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Marco Vignuzzi

Marco Vignuzzi

D-Index & Metrics

Microbiology

D-Index
56
Citations
18355
World Ranking
3655
National Ranking
213

Overview

Marco Vignuzzi is affiliated with the Institut Pasteur in France and has focused their research primarily on infectious diseases, molecular biology, and public health. Their work covers the fields of medicine as well as biochemistry, genetics, and molecular biology.

Their main topics of research include:

  • SARS-CoV-2 and COVID-19 Research
  • Mosquito-borne diseases and control
  • Insect symbiosis and bacterial influences
  • Viral Infections and Vectors
  • COVID-19 Clinical Research Studies
  • Viral Infections and Immunology Research
  • Plant Virus Research Studies

Marco Vignuzzi's work has been published in a variety of scientific journals, with frequent contributions to:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Science
  • Nature Communications
  • PLoS Pathogens
  • Journal of Virology

Some of their recent notable papers include:

  • "The Global Phosphorylation Landscape of SARS-CoV-2 Infection," 2020, Cell
  • "An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike," 2020, Science
  • "A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing," 2020, bioRxiv (Cold Spring Harbor Laboratory)
  • "Plitidepsin has potent preclinical efficacy against SARS-CoV-2 by targeting the host protein eEF1A," 2021, Science
  • "Masitinib is a broad coronavirus 3CL inhibitor that blocks replication of SARS-CoV-2," 2021, Science

Collaboration is a significant aspect of their research. Frequent coauthors include:

  • Thomas Vallet
  • Veronica V. Rezelj
  • Kris M. White
  • Adolfo García-Sastre
  • Nevan J. Krogan

Best Publications

  • A SARS-CoV-2 protein interaction map reveals targets for drug repurposing.

    David E. Gordon;Gwendolyn M. Jang;Mehdi Bouhaddou;Jiewei Xu

  • Quasispecies diversity determines pathogenesis through cooperative interactions in a viral population

    Marco Vignuzzi;Jeffrey K. Stone;Jamie J. Arnold;Craig E. Cameron

  • The Global Phosphorylation Landscape of SARS-CoV-2 Infection.

    Mehdi Bouhaddou;Danish Memon;Bjoern Meyer;Kris M. White

  • Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.

    David E. Gordon;Joseph Hiatt;Mehdi Bouhaddou;Veronica V. Rezelj

  • Coronaviruses Lacking Exoribonuclease Activity Are Susceptible to Lethal Mutagenesis: Evidence for Proofreading and Potential Therapeutics

    Everett Clinton Smith;Hervé Blanc;Marco Vignuzzi;Mark R. Denison

  • An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike

    Michael Schoof;Bryan Faust;Reuben A. Saunders;Smriti Sangwan

  • Curcumin inhibits Zika and chikungunya virus infection by inhibiting cell binding

    Bryan C. Mounce;Teresa Cesaro;Lucia Carrau;Thomas Vallet

  • Defective viral genomes are key drivers of the virus-host interaction.

    Marco Vignuzzi;Carolina B. López

  • Engineering attenuated virus vaccines by controlling replication fidelity

    Marco Vignuzzi;Emily Wendt;Raul Andino

  • Plitidepsin has potent preclinical efficacy against SARS-CoV-2 by targeting the host protein eEF1A.

    Kris M. White;Romel Rosales;Soner Yildiz;Thomas Kehrer

  • Evolutionary constraints on chaperone-mediated folding provide an antiviral approach refractory to development of drug resistance

    Ron Geller;Marco Vignuzzi;Raul Andino;Judith Frydman

  • Arbovirus high fidelity variant loses fitness in mosquitoes and mice

    Lark L. Coffey;Yasnee Beeharry;Yasnee Beeharry;Antonio V. Bordería;Hervé Blanc

  • Large-scale phylogenomic analysis reveals the complex evolutionary history of rabies virus in multiple carnivore hosts.

    Cécile Troupin;Laurent Dacheux;Marion Tanguy;Claude Sabeta

  • Masitinib is a broad coronavirus 3CL inhibitor that blocks replication of SARS-CoV-2.

    Nir Drayman;Jennifer K. DeMarco;Krysten A. Jones;Saara-Anne Azizi;Saara-Anne Azizi

  • Harnessing Endogenous miRNAs to Control Virus Tissue Tropism as a Strategy for Developing Attenuated Virus Vaccines

    Dwight Barnes;Mark Kunitomi;Marco Vignuzzi;Kalle Saksela

  • Virus-derived DNA drives mosquito vector tolerance to arboviral infection.

    Bertsy Goic;Kenneth A. Stapleford;Lionel Frangeul;Aurélien J. Doucet

  • Homology-Based Identification of a Mutation in the Coronavirus RNA-Dependent RNA Polymerase That Confers Resistance to Multiple Mutagens

    Nicole R. Sexton;Everett Clinton Smith;Hervé Blanc;Marco Vignuzzi

  • Drug-induced phospholipidosis confounds drug repurposing for SARS-CoV-2.

    Tia A. Tummino;Veronica V. Rezelj;Benoit Fischer;Audrey Fischer

  • Host Alternation of Chikungunya Virus Increases Fitness while Restricting Population Diversity and Adaptability to Novel Selective Pressures

    Lark L. Coffey;Marco Vignuzzi

  • Remote site control of an active site fidelity checkpoint in a viral RNA-dependent RNA polymerase.

    Jamie J. Arnold;Marco Vignuzzi;Jeffrey K. Stone;Raul Andino

  • Ribavirin and lethal mutagenesis of poliovirus: molecular mechanisms, resistance and biological implications.

    Marco Vignuzzi;Jeffrey K. Stone;Raul Andino

Frequent Co-Authors

Sylvie van der Werf
Sylvie van der Werf Université Paris Cité
Melanie Ott
Melanie Ott Gladstone Institutes
Nevan J. Krogan
Nevan J. Krogan University of California, San Francisco
Raul Andino
Raul Andino University of California, San Francisco
Adolfo García-Sastre
Adolfo García-Sastre Icahn School of Medicine at Mount Sinai
Kevan M. Shokat
Kevan M. Shokat University of California, San Francisco
Noam Shomron
Noam Shomron Tel Aviv University
Brian K. Shoichet
Brian K. Shoichet University of California, San Francisco
Etienne Simon-Loriere
Etienne Simon-Loriere Institut Pasteur
Craig E. Cameron
Craig E. Cameron University of North Carolina at Chapel Hill

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