World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
61
Citations
35050
World Ranking
11085
National Ranking
4792

Overview

Andy J. Minn is affiliated with the University of Pennsylvania in the United States. Their research spans multiple fields with a focus on medicine, immunology and microbiology, and biochemistry, genetics, and molecular biology.

The scientist's work predominantly covers the following main fields of study:

  • Medicine
  • Immunology and Microbiology
  • Biochemistry, Genetics and Molecular Biology

Within these broader fields, they have contributed to several subfields:

  • Immunology
  • Oncology
  • Molecular Biology
  • Pulmonary and Respiratory Medicine
  • Cancer Research

The research topics that Andy J. Minn has worked on include:

  • Cancer Immunotherapy and Biomarkers
  • Immune cells in cancer
  • Immunotherapy and Immune Responses
  • Immune Cell Function and Interaction
  • CAR-T cell therapy research
  • Effects of Radiation Exposure
  • Interferon and immune responses

Andy J. Minn has published in several prominent scientific venues, with frequent publications in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancer Research
  • The Journal of Immunology
  • International Journal of Radiation Oncology*Biology*Physics
  • Nature Cancer

Some of their recent publications include:

  • Design, Implementation, and in Vivo Validation of a Novel Proton FLASH Radiation Therapy System, 2020, International Journal of Radiation Oncology*Biology*Physics
  • FLASH Proton Radiotherapy Spares Normal Epithelial and Mesenchymal Tissues While Preserving Sarcoma Response, 2021, Cancer Research
  • The immunostimulatory RNA RN7SL1 enables CAR-T cells to enhance autonomous and endogenous immune function, 2021, Cell
  • Combined JAK inhibition and PD-1 immunotherapy for non-small cell lung cancer patients, 2024, Science
  • Clinical and molecular features of acquired resistance to immunotherapy in non-small cell lung cancer, 2024, Cancer Cell

The scientist collaborates frequently with a group of peers, including:

  • E. John Wherry
  • Constantinos Koumenis
  • Amit Maity
  • Darwin Ye
  • Ioannis I. Verginadis

Best Publications

  • Tumour exosome integrins determine organotropic metastasis

    Ayuko Hoshino;Bruno Costa-Silva;Tang-Long Shen;Goncalo Rodrigues

  • Genes that mediate breast cancer metastasis to lung

    Andy J. Minn;Gaorav P. Gupta;Peter M. Siegel;Peter M. Siegel;Paula D. Bos

  • Radiation and dual checkpoint blockade activate non-redundant immune mechanisms in cancer

    Christina Twyman-Saint Victor;Andrew J. Rech;Amit Maity;Ramesh Rengan;Ramesh Rengan

  • Genes that mediate breast cancer metastasis to the brain

    Paula D. Bos;Xiang H.-F. Zhang;Cristina Nadal;Weiping Shu

  • Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis.

    Michael Sattler;Heng Liang;David Nettesheim;Robert P. Meadows

  • CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-xL

    Lawrence H. Boise;Andy J. Minn;Patricia J. Noel;Carl H. June

  • Mitotic progression following DNA damage enables pattern recognition within micronuclei

    Shane M. Harding;Joseph L. Benci;Jerome Irianto;Dennis E. Discher

  • Tumor Interferon Signaling Regulates a Multigenic Resistance Program to Immune Checkpoint Blockade.

    Joseph L. Benci;Bihui Xu;Yu Qiu;Tony J. Wu

  • Bcl-x(L) forms an ion channel in synthetic lipid membranes.

    Andy J. Minn;Patricio Vélez;Sharon L. Schendel;Heng Liang

  • Distinct organ-specific metastatic potential of individual breast cancer cells and primary tumors

    Andy J. Minn;Yibin Kang;Inna Serganova;Gaorav P. Gupta

  • Exosome Transfer from Stromal to Breast Cancer Cells Regulates Therapy Resistance Pathways

    Mirjam C. Boelens;Tony J. Wu;Barzin Y. Nabet;Bihui Xu

  • An interferon-related gene signature for DNA damage resistance is a predictive marker for chemotherapy and radiation for breast cancer

    Ralph R. Weichselbaum;Hemant Ishwaran;Taewon Yoon;Dimitry S. A. Nuyten

  • Combination Cancer Therapy with Immune Checkpoint Blockade: Mechanisms and Strategies.

    Shetal A. Patel;Andy J. Minn

  • Expression of Bcl-xL Can Confer a Multidrug Resistance Phenotype

    Andy J. Minn;Charles M. Rudin;Lawrence H. Boise;Craig B. Thompson

  • Opposing Functions of Interferon Coordinate Adaptive and Innate Immune Responses to Cancer Immune Checkpoint Blockade

    Joseph L. Benci;Lexus R. Johnson;Ruth Choa;Yuanming Xu

  • Lung metastasis genes couple breast tumor size and metastatic spread

    Andy J. Minn;Gaorav P. Gupta;David Padua;Paula Bos

  • High-Dimensional Variable Selection for Survival Data

    Hemant Ishwaran;Udaya B. Kogalur;Eiran Z. Gorodeski;Andy J. Minn

  • Raf kinase inhibitory protein suppresses a metastasis signalling cascade involving LIN28 and let‐7

    Surabhi Dangi-Garimella;Jieun Yun;Eva M Eves;Martin Newman

  • Identification of a novel regulatory domain in Bcl-X(L) and Bcl-2.

    Brian S. Chang;Andy J. Minn;Steven W. Muchmore;Stephen W. Fesik

  • Exosome RNA Unshielding Couples Stromal Activation to Pattern Recognition Receptor Signaling in Cancer

    Barzin Y. Nabet;Yu Qiu;Jacob E. Shabason;Tony J. Wu

Frequent Co-Authors

Robert H. Vonderheide
Robert H. Vonderheide University of Pennsylvania
Craig B. Thompson
Craig B. Thompson Memorial Sloan Kettering Cancer Center
E. John Wherry
E. John Wherry University of Pennsylvania
Lynn M. Schuchter
Lynn M. Schuchter University of Pennsylvania
Rosemarie Mick
Rosemarie Mick University of Pennsylvania
Lawrence H. Boise
Lawrence H. Boise Emory University
Joan Massagué
Joan Massagué Memorial Sloan Kettering Cancer Center
Ravi K. Amaravadi
Ravi K. Amaravadi University of Pennsylvania
Michael Feldman
Michael Feldman University of Pennsylvania
Stephen M. Hahn
Stephen M. Hahn The University of Texas Health Science Center at Houston

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