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Lawrence A. Chasin

Lawrence A. Chasin

Columbia University
United States

D-Index & Metrics

Discipline name D-Index World Ranking Current World Ranking National Ranking Current National Ranking Publications Citations
Molecular Biology 45 2844 2584 1360 1221 88 10393

Lawrence A. Chasin publications per year

The chart shows the history of publications by Lawrence A. Chasin between 1963 and 2022, highlighting the no. of papers published in each year and offering an overview of the publication velocity of this scholar. Lawrence A. Chasin published across 60 years, from 1963 to 2022, averaging 1.6 papers a year. Output peaked at 6 publications in 1986. 3 of the 95 publications appeared in the last two years.

No. of publications
2 4 6
Bar chart. Horizontal axis: year, 1963 to 2022. Vertical axis: number of publications, 0 to 6. Peak 6 publications in 1986. 1963: 1 publication 1964: 0 publications 1965: 0 publications 1966: 0 publications 1967: 1 publication 1968: 1 publication 1969: 1 publication 1970: 1 publication 1971: 0 publications 1972: 1 publication 1973: 1 publication 1974: 2 publications 1975: 2 publications 1976: 1 publication 1977: 1 publication 1978: 2 publications 1979: 3 publications 1980: 1 publication 1981: 1 publication 1982: 1 publication 1983: 2 publications 1984: 0 publications 1985: 3 publications 1986: 6 publications 1987: 3 publications 1988: 4 publications 1989: 3 publications 1990: 3 publications 1991: 0 publications 1992: 2 publications 1993: 4 publications 1994: 1 publication 1995: 0 publications 1996: 1 publication 1997: 1 publication 1998: 2 publications 1999: 2 publications 2000: 2 publications 2001: 0 publications 2002: 1 publication 2003: 3 publications 2004: 4 publications 2005: 5 publications 2006: 1 publication 2007: 2 publications 2008: 2 publications 2009: 1 publication 2010: 3 publications 2011: 2 publications 2012: 0 publications 2013: 1 publication 2014: 0 publications 2015: 2 publications 2016: 2 publications 2017: 0 publications 2018: 1 publication 2019: 0 publications 2020: 2 publications 2021: 1 publication 2022: 2 publications
1963 2022

95 publications in total across all disciplines

View publications per year as a table
Lawrence A. Chasin: publications per year, 1963 to 2022
Year Publications
1963 1
1964 0
1965 0
1966 0
1967 1
1968 1
1969 1
1970 1
1971 0
1972 1
1973 1
1974 2
1975 2
1976 1
1977 1
1978 2
1979 3
1980 1
1981 1
1982 1
1983 2
1984 0
1985 3
1986 6
1987 3
1988 4
1989 3
1990 3
1991 0
1992 2
1993 4
1994 1
1995 0
1996 1
1997 1
1998 2
1999 2
2000 2
2001 0
2002 1
2003 3
2004 4
2005 5
2006 1
2007 2
2008 2
2009 1
2010 3
2011 2
2012 0
2013 1
2014 0
2015 2
2016 2
2017 0
2018 1
2019 0
2020 2
2021 1
2022 2
Total 95
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Lawrence A. Chasin publication distribution in Molecular Biology in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Molecular Biology in 2026. The highlighted bar marks where Lawrence A. Chasin sits on this spectrum.

