D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Molecular Biology D-index 62 Citations 22,612 193 World Ranking 1199 National Ranking 623

Overview

What is he best known for?

The fields of study Gangning Liang is best known for:

  • Gene
  • DNA
  • Epigenetics

His research brings together the fields of Bladder cancer and Genetics. Gangning Liang conducts interdisciplinary study in the fields of Gene and Cell biology through his research. He performs integrative study on Cell biology and Gene. His study connects Histone H3 and Gene expression. His research brings together the fields of Gene expression and Histone H3. His research links RNA-Directed DNA Methylation with DNA methylation. He undertakes multidisciplinary investigations into Cancer research and Carcinogenesis in his work. With his scientific publications, his incorporates both Carcinogenesis and Cancer research. He undertakes multidisciplinary investigations into Epigenetics and microRNA in his work.

His most cited work include:

  • Epigenetics in human disease and prospects for epigenetic therapy (2770 citations)
  • Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells (1217 citations)
  • DNA-Demethylating Agents Target Colorectal Cancer Cells by Inducing Viral Mimicry by Endogenous Transcripts (918 citations)

What are the main themes of his work throughout his whole career to date

His Internal medicine research spans across into areas like Oncology and Pathology. Gangning Liang performs integrative study on Pathology and Internal medicine. His study deals with a combination of Gene and Epigenetics of physical exercise. Gangning Liang performs integrative study on Genetics and Cell biology. In his work, Gangning Liang performs multidisciplinary research in Cell biology and Genetics. His research combines Epigenetics of physical exercise and Gene expression. Gangning Liang integrates DNA methylation and Cancer epigenetics in his studies. Gangning Liang conducts interdisciplinary study in the fields of Cancer epigenetics and Epigenetics through his research. He conducts interdisciplinary study in the fields of Epigenetics and CpG site through his works.

Gangning Liang most often published in these fields:

  • Gene (93.20%)
  • Genetics (85.44%)
  • Gene expression (78.64%)

What were the highlights of his more recent work (between 2018-2022)?

  • Gene (90.00%)
  • Genetics (60.00%)
  • Cancer (60.00%)

In recent works Gangning Liang was focusing on the following fields of study:

His work often combines Gene and Epigenome studies. In his works, he undertakes multidisciplinary study on Epigenome and Gene expression. He merges Gene expression with Histone methylation in his research. In his research, he performs multidisciplinary study on Histone methylation and Nucleosome. Gangning Liang performs integrative study on Nucleosome and Chromatosome. Gangning Liang undertakes multidisciplinary studies into Chromatosome and Linker DNA in his work. Gangning Liang conducts interdisciplinary study in the fields of Linker DNA and Histone through his works. He integrates many fields, such as Histone and Methyltransferase, in his works. He integrates many fields, such as Methyltransferase and Epigenetics of physical exercise, in his works.

Between 2018 and 2022, his most popular works were:

  • The Roles of Human DNA Methyltransferases and Their Isoforms in Shaping the Epigenome (116 citations)
  • Structure of nucleosome-bound DNA methyltransferases DNMT3A and DNMT3B (44 citations)
  • Activation of a Subset of Evolutionarily Young Transposable Elements and Innate Immunity Are Linked to Clinical Responses to 5-Azacytidine (23 citations)

In his most recent research, the most cited works focused on:

  • Gene
  • Epigenetics
  • DNA

Much of his study explores Gene expression relationship to RNA-Directed DNA Methylation. As part of his studies on RNA-Directed DNA Methylation, Gangning Liang frequently links adjacent subjects like DNA methylation. He performs integrative study on DNA methylation and Epigenomics. Gangning Liang undertakes interdisciplinary study in the fields of Epigenomics and Methyltransferase through his research. Gangning Liang integrates many fields, such as Methyltransferase and Epigenetics of physical exercise, in his works. He combines Epigenetics of physical exercise and Epigenetics in his research. Gangning Liang incorporates Epigenetics and CpG site in his studies. While working in this field, Gangning Liang studies both CpG site and Methylation. Gangning Liang combines Methylation and Histone in his studies.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Epigenetics in human disease and prospects for epigenetic therapy

Gerda Egger;Gangning Liang;Ana Aparicio;Peter A. Jones.
Nature (2004)

3884 Citations

Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells

Yoshimasa Saito;Gangning Liang;Gerda Egger;Jeffrey M. Friedman.
Cancer Cell (2006)

1630 Citations

The human DNA methyltransferases (DNMTs) 1, 3a and 3b: coordinate mRNA expression in normal tissues and overexpression in tumors.

Keith D. Robertson;Eva Uzvolgyi;Gangning Liang;Cathy Talmadge.
Nucleic Acids Research (1999)

1118 Citations

DNA-Demethylating Agents Target Colorectal Cancer Cells by Inducing Viral Mimicry by Endogenous Transcripts.

David Roulois;Helen Loo Yau;Helen Loo Yau;Rajat Singhania;Yadong Wang.
Cell (2015)

933 Citations

Gene Body Methylation Can Alter Gene Expression and Is a Therapeutic Target in Cancer

Xiaojing Yang;Han Han;Daniel D. De Carvalho;Daniel D. De Carvalho;Fides D. Lay.
Cancer Cell (2014)

895 Citations

Rethinking how DNA methylation patterns are maintained

Peter A. Jones;Gangning Liang.
Nature Reviews Genetics (2009)

860 Citations

Cooperativity between DNA methyltransferases in the maintenance methylation of repetitive elements.

Gangning Liang;Matilda F. Chan;Yoshitaka Tomigahara;Yvonne C. Tsai.
Molecular and Cellular Biology (2002)

646 Citations

DZNep is a global histone methylation inhibitor that reactivates developmental genes not silenced by DNA methylation

Tina Branscombe Miranda;Connie C. Cortez;Christine B. Yoo;Gangning Liang.
Molecular Cancer Therapeutics (2009)

630 Citations

Distinct localization of histone H3 acetylation and H3-K4 methylation to the transcription start sites in the human genome.

Gangning Liang;Joy C. Y. Lin;Vivian Wei;Christine Yoo.
Proceedings of the National Academy of Sciences of the United States of America (2004)

578 Citations

Histone H3-Lysine 9 Methylation Is Associated with Aberrant Gene Silencing in Cancer Cells and Is Rapidly Reversed by 5-Aza-2′-deoxycytidine

Carvell T. Nguyen;Daniel J. Weisenberger;Mihaela Velicescu;Felicidad A. Gonzales.
Cancer Research (2002)

486 Citations

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