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D-Index & Metrics

Biology and Biochemistry

D-Index
60
Citations
11949
World Ranking
12035
National Ranking
5159

Research.com Recognitions

  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Gary L. Stiles is affiliated with Duke University in the United States. Their research primarily focuses on the fields of Biochemistry, Genetics and Molecular Biology as well as Neuroscience. Within these fields, specific subfields of study include Physiology, Molecular Biology, Endocrine and Autonomic Systems, and Cellular and Molecular Neuroscience.

Stiles' research covers several key topics, including:

  • Adenosine and Purinergic Signaling
  • Pharmacological Receptor Mechanisms and Effects
  • Neuroscience of respiration and sleep
  • Neuropeptides and Animal Physiology

The recent scholarly output of Gary L. Stiles includes three publications, all authored in collaboration with Bertil B. Fredholm and published in the venue IUPHAR/BPS Guide to Pharmacology CITE:

  • "Adenosine receptors in GtoPdb v.2021.2" (2021)
  • "Adenosine receptors in GtoPdb v.2023.1" (2023)
  • "Adenosine receptors in GtoPdb v.2025.4" (2025)

Frequent coauthors working alongside Stiles include:

  • Bertil B. Fredholm
  • Bruno G. Frenguelli
  • Rebecca Hills
  • Adriaan P. IJzerman
  • Kenneth A. Jacobson

Gary L. Stiles has contributed exclusively to IUPHAR/BPS Guide to Pharmacology CITE for their recent publications, with a total of three papers published in this venue.

Among professional distinctions, Stiles has been recognized as a Member of the Association of American Physicians.

Best Publications

  • Beta-adrenergic receptors: biochemical mechanisms of physiological regulation

    G. L. Stiles;M. G. Caron;R. J. Lefkowitz

  • Molecular cloning and characterization of an adenosine receptor: the A3 adenosine receptor.

    Qun-Yong Zhou;Chuanyu Li;Mark E. Olah;Robert A. Johnson

  • Adenosine Receptor Subtypes: Characterization and Therapeutic Regulation

    Mark E. Olah;Gary L. Stiles

  • Mechanisms of membrane-receptor regulation. Biochemical, physiological, and clinical insights derived from studies of the adrenergic receptors.

    Robert J. Lefkowitz;Marc G. Caron;Gary L. Stiles

  • Cloning, expression, and characterization of the unique bovine A1 adenosine receptor. Studies on the ligand binding site by site-directed mutagenesis.

    Mark E. Olah;Hongzu Ren;Jacek Ostrowski;Kenneth A. Jacobson

  • 2-Substitution of N6-benzyladenosine-5'-uronamides enhances selectivity for A3 adenosine receptors.

    Hea O. Kim;Xiao-duo Ji;Suhaib M. Siddiqi;Mark E. Olah

  • The role of receptor structure in determining adenosine receptor activity

    Mark E Olah;Gary L Stiles

  • Human cardiac beta-adrenergic receptors: subtype heterogeneity delineated by direct radioligand binding.

    Gary L. Stiles;Gary L. Stiles;Sabrina Taylor;Sabrina Taylor;Robert J. Lefkowitz;Robert J. Lefkowitz

  • 125I-4-aminobenzyl-5'-N-methylcarboxamidoadenosine, a high affinity radioligand for the rat A3 adenosine receptor.

    M E Olah;C Gallo-Rodriguez;K A Jacobson;G L Stiles

  • A Binding Site Model and Structure-Activity Relationships for the Rat A3 Adenosine Receptor

    P J van Galen;A H van Bergen;C Gallo-Rodriguez;N Melman

  • Heterologous desensitization of the inhibitory A1 adenosine receptor-adenylate cyclase system in rat adipocytes. Regulation of both Ns and Ni.

    W J Parsons;G L Stiles

  • A3-adenosine receptors: design of selective ligands and therapeutic prospects.

    Jacobson Ka;Kim Ho;Siddiqi Sm;Olah Me

  • Pharmacological characterization of novel A3 adenosine receptor-selective antagonists.

    Kenneth A. Jacobson;Kyung-Sun Park;Ji-Long Jiang;Yong-Chul Kim

  • Distinct Pathways of Desensitization of A1- and A2-Adenosine Receptors in DDT1 MF-2 Cells

    Vickram Ramkumar;Mark E. Olah;Kenneth A. Jacobson;Gary L. Stiles

  • Adenosine A1 and A2 receptors: Structure–function relationships

    Philip J. M. van Galen;Gary L. Stiles;George Michaels;Kenneth A. Jacobson

  • Adenosine receptors: structure, function and regulation

    Gary L. Stiles

  • Differential Interaction with and Regulation of Multiple G-proteins by the Rat A3 Adenosine Receptor

    Timothy M. Palmer;Thomas W. Gettys;Gary L. Stiles

  • A role for central A3-adenosine receptors: Mediation of behavioral depressant effects

    Kenneth A. Jacobson;Olga Nikodijević;Dan Shi;Carola Gallo-Rodriguez

  • Modification of the rat adipocyte A1 adenosine receptor-adenylate cyclase system during chronic exposure to an A1 adenosine receptor agonist: alterations in the quantity of GS alpha and Gi alpha are not associated with changes in their mRNAs.

    J P Longabaugh;J Didsbury;A Spiegel;G L Stiles

  • Missing steps in the STAIR case: a Translational Medicine perspective on the development of NXY-059 for treatment of acute ischemic stroke.

    Giora Z Feuerstein;Margaret M Zaleska;Michael Krams;Xinkang Wang

Frequent Co-Authors

Kenneth A. Jacobson
Kenneth A. Jacobson National Institutes of Health
Robert J. Lefkowitz
Robert J. Lefkowitz Duke University
Marc G. Caron
Marc G. Caron Duke University
John W. Daly
John W. Daly National Institutes of Health
Adriaan P. IJzerman
Adriaan P. IJzerman Leiden University
Jeffrey L. Benovic
Jeffrey L. Benovic Thomas Jefferson University
Yong Chul Kim
Yong Chul Kim Gwangju Institute of Science and Technology
Pier Giovanni Baraldi
Pier Giovanni Baraldi University of Ferrara
Markus M. Nöthen
Markus M. Nöthen University Hospital Bonn
Marcella Rietschel
Marcella Rietschel Heidelberg University

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