No. of scientists
50 100 150
Bar chart with 53 bars. Horizontal axis: publications, 47–56 to 564+. Vertical axis: number of scientists, 0 to 177. Most scientists, 177, have 117–126 publications. The last bar groups every scientist with 564 publications or more. The highlighted bar, 87–96 publications, is where this scientist sits. 47–56 publications: 7 scientists 57–66 publications: 17 scientists 67–76 publications: 65 scientists 77–86 publications: 90 scientists 87–96 publications: 125 scientists 97–106 publications: 131 scientists 107–116 publications: 162 scientists 117–126 publications: 177 scientists 127–136 publications: 158 scientists 137–146 publications: 158 scientists 147–156 publications: 146 scientists 157–166 publications: 159 scientists 167–176 publications: 131 scientists 177–186 publications: 110 scientists 187–196 publications: 112 scientists 197–206 publications: 100 scientists 207–216 publications: 89 scientists 217–226 publications: 98 scientists 227–236 publications: 74 scientists 237–246 publications: 72 scientists 247–256 publications: 63 scientists 257–266 publications: 53 scientists 267–276 publications: 54 scientists 277–286 publications: 49 scientists 287–296 publications: 52 scientists 297–306 publications: 43 scientists 307–316 publications: 46 scientists 317–326 publications: 41 scientists 327–336 publications: 42 scientists 337–346 publications: 31 scientists 347–356 publications: 28 scientists 357–366 publications: 29 scientists 367–376 publications: 26 scientists 377–386 publications: 24 scientists 387–396 publications: 24 scientists 397–406 publications: 14 scientists 407–416 publications: 13 scientists 417–426 publications: 20 scientists 427–436 publications: 12 scientists 437–446 publications: 20 scientists 447–456 publications: 11 scientists 457–466 publications: 10 scientists 467–476 publications: 14 scientists 477–486 publications: 14 scientists 487–496 publications: 10 scientists 497–506 publications: 13 scientists 507–516 publications: 13 scientists 517–526 publications: 2 scientists 527–536 publications: 4 scientists 537–546 publications: 6 scientists 547–556 publications: 8 scientists 557–563 publications: 6 scientists 564+ publications: 100 scientists
47–56 publications 564+

This scientist: 88 publications — 7th percentile

7% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 564 publications or more.

View publications distribution as a table
Number of Molecular Biology scientists by publication count, Research.com 2026 ranking edition. Based on 3,076 ranked scientists.
Publications Scientists This scientist
47–56 7
57–66 17
67–76 65
77–86 90
87–96 125 88
97–106 131
107–116 162
117–126 177
127–136 158
137–146 158
147–156 146
157–166 159
167–176 131
177–186 110
187–196 112
197–206 100
207–216 89
217–226 98
227–236 74
237–246 72
247–256 63
257–266 53
267–276 54
277–286 49
287–296 52
297–306 43
307–316 46
317–326 41
327–336 42
337–346 31
347–356 28
357–366 29
367–376 26
377–386 24
387–396 24
397–406 14
407–416 13
417–426 20
427–436 12
437–446 20
447–456 11
457–466 10
467–476 14
477–486 14
487–496 10
497–506 13
507–516 13
517–526 2
527–536 4
537–546 6
547–556 8
557–563 6
564+ 100
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Lawrence A. Chasin D-index placement in Molecular Biology in 2026

The chart shows the D-index (discipline H-index) distribution of Molecular Biology scientists ranked by Research.com in 2026. The highlighted bar marks where Lawrence A. Chasin sits on this spectrum.

No. of scientists
25 50 75 100 125
Bar chart with 54 bars. Horizontal axis: D-Index, 40–41 to 145+. Vertical axis: number of scientists, 0 to 131. Most scientists, 131, have 64–65 D-Index. The last bar groups every scientist with 145 D-Index or more. The highlighted bar, 44–45 D-Index, is where this scientist sits. 40–41 D-Index: 36 scientists 42–43 D-Index: 101 scientists 44–45 D-Index: 115 scientists 46–47 D-Index: 121 scientists 48–49 D-Index: 118 scientists 50–51 D-Index: 130 scientists 52–53 D-Index: 106 scientists 54–55 D-Index: 116 scientists 56–57 D-Index: 113 scientists 58–59 D-Index: 129 scientists 60–61 D-Index: 120 scientists 62–63 D-Index: 105 scientists 64–65 D-Index: 131 scientists 66–67 D-Index: 95 scientists 68–69 D-Index: 97 scientists 70–71 D-Index: 106 scientists 72–73 D-Index: 83 scientists 74–75 D-Index: 89 scientists 76–77 D-Index: 77 scientists 78–79 D-Index: 70 scientists 80–81 D-Index: 73 scientists 82–83 D-Index: 60 scientists 84–85 D-Index: 48 scientists 86–87 D-Index: 45 scientists 88–89 D-Index: 50 scientists 90–91 D-Index: 31 scientists 92–93 D-Index: 51 scientists 94–95 D-Index: 43 scientists 96–97 D-Index: 38 scientists 98–99 D-Index: 39 scientists 100–101 D-Index: 41 scientists 102–103 D-Index: 29 scientists 104–105 D-Index: 33 scientists 106–107 D-Index: 35 scientists 108–109 D-Index: 20 scientists 110–111 D-Index: 38 scientists 112–113 D-Index: 19 scientists 114–115 D-Index: 28 scientists 116–117 D-Index: 13 scientists 118–119 D-Index: 23 scientists 120–121 D-Index: 16 scientists 122–123 D-Index: 15 scientists 124–125 D-Index: 11 scientists 126–127 D-Index: 21 scientists 128–129 D-Index: 7 scientists 130–131 D-Index: 13 scientists 132–133 D-Index: 14 scientists 134–135 D-Index: 17 scientists 136–137 D-Index: 9 scientists 138–139 D-Index: 8 scientists 140–141 D-Index: 16 scientists 142–143 D-Index: 7 scientists 144 D-Index: 7 scientists 145+ D-Index: 100 scientists
40–41 D-Index 145+

