D-Index & Metrics Best Publications
Hiroyuki Miyoshi

Hiroyuki Miyoshi

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Molecular Biology D-index 64 Citations 19,095 172 World Ranking 1110 National Ranking 99

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Cancer

Molecular biology, Cell biology, Stem cell, Genetic enhancement and Cell culture are his primary areas of study. His work carried out in the field of Molecular biology brings together such families of science as Cancer research, Myeloid leukemia, Gene, Chromosomal translocation and Retinal. His Cell biology study integrates concerns from other disciplines, such as Genetics, Lymphocyte function-associated antigen 1, Cytotoxic T cell, Interleukin 12 and Naive T cell.

His Stem cell research incorporates elements of Embryonic stem cell, Adult stem cell and Transplantation. In his study, Developmental biology, Germline, Somatic cell and Genetically modified organism is inextricably linked to Viral vector, which falls within the broad field of Genetic enhancement. The study incorporates disciplines such as Cellular differentiation, Cell cycle progression, Multicellular organism, Cell nucleus and Genetically modified mouse in addition to Cell culture.

His most cited work include:

  • Visualizing Spatiotemporal Dynamics of Multicellular Cell-Cycle Progression (1484 citations)
  • Development of a Self-Inactivating Lentivirus Vector (1092 citations)
  • t(8;21) breakpoints on chromosome 21 in acute myeloid leukemia are clustered within a limited region of a single gene, AML1. (765 citations)

What are the main themes of his work throughout his whole career to date?

Hiroyuki Miyoshi mostly deals with Cell biology, Molecular biology, Stem cell, Cancer research and Viral vector. Hiroyuki Miyoshi interconnects Immunology, Embryonic stem cell, In vitro and Cellular differentiation in the investigation of issues within Cell biology. His Molecular biology research includes elements of Green fluorescent protein, Gene expression, Gene, Chromosomal translocation and Myeloid leukemia.

His Stem cell study combines topics from a wide range of disciplines, such as KOSR, Induced pluripotent stem cell and Transplantation. His study in Cancer research is interdisciplinary in nature, drawing from both Cell culture, Carcinogenesis, Cancer, Cancer stem cell and RNA interference. His Viral vector study also includes fields such as

  • Genetic enhancement which connect with Virology and Transduction,
  • Internal medicine which is related to area like Endocrinology.

He most often published in these fields:

  • Cell biology (35.52%)
  • Molecular biology (32.24%)
  • Stem cell (24.59%)

What were the highlights of his more recent work (between 2015-2021)?

  • Cell biology (35.52%)
  • Cancer research (22.40%)
  • Induced pluripotent stem cell (12.57%)

In recent papers he was focusing on the following fields of study:

Hiroyuki Miyoshi spends much of his time researching Cell biology, Cancer research, Induced pluripotent stem cell, Stem cell and Cellular differentiation. His Cell biology research is multidisciplinary, incorporating perspectives in Cerebellum and Apoptosis. His studies deal with areas such as Cancer, Cell culture, Homeobox protein NANOG, Ischemia and Neural stem cell as well as Cancer research.

His studies in Induced pluripotent stem cell integrate themes in fields like Reprogramming, Cancer immunotherapy, Viral vector, Suicide gene and Cytotoxic T cell. Hiroyuki Miyoshi is involved in the study of Stem cell that focuses on Progenitor cell in particular. His Transgene study also includes

  • Beta-actin and related Molecular biology,
  • Ubiquitin C which is related to area like Embryonic stem cell.

Between 2015 and 2021, his most popular works were:

  • RFWD3-Mediated Ubiquitination Promotes Timely Removal of Both RPA and RAD51 from DNA Damage Sites to Facilitate Homologous Recombination. (68 citations)
  • Fail-Safe System against Potential Tumorigenicity after Transplantation of iPSC Derivatives (54 citations)
  • Genetically Encoded Tools for Optical Dissection of the Mammalian Cell Cycle. (49 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Cancer

Hiroyuki Miyoshi focuses on Cancer research, Induced pluripotent stem cell, Cell biology, DNA damage and Cellular differentiation. The Cancer research study combines topics in areas such as Monoclonal, Cytotoxic T cell, CD8 and Cancer immunotherapy. His Cell biology study incorporates themes from Embryonic stem cell, DDB1 and Cell cycle.

His research in DNA damage intersects with topics in Chromatin, Molecular biology, Ubiquitin ligase and DNA replication. His Cellular differentiation research incorporates themes from TBX6, Somite, Progenitor cell, Paraxial mesoderm and Transplantation. The concepts of his Progenitor cell study are interwoven with issues in Haematopoiesis and DNA methylation.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Visualizing Spatiotemporal Dynamics of Multicellular Cell-Cycle Progression

Asako Sakaue-Sawano;Hiroshi Kurokawa;Toshifumi Morimura;Aki Hanyu.
Cell (2008)

2024 Citations

Development of a Self-Inactivating Lentivirus Vector

Hiroyuki Miyoshi;Ulrike Blömer;Masayo Takahashi;Fred H. Gage.
Journal of Virology (1998)

1489 Citations

t(8;21) breakpoints on chromosome 21 in acute myeloid leukemia are clustered within a limited region of a single gene, AML1.

Hiroyuki Miyoshi;Kimiko Shimizu;Tomoko Kozu;Nobuo Maseki.
Proceedings of the National Academy of Sciences of the United States of America (1991)

1231 Citations

Transduction of Human CD34+ Cells That Mediate Long-Term Engraftment of NOD/SCID Mice by HIV Vectors

Hiroyuki Miyoshi;Kent A. Smith;Donald E. Mosier;Inder M. Verma.
Science (1999)

817 Citations

Generation of transgenic non-human primates with germline transmission

Erika Sasaki;Hiroshi Suemizu;Akiko Shimada;Kisaburo Hanazawa.
Nature (2009)

726 Citations

The t(8;21) translocation in acute myeloid leukemia results in production of an AML1-MTG8 fusion transcript.

H Miyoshi;T Kozu;K Shimizu;K Enomoto.
The EMBO Journal (1993)

716 Citations

Stable and efficient gene transfer into the retina using an HIV-based lentiviral vector

Hiroyuki Miyoshi;Masayo Takahashi;Fred H. Gage;Inder M. Verma.
Proceedings of the National Academy of Sciences of the United States of America (1997)

709 Citations

Self-formation of functional adenohypophysis in three-dimensional culture

Hidetaka Suga;Taisuke Kadoshima;Maki Minaguchi;Masatoshi Ohgushi.
Nature (2011)

481 Citations

Generation of the AML1-EVI-1 fusion gene in the t(3;21)(q26;q22) causes blastic crisis in chronic myelocytic leukemia.

K. Mitani;S. Ogawa;T. Tanaka;H. Miyoshi.
The EMBO Journal (1994)

437 Citations

The runt domain identifies a new family of heterometric transcriptional regulators

Hiroshi Kagoshima;Katsuya Shigesada;Masanobu Satake;Yoshiaki Ito.
Trends in Genetics (1993)

400 Citations

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