D-Index & Metrics Best Publications

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Genetics and Molecular Biology D-index 63 Citations 16,427 137 World Ranking 2081 National Ranking 1049

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Cancer
  • DNA

R. S. K. Chaganti focuses on Molecular biology, Genetics, Cancer research, Chromosomal translocation and Cytogenetics. His studies deal with areas such as Raji cell, BCL6, Transcription factor, Fluorescence in situ hybridization and B-cell receptor as well as Molecular biology. The study of Genetics is intertwined with the study of B-cell lymphoma in a number of ways.

R. S. K. Chaganti interconnects Sunitinib, Kidney cancer, Renal cell carcinoma and Embryonal carcinoma in the investigation of issues within Cancer research. His Chromosomal translocation research incorporates elements of Gene rearrangement, Pathogenesis, Marker chromosome, Sarcoma and Lymphoma. His research in Cytogenetics intersects with topics in Gene duplication, Soft tissue, Comparative genomic hybridization and Surgical pathology.

His most cited work include:

  • Hypermutation of multiple proto-oncogenes in B-cell diffuse large-cell lymphomas (847 citations)
  • A manyfold increase in sister chromatid exchanges in Bloom's syndrome lymphocytes. (777 citations)
  • The BCL-6 proto-oncogene controls germinal-centre formation and Th2-type inflammation (714 citations)

What are the main themes of his work throughout his whole career to date?

R. S. K. Chaganti spends much of his time researching Molecular biology, Genetics, Gene, Cancer research and Pathology. His Molecular biology research is multidisciplinary, relying on both Chromosomal translocation, Southern blot and Fluorescence in situ hybridization, Chromosome, Gene mapping. In his research on the topic of Chromosomal translocation, B cell and Large cell is strongly related with Lymphoma.

R. S. K. Chaganti usually deals with Gene and limits it to topics linked to BCL6 and Promoter. His Pathology research is multidisciplinary, incorporating perspectives in Cancer, Karyotype, Cytogenetics, Germ cell and Germ cell tumors. His work carried out in the field of Cytogenetics brings together such families of science as Gene duplication and Non-Hodgkin's lymphoma.

He most often published in these fields:

  • Molecular biology (38.86%)
  • Genetics (27.01%)
  • Gene (25.59%)

What were the highlights of his more recent work (between 2003-2016)?

  • Cancer research (22.27%)
  • Molecular biology (38.86%)
  • Gene expression profiling (4.74%)

In recent papers he was focusing on the following fields of study:

His main research concerns Cancer research, Molecular biology, Gene expression profiling, Pathology and Internal medicine. R. S. K. Chaganti has researched Cancer research in several fields, including Cancer, Targeted therapy, Metastasis, Diffuse large B-cell lymphoma and Alpha interferon. His study in Molecular biology is interdisciplinary in nature, drawing from both Cell culture, Gene, Cell growth and Lymphoma.

Genetics covers R. S. K. Chaganti research in Gene. His Pathology research includes elements of Cell of origin and Loss of heterozygosity. His Internal medicine research incorporates themes from Oncology and Germ cell.

Between 2003 and 2016, his most popular works were:

  • Targeted Therapy for Metastatic Renal Cell Carcinoma (386 citations)
  • Down-Regulation of Stem Cell Genes, Including Those in a 200-kb Gene Cluster at 12p13.31, Is Associated with In vivo Differentiation of Human Male Germ Cell Tumors (245 citations)
  • Gene dosage alterations revealed by cDNA microarray analysis in cervical cancer: Identification of candidate amplified and overexpressed genes (150 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Cancer
  • DNA

His primary areas of study are Cancer research, Molecular biology, Sunitinib, Renal cell carcinoma and Gene. His biological study spans a wide range of topics, including Genetic screen, Follicular lymphoma, Transplantation and Suppressor. R. S. K. Chaganti combines subjects such as Stromal cell, Cell growth, Cancer cell, Interleukin 8 and CXCL5 with his study of Molecular biology.

His research investigates the connection between Sunitinib and topics such as Kidney cancer that intersect with problems in Erlotinib, Bevacizumab, Targeted therapy and Alpha interferon. As part of his studies on Gene, R. S. K. Chaganti often connects relevant subjects like Lymphoma. His Gene dosage research entails a greater understanding of Genetics.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

A manyfold increase in sister chromatid exchanges in Bloom's syndrome lymphocytes.

R. S. K. Chaganti;S. Schonberg;James German.
Proceedings of the National Academy of Sciences of the United States of America (1974)

1221 Citations

Hypermutation of multiple proto-oncogenes in B-cell diffuse large-cell lymphomas

Laura Pasqualucci;Peter Neumeister;Tina Goossens;Gouri Nanjangud.
Nature (2001)

1158 Citations

The BCL-6 proto-oncogene controls germinal-centre formation and Th2-type inflammation

Bihui H. Ye;Giorgio Cattoretti;Qiong Shen;Jiandong Zhang.
Nature Genetics (1997)

927 Citations

Alterations of a Zinc Finger-Encoding Gene, BCL-6, in Diffuse Large-Cell Lymphoma

B. H. Ye;F. Lista;F. Lo Coco;F. Lo Coco;D. M. Knowles.
Science (1993)

788 Citations

Rearrangement of the MLL Gene in Acute Lymphoblastic and Acute Myeloid Leukemias with 11q23 Chromosomal Translocations

Michael J. Thirman;Heidi J. Gill;Robert C. Burnett;David Mbangkollo.
The New England Journal of Medicine (1993)

706 Citations

Targeted Therapy for Metastatic Renal Cell Carcinoma

P H Patel;R S K Chaganti;R J Motzer.
Journal of Clinical Oncology (2006)

600 Citations

BCL-6 mutations in normal germinal center B cells: Evidence of somatic hypermutation acting outside Ig loci

Laura Pasqualucci;Anna Migliazza;Nicola Fracchiolla;Christopher William.
Proceedings of the National Academy of Sciences of the United States of America (1998)

580 Citations

A Common Molecular Basis for Rearrangement Disorders on Chromosome 22q11

Lisa Edelmann;Raj K. Pandita;Elizabeth Spiteri;Birgit Funke.
Human Molecular Genetics (1999)

520 Citations

BCL-6, a POZ/zinc-finger protein, is a sequence-specific transcriptional repressor

Chih Chao Chang;Bihui H. Ye;R. S.K. Chaganti;Riccardo Dalla-Favera.
Proceedings of the National Academy of Sciences of the United States of America (1996)

508 Citations

B cell lymphoma-associated chromosomal translocation involves candidate oncogene lyt-10, homologous to NF-κB p50

Antonino Neri;Antonino Neri;Chih Chao Chang;Luigia Lombardi;Mauro Salina.
Cell (1991)

478 Citations

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