Protul Shrikant

Best Publications

• Tumor-infiltrating NY-ESO-1–specific CD8+ T cells are negatively regulated by LAG-3 and PD-1 in human ovarian cancer

  Junko Matsuzaki;Sacha Gnjatic;Paulette Mhawech-Fauceglia;Amy Beck

  997
  Citations

• The mTOR Kinase Determines Effector versus Memory CD8+ T Cell Fate by Regulating the Expression of Transcription Factors T-bet and Eomesodermin

  Rajesh R. Rao;Qingsheng Li;Kunle Odunsi;Protul A. Shrikant

  696
  Citations

• CTLA-4 blockade reverses CD8+ T cell tolerance to tumor by a CD4+ T cell- and IL-2-dependent mechanism.

  Protul Shrikant;Alexander Khoruts;Matthew F Mescher

  358
  Citations

• IL-21 Enhances and Sustains CD8+ T Cell Responses to Achieve Durable Tumor Immunity: Comparative Evaluation of IL-2, IL-15, and IL-21

  Adrianna Moroz;Cheryl Eppolito;Qingsheng Li;Jianming Tao

  324
  Citations

• Vaccination with an NY-ESO-1 peptide of HLA class I/II specificities induces integrated humoral and T cell responses in ovarian cancer

  Kunle Odunsi;Feng Qian;Junko Matsuzaki;Paulette Mhawech-Fauceglia

  318
  Citations

• Transcription Factor Foxo1 Represses T-bet-Mediated Effector Functions and Promotes Memory CD8+ T Cell Differentiation

  Rajesh R. Rao;Qingsheng Li;Melanie R. Gubbels Bupp;Protul A. Shrikant

  309
  Citations

• LAG3 and PD1 co-inhibitory molecules collaborate to limit CD8+ T cell signaling and dampen antitumor immunity in a murine ovarian cancer model

  Ruea Yea Huang;Cheryl Eppolito;Shashikant Lele;Protul Shrikant

  302
  Citations

• The central nervous system as an immunocompetent organ: role of glial cells in antigen presentation.

  Protul Shrikant;Etty N. Benveniste

  294
  Citations

• Efficacy of vaccination with recombinant vaccinia and fowlpox vectors expressing NY-ESO-1 antigen in ovarian cancer and melanoma patients

  Kunle Odunsi;Junko Matsuzaki;Julia Karbach;Antje Neumann

  214
  Citations

• Class I Histone Deacetylase Inhibitor Entinostat Suppresses Regulatory T Cells and Enhances Immunotherapies in Renal and Prostate Cancer Models

  Li Shen;Michael Ciesielski;Swathi Ramakrishnan;Kiersten M. Miles

  210
  Citations

• A Central Role for mTOR Kinase in Homeostatic Proliferation Induced CD8+ T Cell Memory and Tumor Immunity

  Qingsheng Li;Rajesh R. Rao;Koichi Araki;Kristen Pollizzi

  190
  Citations

• Efficacy of Levo-1-Methyl Tryptophan and Dextro-1-Methyl Tryptophan in Reversing Indoleamine-2,3-Dioxygenase–Mediated Arrest of T-Cell Proliferation in Human Epithelial Ovarian Cancer

  Feng Qian;Jeannine Villella;Paul K. Wallace;Paulette Mhawech-Fauceglia

  185
  Citations

• Control of Syngeneic Tumor Growth by Activation of CD8+ T Cells: Efficacy Is Limited by Migration Away from the Site and Induction of Nonresponsiveness

  Protul Shrikant;Matthew F. Mescher

  179
  Citations

• Cytokine-induced expression of vascular cell adhesion molecule-1 (VCAM-1) by astrocytes and astrocytoma cell lines.

  Stephen J. Rosenman;Protul Shrikant;Lindsey Dubb;Etty N. Benveniste

  172
  Citations

• The acute phase protein haptoglobin regulates host immunity.

  Kristin M. Huntoon;Yanping Wang;Cheryl A. Eppolito;Karen W. Barbour

  163
  Citations

• Regulation of intercellular adhesion molecule-1 gene expression by tumor necrosis factor-α, interleukin-1β, and interferon-γ in astrocytes

  Protul Shrikant;Il Yup Chung;Mary E. Ballestas;Etty N. Benveniste

  158
  Citations

• Intercellular adhesion molecule-1 gene expression by glial cells. Differential mechanisms of inhibition by IL-10 and IL-6.

  P Shrikant;E Weber;T Jilling;E N Benveniste

  145
  Citations

• HIV glycoprotein 120 enhances intercellular adhesion molecule-1 gene expression in glial cells. Involvement of Janus kinase/signal transducer and activator of transcription and protein kinase C signaling pathways.

  Protul Shrikant;Dale J. Benos;Li Ping Tang;Etty N. Benveniste

  129
  Citations

• Temsirolimus, an mTOR inhibitor, enhances anti-tumour effects of heat shock protein cancer vaccines

  Y. Wang;X.-Y. Wang;J. R. Subjeck;P. A. Shrikant

  124
  Citations

• The Shiga toxin B-subunit targets antigen in vivo to dendritic cells and elicits anti-tumor immunity.

  Benoit Vingert;Olivier Adotevi;Delphine Patin;Steffen Jung

  118
  Citations