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D-Index & Metrics

Biology and Biochemistry

D-Index
58
Citations
15168
World Ranking
13012
National Ranking
5547

Overview

Kimberly D. Siegmund is affiliated with the University of Southern California in the United States. Their research spans multiple disciplines, primarily focusing on biochemistry, genetics, molecular biology, and medicine.

The main fields in which they have published include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Siegmund's work further delves into specific subfields such as molecular biology, surgery, pulmonary and respiratory medicine, genetics, and oncology.

Their research covers a variety of scientific topics. The main areas of interest comprise:

  • Epigenetics and DNA Methylation
  • Bladder and Urothelial Cancer Treatments
  • Cancer Genomics and Diagnostics
  • Urinary and Genital Oncology Studies
  • Smoking Behavior and Cessation
  • Functional Brain Connectivity Studies
  • Advanced Neuroimaging Techniques and Applications

They have published research in several journals and venues, with frequent contributions to:

  • UNC Libraries
  • Nature Communications
  • Scientific Reports
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Clinical Oncology

Siegmund has collaborated extensively with a set of frequent co-authors including:

  • Loïc Le Marchand
  • Siamak Daneshmand
  • Paul Marjoram
  • Suhn K. Rhie
  • Darryl Shibata

Their recent publications highlight a range of research topics and methodologies. Selected papers include:

  • Inter-individual variability in structural brain development from late childhood to young adulthood, 2021, NeuroImage
  • The genome-wide impact of trisomy 21 on DNA methylation and its implications for hematopoiesis, 2021, Nature Communications
  • A novel role for vaping in mitochondrial gene dysregulation and inflammation fundamental to disease development, 2021, Scientific Reports
  • Cell-free DNA Methylation as a Predictive Biomarker of Response to Neoadjuvant Chemotherapy for Patients with Muscle-invasive Bladder Cancer in SWOG S1314, 2023, European Urology Oncology
  • DNA Methylation Profiles of Vegans and Non-Vegetarians in the Adventist Health Study-2 Cohort, 2020, Nutrients

Best Publications

  • CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer.

    Daniel J Weisenberger;Kimberly D Siegmund;Mihaela Campan;Joanne Young

  • A Big Bang model of human colorectal tumor growth

    Andrea Sottoriva;Haeyoun Kang;Zhicheng Ma;Trevor A Graham

  • Low-level processing of Illumina Infinium DNA Methylation BeadArrays

    Timothy J. Triche;Daniel J. Weisenberger;David Van Den Berg;Peter W. Laird

  • Lower Cancer Incidence in Amsterdam-I Criteria Families Without Mismatch Repair Deficiency: Familial Colorectal Cancer Type X

    Noralane M. Lindor;Kari Rabe;Gloria M. Petersen;Robert Haile

  • DNA Methylation in the Human Cerebral Cortex Is Dynamically Regulated throughout the Life Span and Involves Differentiated Neurons

    Kimberly D. Siegmund;Caroline M. Connor;Mihaela Campan;Tiffany I. Long

  • Genome-scale analysis of DNA methylation in lung adenocarcinoma and integration with mRNA expression

    Suhaida A. Selamat;Brian S. Chung;Luc Girard;Wei Zhang

  • Association of Breast Cancer DNA Methylation Profiles with Hormone Receptor Status and Response to Tamoxifen

    Martin Widschwendter;Kimberly D. Siegmund;Peter A. Jones;Peter W. Laird

  • Recommendations for the design and analysis of epigenome-wide association studies

    Karin B Michels;Alexandra M Binder;Sarah Dedeurwaerder;Charles B Epstein

  • Hypomethylation of a LINE-1 promoter activates an alternate transcript of the MET oncogene in bladders with cancer.

    Erika M. Wolff;Hyang-Min Byun;Han F. Han;Shikhar Sharma

  • Widespread epigenetic abnormalities suggest a broad DNA methylation erasure defect in abnormal human sperm

    Sahar Houshdaran;Victoria K. Cortessis;Kimberly D. Siegmund;Allen Yang

  • Environmental epigenetics: prospects for studying epigenetic mediation of exposure–response relationships

    Victoria K. Cortessis;Duncan C. Thomas;A. Joan Levine;Carrie V. Breton

  • Epigenetic profiling of somatic tissues from human autopsy specimens identifies tissue- and individual-specific DNA methylation patterns

    Hyang-Min Byun;Kimberly D. Siegmund;Fei Pan;Daniel J. Weisenberger

  • Bis-SNP: Combined DNA methylation and SNP calling for Bisulfite-seq data

    Yaping Liu;Kimberly D Siegmund;Peter W Laird;Benjamin P Berman

  • Detection of Methylated Apoptosis-Associated Genes in Urine Sediments of Bladder Cancer Patients

    Martin G. Friedrich;Daniel J. Weisenberger;Jonathan C. Cheng;Shahin Chandrasoma

  • Molecular characterization of MSI-H colorectal cancer by MLHI promoter methylation, immunohistochemistry, and mismatch repair germline mutation screening

    Jenny N. Poynter;Kimberly D. Siegmund;Daniel J. Weisenberger;Tiffany I. Long

  • Unique DNA methylation patterns distinguish noninvasive and invasive urothelial cancers and establish an epigenetic field defect in premalignant tissue.

    Erika M. Wolff;Yoshitomo Chihara;Fei Pan;Daniel J. Weisenberger

  • The PREMM1,2,6 Model Predicts Risk of MLH1, MSH2, and MSH6 Germline Mutations Based on Cancer History

    Fay Kastrinos;Ewout W. Steyerberg;Rowena Mercado;Judith Balmaña

  • Inferring clonal expansion and cancer stem cell dynamics from DNA methylation patterns in colorectal cancers

    Kimberly D. Siegmund;Paul Marjoram;Yen-Jung Woo;Simon Tavaré

  • The Methylenetetrahydrofolate Reductase 677C→T Polymorphism and Distal Colorectal Adenoma Risk

    A J Levine;K D Siegmund;C M Ervin;A Diep

  • Prognostic relevance of methylation markers in patients with non-muscle invasive bladder carcinoma

    Martin G. Friedrich;Martin G. Friedrich;Shahin Chandrasoma;Kimberly D. Siegmund;Daniel J. Weisenberger

Frequent Co-Authors

Peter W. Laird
Peter W. Laird Van Andel Institute
Daniel J. Weisenberger
Daniel J. Weisenberger University of Southern California
Gangning Liang
Gangning Liang University of Southern California
Peter A. Jones
Peter A. Jones Van Andel Institute
Robert W. Haile
Robert W. Haile Stanford University
Simon Tavaré
Simon Tavaré Columbia University
Frank D. Gilliland
Frank D. Gilliland University of Southern California
Loic Le Marchand
Loic Le Marchand University of Hawaii at Manoa
David V. Conti
David V. Conti University of Southern California
Hyang-Min Byun
Hyang-Min Byun Newcastle University

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