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Biology and Biochemistry

D-Index
85
Citations
23800
World Ranking
3178
National Ranking
1603

Overview

Rosalind A. Coleman is affiliated with the University of North Carolina at Chapel Hill in the United States. Their research spans multiple areas within biochemistry, genetics, and molecular biology, with significant contributions to medicine as well.

The scientist's main fields of study include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Within these broader fields, the subfields of particular focus are:

  • Molecular Biology
  • Biochemistry
  • Physiology
  • Clinical Biochemistry
  • Cancer Research

The topics of work undertaken cover a range of biological and metabolic processes, including:

  • Lipid metabolism and biosynthesis
  • Peroxisome Proliferator-Activated Receptors
  • Metabolomics and Mass Spectrometry Studies
  • Adipose Tissue and Metabolism
  • Microbial Metabolic Engineering and Bioproduction
  • Metabolism and Genetic Disorders
  • Diet, Metabolism, and Disease

Rosalind A. Coleman has published extensively, with notable papers including:

  • PLIN5 interacts with FATP4 at membrane contact sites to promote lipid droplet-to-mitochondria fatty acid transport, 2023, Developmental Cell
  • The "discovery" of lipid droplets: A brief history of organelles hidden in plain sight, 2020, Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
  • Unique Regulation of Adipose Triglyceride Lipase (ATGL) by Perilipin 5, a Lipid Droplet-associated Protein, 2020, UNC Libraries
  • Expression and Characterization of Recombinant Rat Acyl-CoA Synthetases 1, 4, and 5: SELECTIVE INHIBITION BY TRIACSIN C AND THIAZOLIDINEDIONES, 2021, UNC Libraries
  • Triacylglycerol synthesis directed by glycerol-3-phosphate acyltransferases −3 and −4 is required for lipid droplet formation and the modulation of the inflammatory response during macrophage to foam cell transition, 2020, Atherosclerosis

The scientist has collaborated frequently with several researchers, including:

  • Eric L. Klett
  • Tal M. Lewin
  • Lei O. Li
  • Deborah M. Muoio
  • Trisha J. Grevengoed

Rosalind A. Coleman has contributed a substantial body of work published in a variety of venues, most notably:

  • UNC Libraries
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Developmental Cell
  • Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
  • Atherosclerosis

Best Publications

  • Enzymes of triacylglycerol synthesis and their regulation

    Rosalind A Coleman;Douglas P Lee

  • Enzymes of glycerolipid synthesis in eukaryotes.

    Robert M Bell;Rosalind A. Coleman

  • Triacylglycerol Synthesis Enzymes Mediate Lipid Droplet Growth by Relocalizing from the ER to Lipid Droplets

    Florian Wilfling;Huajin Wang;Joel T. Haas;Natalie Krahmer

  • The role of lipid droplets in metabolic disease in rodents and humans

    Andrew S. Greenberg;Rosalind A. Coleman;Fredric B. Kraemer;James L. McManaman

  • AMP-activated kinase reciprocally regulates triacylglycerol synthesis and fatty acid oxidation in liver and muscle: evidence that sn-glycerol-3-phosphate acyltransferase is a novel target.

    Deborah M. Muoio;Kimberly Seefeld;Lee A. Witters;Rosalind A. Coleman

  • Physiological and nutritional regulation of enzymes of triacylglycerol synthesis.

    Rosalind A. Coleman;Tal M. Lewin;Deborah M. Muoio

  • Acyl-CoA metabolism and partitioning.

    Trisha J. Grevengoed;Eric Leighton Klett;Rosalind A Coleman

  • Analysis of amino acid motifs diagnostic for the sn-glycerol-3-phosphate acyltransferase reaction.

    Tal M. Lewin;Ping Wang;Rosalind A. Coleman

  • Acyl-CoA synthetase isoforms 1, 4, and 5 are present in different subcellular membranes in rat liver and can be inhibited independently.

    Tal M. Lewin;Ji Hyeon Kim;Deborah A. Granger;Jean E. Vance

  • Do Long-Chain Acyl-CoA Synthetases Regulate Fatty Acid Entry into Synthetic Versus Degradative Pathways?

    Rosalind A. Coleman;Tal M. Lewin;Cynthia G. Van Horn;Maria R. Gonzalez-Baró

  • Adipose Acyl-CoA Synthetase-1 Directs Fatty Acids toward β-Oxidation and Is Required for Cold Thermogenesis

    Jessica M. Ellis;Lei O. Li;Pei Chi Wu;Timothy R. Koves

  • Prevention of hepatic steatosis and hepatic insulin resistance in mitochondrial acyl-CoA:glycerol-sn-3-phosphate acyltransferase 1 knockout mice.

    Susanne Neschen;Katsutaro Morino;Linda E. Hammond;Dongyan Zhang

  • Glycerol-3-phosphate acyltransferases: Rate limiting enzymes of triacylglycerol biosynthesis

    Angela A. Wendel;Tal M. Lewin;Rosalind A. Coleman

  • Hepatic triacylglycerol accumulation and insulin resistance

    Cynthia A. Nagle;Eric Leighton Klett;Rosalind A Coleman

  • Expression and Characterization of Recombinant Rat Acyl-CoA Synthetases 1, 4, and 5 SELECTIVE INHIBITION BY TRIACSIN C AND THIAZOLIDINEDIONES

    Ji Hyeon Kim;Tal M. Lewin;Rosalind A. Coleman

  • Diabetes promotes an inflammatory macrophage phenotype and atherosclerosis through acyl-CoA synthetase 1

    Jenny E. Kanter;Farah Kramer;Shelley Barnhart;Michelle M. Averill

  • Unique Regulation of Adipose Triglyceride Lipase (ATGL) by Perilipin 5, a Lipid Droplet-associated Protein

    Hong Wang;Ming Bell;Urmilla Sreenevasan;Hong Hu

  • Mammalian triacylglycerol metabolism: synthesis, lipolysis, and signaling

    Rosalind A. Coleman;Douglas G. Mashek

  • Acyl-CoA synthesis, lipid metabolism and lipotoxicity.

    Lei O. Li;Eric Leighton Klett;Rosalind A Coleman

  • Glycogen Storage Disease in Adults

    Gregg M. Talente;Rosalind A Coleman;Craig Alter;Lester Baker

Frequent Co-Authors

Deborah M. Muoio
Deborah M. Muoio Duke University
Yuan-Tsong Chen
Yuan-Tsong Chen Harbor–UCLA Medical Center
Gerald I. Shulman
Gerald I. Shulman Yale University
Gary W. Cline
Gary W. Cline Yale University
Donna D. Baird
Donna D. Baird National Institutes of Health
David A. Savitz
David A. Savitz Brown University
Olga Ilkayeva
Olga Ilkayeva Duke University
Clarice R. Weinberg
Clarice R. Weinberg National Institutes of Health
Christopher B. Newgard
Christopher B. Newgard Duke University
Andrew S. Greenberg
Andrew S. Greenberg Tufts University

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