Herbert Fleisch

Overview

Best Publications

• Bisphosphonates: mechanisms of action

  Herbert Fleisch

  1531
  Citations

• c-Fos: a Key Regulator of Osteoclast-Macrophage Lineage Determination and Bone Remodeling

  Agamemnon E. Grigoriadis;Zhao-Qi Wang;Marco G. Cecchini;Willy Hofstetter

  1461
  Citations

• Bisphosphonates: mechanisms of action.

  Gideon A. Rodan;Herbert A. Fleisch

  1309
  Citations

• Bisphosphonates. Pharmacology and use in the treatment of tumour-induced hypercalcaemic and metastatic bone disease.

  Herbert Fleisch

  831
  Citations

• Effect of ethane-1-hydroxy-1,1-diphosphonate (EHDP) and dichloromethylene diphosphonate (Cl 2 MDP) on the calcification and resorption of cartilage and bone in the tibial epiphysis and metaphysis of rats.

  R. Schenk;W. A. Merz;R. Mühlbauer;R. G. G. Russell

  697
  Citations

• Role of colony stimulating factor-1 in the establishment and regulation of tissue macrophages during postnatal development of the mouse

  M.G. Cecchini;M.G. Dominguez;S. Mocci;A. Wetterwald

  654
  Citations

• MACROPHAGE COLONY STIMULATING FACTOR RESTORES IN VIVO BONE RESORPTION IN THE OP/OP OSTEOPETROTIC MOUSE

  R. Felix;M.G. Cecchini;H. Fleisch

  645
  Citations

• Bisphosphonates act on rat bone resorption through the mediation of osteoblasts.

  M Sahni;H L Guenther;H Fleisch;P Collin

  586
  Citations

• Current use of bisphosphonates in oncology. International Bone and Cancer Study Group.

  Jean-Jacques Body;R. Bartl;Peter Burckhardt;P.D. Delmas

  505
  Citations

• The influence of pyrophosphate, condensed phosphates, phosphonates and other phosphate compounds on the dissolution of hydroxyapatite in vitro and on bone resorption induced by parathyroid hormone in tissue culture and in thyroparathyroidectomised rats.

  R. G. G. Russell;R. C. Mühlbauer;S. Bisaz;D. A. Williams

  472
  Citations

• Isolation from urine of pyrophosphate, a calcification inhibitor.

  Herbert Fleisch;Sylvia Bisaz

  463
  Citations

• Quantitative morphometric evaluation of the inhibitory activity of new aminobisphosphonates on bone resorption in the rat.

  R Schenk;P Eggli;H Fleisch;S Rosini

  445
  Citations

• Structure-activity relationships of various bisphosphonates

  H Shinoda;G Adamek;R Felix;H Fleisch

  433
  Citations

• Inhibitors and promoters of stone formation.

  Herbert Fleisch

  427
  Citations

• The pharmacology of bisphosphonates and new insights into their mechanisms of action

  R G G Russell;M J Rogers;J C Frith;S P Luckman;S P Luckman

  397
  Citations

• Bisphosphonates induce osteoblasts to secrete an inhibitor of osteoclast-mediated resorption

  C Vitté;H Fleisch;H L Guenther

  389
  Citations

• BM 21.0955, a potent new bisphosphonate to inhibit bone resorption.

  R.C. Mühlbauer;F. Bauss;R. Schenk;M. Janner

  373
  Citations

• Rapid publication: Impairment of macrophage colony‐stimulating factor production and lack of resident bone marrow macrophages in the osteopetrotic op/op Mouse

  R. Felix;M.G. Cecchini;W. Hofstetter;P.R. Elford

  372
  Citations

• Characterization and cloning of the E11 antigen, a marker expressed by rat osteoblasts and osteocytes.

  A. Wetterwald;W. Hofstetter;M.G. Cecchini;B. Lanske

  357
  Citations

• Inorganic pyrophosphate in plasma in normal persons and in patients with hypophosphatasia, osteogenesis imperfecta, and other disorders of bone

  R. G. G. Russell;S. Bisaz;A. Donath;D. B. Morgan

  337
  Citations