This scientist: 45 D-Index — 8th percentile

8% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 145 D-Index or more.

View D-Index distribution as a table
Number of Molecular Biology scientists by D-index, Research.com 2026 ranking edition. Based on 3,076 ranked scientists.
D-Index Scientists This scientist
40–41 36
42–43 101
44–45 115 45
46–47 121
48–49 118
50–51 130
52–53 106
54–55 116
56–57 113
58–59 129
60–61 120
62–63 105
64–65 131
66–67 95
68–69 97
70–71 106
72–73 83
74–75 89
76–77 77
78–79 70
80–81 73
82–83 60
84–85 48
86–87 45
88–89 50
90–91 31
92–93 51
94–95 43
96–97 38
98–99 39
100–101 41
102–103 29
104–105 33
106–107 35
108–109 20
110–111 38
112–113 19
114–115 28
116–117 13
118–119 23
120–121 16
122–123 15
124–125 11
126–127 21
128–129 7
130–131 13
132–133 14
134–135 17
136–137 9
138–139 8
140–141 16
142–143 7
144 7
145+ 100
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Overview

Lawrence A. Chasin is affiliated with Columbia University in the United States and has contributed to research predominantly in biochemistry, genetics, and molecular biology. Their work spans several subfields, including molecular biology and genetics, with a focus on mechanisms related to viral infectious diseases and gene expression in insects, CRISPR and genetic engineering, virus-based gene therapy research, as well as RNA and protein synthesis mechanisms.

Their recent scholarly output includes the following papers:

  • A doubly auxotrophic CHO-K1 cell line for the production of recombinant monoclonal antibodies, 2020, Biotechnology and Bioengineering
  • A multiauxotrophic CHO cell line for the rapid isolation of producers of diverse or high levels of recombinant proteins, 2022, Biotechnology and Bioengineering
  • Biotechnology and Bioengineering: Volume 119, Number 6, June 2022, 2022, Biotechnology and Bioengineering

Chasin's frequent coauthors are:

  • Zhimei Du
  • Qinghao Zhang
  • Luke Nelson
  • Steven Huhn
  • Bo Jiang

The primary venue for their publications is the journal Biotechnology and Bioengineering, where all their recent papers have appeared.

The main topics addressed in their research include:

  • Viral Infectious Diseases and Gene Expression in Insects
  • CRISPR and Genetic Engineering
  • Virus-based gene therapy research
  • RNA and protein synthesis mechanisms

Lawrence A. Chasin's contributions to molecular biology and genetics focus on developing novel cell lines for biotechnological applications, particularly related to recombinant protein production and gene editing techniques. Their research involves engineering Chinese hamster ovary (CHO) cells to optimize the production of monoclonal antibodies and recombinant proteins, reflecting an interest in both fundamental biology and applied biotechnology.

Best Publications

  • DNA-mediated transfer of the adenine phosphoribosyltransferase locus into mammalian cells

    Michael Wigler;Angel Pellicer;Saul Silverstein;Richard Axel

  • Isolation of Chinese hamster cell mutants deficient in dihydrofolate reductase activity

    Gail Urlaub;Lawrence A. Chasin

  • Computational definition of sequence motifs governing constitutive exon splicing

    Xiang H.-F. Zhang;Lawrence A. Chasin

  • Amplified dihydrofolate reductase genes are localized to a homogeneously staining region of a single chromosome in a methotrexate-resistant Chinese hamster ovary cell line

    Jack H. Nunberg;Randal J. Kaufman;Robert T. Schimke;Gail Urlaub

  • Nonsense mutations in the dihydrofolate reductase gene affect RNA processing.

