamp University of Pennsylvania
W. Kyle Simmons
W. Kyle Simmons Oklahoma State University Center for Health Sciences
Maura L. Furey
Maura L. Furey Janssen (Belgium)

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