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Medicine

D-Index
102
Citations
42106
World Ranking
7608
National Ranking
3962

Overview

Keith L. Black is affiliated with Cedars-Sinai Medical Center in the United States and has contributed extensively to the field of medicine, particularly focusing on neurodegenerative and ocular disorders. Their research spans multiple subfields including radiology, nuclear medicine and imaging, ophthalmology, physiology, molecular biology, and neurology. The primary emphasis lies on studying disease mechanisms and diagnostic techniques through advanced imaging and molecular methods.

The scientist's recent publications highlight a strong focus on Alzheimer's disease pathology in retinal tissue as well as glioma diagnosis and treatment. Notable papers include:

  • Identification of early pericyte loss and vascular amyloidosis in Alzheimer's disease retina, 2020, Acta Neuropathologica
  • Retinal pathological features and proteome signatures of Alzheimer's disease, 2023, Acta Neuropathologica
  • Alzheimer's Retinopathy: Seeing Disease in the Eyes, 2020, Frontiers in Neuroscience
  • Retinal Vasculopathy in Alzheimer's Disease, 2021, Frontiers in Neuroscience
  • Near Infrared Fluorescent Nanoplatform for Targeted Intraoperative Resection and Chemotherapeutic Treatment of Glioblastoma, 2020, ACS Nano

The research topics covered incorporate:

  • Retinal imaging and analysis
  • Alzheimer's disease research and treatments
  • Glaucoma and retinal disorders
  • Neuroinflammation and neurodegeneration mechanisms
  • Glioma diagnosis and treatment
  • Nanoplatforms for cancer theranostics
  • Tryptophan and brain disorders

Collaborative work is a significant aspect of their research output, with frequent co-authors including:

  • Maya Koronyo-Hamaoui
  • Yosef Koronyo
  • Dieu-Trang Fuchs
  • Altan Rentsendorj
  • Julia Sheyn

Keith L. Black has published regularly in a range of scientific journals. The most frequent venues include:

  • Alzheimer s & Dementia
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Acta Neuropathologica Communications
  • Research Square (Research Square)
  • Neuro-Oncology

The scope of Black's work integrates clinical imaging with molecular and physiological studies to advance understanding of neurological and retinal diseases. Research efforts aim at elucidating disease mechanisms while developing diagnostic and therapeutic strategies, especially related to Alzheimer's disease and glioma.

Best Publications

  • The Somatic Genomic Landscape of Glioblastoma

    Cameron W. Brennan;Roel G W Verhaak;Aaron McKenna;Benito Campos

  • Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma.

    Gentao Liu;Gentao Liu;Xiangpeng Yuan;Zhaohui Zeng;Patrizia Tunici

  • Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma.

    Michele Ceccarelli;Floris P Barthel;Tathiane M Malta;Thais S Sabedot

  • Isolation of cancer stem cells from adult glioblastoma multiforme

    Xiangpeng Yuan;James Curtin;Yizhi Xiong;Gentao Liu

  • Identification of amyloid plaques in retinas from Alzheimer's patients and noninvasive in vivo optical imaging of retinal plaques in a mouse model

    Maya Koronyo-Hamaoui;Yosef Koronyo;Alexander V. Ljubimov;Carol A. Miller

  • Interstitial chemotherapy with drug polymer implants for the treatment of recurrent gliomas.

    Brem H;Mahaley Ms;Vick Na;Black Kl

  • Vaccination of Malignant Glioma Patients with Peptide-pulsed Dendritic Cells Elicits Systemic Cytotoxicity and Intracranial T-cell Infiltration

    John S. Yu;Christopher J. Wheeler;Paul M. Zeltzer;Han Ying

  • Vaccination with tumor lysate-pulsed dendritic cells elicits antigen-specific, cytotoxic T-cells in patients with malignant glioma.

    John S. Yu;Gentao Liu;Han Ying;William H. Yong

  • Phase II Study of Bevacizumab Plus Temozolomide During and After Radiation Therapy for Patients With Newly Diagnosed Glioblastoma Multiforme

    Albert Lai;Anh Tran;Phioanh L. Nghiemphu;Whitney B. Pope

  • Retinal amyloid pathology and proof-of-concept imaging trial in Alzheimer’s disease

    Yosef Koronyo;David Biggs;Ernesto Barron;David S. Boyer

  • Eradication of established intracranial rat gliomas by transforming growth factor beta antisense gene therapy

    Habib Fakhrai;Oliver Dorigo;Daniel L. Shawler;Hong Lin

  • The use of interleukin 12-secreting neural stem cells for the treatment of intracranial glioma.

    Moneeb Ehtesham;Peter Kabos;Andrea Kabosova;Toomas Neuman

  • Phase I trial of a multi-epitope-pulsed dendritic cell vaccine for patients with newly diagnosed glioblastoma

    Surasak Phuphanich;Christopher J. Wheeler;Jeremy D. Rudnick;Mia Mazer

  • Induction of Glioblastoma Apoptosis Using Neural Stem Cell-mediated Delivery of Tumor Necrosis Factor-related Apoptosis-inducing Ligand

    Moneeb Ehtesham;Peter Kabos;Mervin A. R. Gutierrez;Nancy H. C. Chung

  • Vaccination elicits correlated immune and clinical responses in glioblastoma multiforme patients.

    Christopher J. Wheeler;Keith L. Black;Gentao Liu;Mia Mazer

  • Treatment of intracranial gliomas with bone marrow-derived dendritic cells pulsed with tumor antigens.

    Linda M. Liau;Keith L. Black;Robert M. Prins;Steven N. Sykes

  • Clinical Responsiveness of Glioblastoma Multiforme to Chemotherapy after Vaccination

    Christopher J. Wheeler;Asha Das;Gentao Liu;John S. Yu

  • Preliminary experience with MR-guided thermal ablation of brain tumors

    Y Anzai;R Lufkin;A DeSalles;D R Hamilton

  • Use of thallium-201 SPECT to quantitate malignancy grade of gliomas.

    Keith L. Black;Randall A. Hawkins;Kenneth T. Kim;Donald P. Becker

  • The somatic genomic landscape of glioblastoma

    Cameron W. Brennan;Roel G. W. Verhaak;Aaron Mckenna;Benito Campos

Frequent Co-Authors

John Yu
John Yu Memorial Hospital of South Bend
Alexander V. Ljubimov
Alexander V. Ljubimov Cedars-Sinai Medical Center
H. Phillip Koeffler
H. Phillip Koeffler Cedars-Sinai Medical Center
Timothy F. Cloughesy
Timothy F. Cloughesy University of California, Los Angeles
Michal Schwartz
Michal Schwartz Weizmann Institute of Science
Neil A. Martin
Neil A. Martin University of California, Los Angeles
Bruno Dubois
Bruno Dubois Université Paris Cité
Arthur W. Toga
Arthur W. Toga University of Southern California
Julian T. Hoff
Julian T. Hoff University of Michigan–Ann Arbor
Nicola Toschi
Nicola Toschi University of Rome Tor Vergata

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