    G Urlaub;P J Mitchell;C J Ciudad;L A Chasin

  • Effect of gamma rays at the dihydrofolate reductase locus: deletions and inversions

    Gail Urlaub;Pamela J. Mitchell;Emmanuel Kas;Lawrence A. Chasin

  • Multiple Splicing Defects in an Intronic False Exon

    Hanzhen Sun;Lawrence A. Chasin

  • Quantitative evaluation of all hexamers as exonic splicing elements

    Shengdong Ke;Shulian Shang;Sergey M. Kalachikov;Irina Morozova

  • Searching for splicing motifs.

    Lawrence A Chasin

  • Point mutation analysis in a mammalian gene: rapid preparation of total RNA, PCR amplification of cDNA, and Taq sequencing by a novel method.

    A M Carothers;G Urlaub;J Mucha;D Grunberger

  • Genetics of somatic mammalian cells. X. Complementation analysis of glycine-requiring mutants.

    Fa-Ten Kao;Lawrence Chasin;Theodore T. Puck

  • Induction and Repression of the Histidine-degrading Enzymes of Bacillus subtilis

    Lawrence A. Chasin;Boris Magasanik

  • Sequence Information for the Splicing of Human Pre-mRNA Identified by Support Vector Machine Classification

    Xiang H.-F. Zhang;Katherine A. Heller;Ilana Hefter;Christina S. Leslie

  • Comparison of multiple vertebrate genomes reveals the birth and evolution of human exons

    Xiang H.-F. Zhang;Lawrence A. Chasin

  • Multiple transcription start sites, DNase I-hypersensitive sites, and an opposite-strand exon in the 5' region of the CHO dhfr gene.

    P J Mitchell;A M Carothers;J H Han;J D Harding

  • The effect of ploidy on chemical mutagenesis in cultured Chinese hamster cells.

    Lawrence A. Chasin

  • Dynamic Regulation of Alternative Splicing by Silencers that Modulate 5′ Splice Site Competition

    Yang Yu;Patricia A. Maroney;John A. Denker;Xiang H.-F. Zhang

  • Exon inclusion is dependent on predictable exonic splicing enhancers.

    Xiang H.-F. Zhang;Thaned Kangsamaksin;Mann S. P. Chao;Joydeep K. Banerjee

  • Human Genomic Sequences That Inhibit Splicing

    William G. Fairbrother;Lawrence A. Chasin

  • Mutations affecting adenine phosphoribosyl transferase activity in Chinese hamster cells

    Lawrence A. Chasin

Frequent Co-Authors

Xiang Zhang
Xiang Zhang University of Hong Kong
Christina S. Leslie
Christina S. Leslie Memorial Sloan Kettering Cancer Center
Zhaohui Feng
Zhaohui Feng Rutgers, The State University of New Jersey
Boris Magasanik
Boris Magasanik MIT
Jingyue Ju
Jingyue Ju Columbia University
Saul Silverstein
Saul Silverstein Columbia University
Theodore T. Puck
Theodore T. Puck Roosevelt Institute
Randal J. Kaufman
Randal J. Kaufman Sanford Burnham Prebys Medical Discovery Institute
Jacqueline K. Barton
Jacqueline K. Barton California Institute of Technology
Michael Wigler
Michael Wigler Cold Spring Harbor Laboratory

External Links

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Best Scientists Citing Lawrence A. Chasin

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Publications: 29

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Publications: 27

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Publications: 24

Christopher B. Burge

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MIT

Publications: 23

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Florian M. Wurm

École Polytechnique Fédérale de Lausanne

Publications: 23

Robert T. Schimke

Robert T. Schimke

Stanford University

Publications: 23

John A. McGrath

John A. McGrath

King's College London

Publications: 21

Louis Siminovitch

Louis Siminovitch

University of Toronto

Publications: 21

Mitsuo Satoh

Mitsuo Satoh

Kyowa Kirin (Japan)

Publications: 20

Kenya Shitara

Kenya Shitara

Kyowa Kirin (Japan)

Publications: 20

Igor Vorechovsky

Igor Vorechovsky

University of Southampton

Publications: 19

Akio Adachi

Akio Adachi

Kansai Medical University

Publications: 19

Chi-Huey Wong

Chi-Huey Wong

Scripps Research Institute

Publications: 19

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International Centre for Genetic Engineering and Biotechnology

Publications: 18

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Publications: 17

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