Eduardo López-Collazo

Overview

Best Publications

• Endotoxin tolerance: new mechanisms, molecules and clinical significance

  Subhra K. Biswas;Eduardo Lopez-Collazo

  1519
  Citations

• Autoantibodies neutralizing type I IFNs are present in ~ 4% of uninfected individuals over 70 years old and account for ~ 20% of COVID-19 deaths.

  Paul Bastard;Adrian Gervais;Adrian Gervais;Tom Le Voyer;Tom Le Voyer;Jérémie Rosain;Jérémie Rosain

  592
  Citations

• Human Monocytes Undergo Functional Re-programming during Sepsis Mediated by Hypoxia-Inducible Factor-1α

  Irina N. Shalova;Jyue Yuan Lim;Manesh Chittezhath;Annelies S. Zinkernagel

  434
  Citations

• Potent phagocytic activity with impaired antigen presentation identifying lipopolysaccharide-tolerant human monocytes: demonstration in isolated monocytes from cystic fibrosis patients.

  Carlos del Fresno;Francisco García-Rio;Vanesa Gómez-Piña;Alessandra Soares-Schanoski

  282
  Citations

• Metalloproteinases shed TREM-1 ectodomain from lipopolysaccharide-stimulated human monocytes.

  Vanesa Gómez-Piña;Alessandra Soares-Schanoski;Alexandro Rodríguez-Rojas;Carlos del Fresno

  261
  Citations

• Pathophysiology of endotoxin tolerance: mechanisms and clinical consequences.

  Eduardo López-Collazo;Carlos del Fresno

  229
  Citations

• Rapid up-regulation of IRAK-M expression following a second endotoxin challenge in human monocytes and in monocytes isolated from septic patients ☆

  Pedro Escoll;Carlos del Fresno;Lourdes Garcı́a;Gema Vallés

  227
  Citations

• WIP1 phosphatase is a negative regulator of NF-kappaB signalling.

  Joanne Chew;Subhra Biswas;Sathyavageeswaran Shreeram;Mahathir Humaidi

  209
  Citations

• Tumor Cells Deactivate Human Monocytes by Up-Regulating IL-1 Receptor Associated Kinase-M Expression via CD44 and TLR4

  Carlos del Fresno;Karel Otero;Lourdes Gómez-García;Maria Carmen González-León

  189
  Citations

• Role for MyD88-independent, TRIF pathway in lipid A/TLR4-induced endotoxin tolerance.

  Subhra K. Biswas;Pradeep Bist;Manprit Kaur Dhillon;Tasneem Kajiji

  141
  Citations

• Inherited BCL10 deficiency impairs hematopoietic and nonhematopoietic immunity

  Juan Manuel Torres;Rubén Martinez-Barricarte;Sonia García-Gómez;Marina S. Mazariegos

  115
  Citations

• Monocytes from cystic fibrosis patients are locked in an LPS tolerance state: down-regulation of TREM-1 as putative underlying mechanism.

  Carlos del Fresno;Vanesa Gómez-Piña;Vanesa Lores;Alessandra Soares-Schanoski

  114
  Citations

• Hypoxia-induced PD-L1/PD-1 crosstalk impairs T-cell function in sleep apnoea.

  Carolina Cubillos-Zapata;Jose Avendaño-Ortiz;Enrique Hernandez-Jimenez;Victor Toledano

  110
  Citations

• p21 mediates macrophage reprogramming through regulation of p50-p50 NF-κB and IFN-β

  Gorjana Rackov;Enrique Hernández-Jiménez;Rahman Shokri;Lorena Carmona-Rodríguez

  109
  Citations

• Sequential mechanisms of cyclophosphamide-induced skin allograft tolerance including the intrathymic clonal deletion followed by late breakdown of the clonal deletion.

  Masatoshi Eto;Hisanori Mayumi;Yukihiro Tomita;Yasunobu Yoshikai

  104
  Citations

• Triggering of peritoneal macrophages with IFN-alpha/beta attenuates the expression of inducible nitric oxide synthase through a decrease in NF-kappaB activation.

  Eduardo López-Collazo;Sonsoles Hortelano;Armando Rojas;Lisardo Boscá

  99
  Citations

• Immune Response and COVID-19: A mirror image of Sepsis.

  Eduardo López-Collazo;José Avendaño-Ortiz;Alejandro Martín-Quirós;Luis A Aguirre

  94
  Citations

• Protective effect of cyclosporin A and FK506 from nitric oxide-dependent apoptosis in activated macrophages.

  Sonsoles Hortelano;Eduardo López-Collazo;Lisardo Boscá

  89
  Citations

• Arabinoxylan rice bran (MGN-3/Biobran) enhances natural killer cell-mediated cytotoxicity against neuroblastoma in vitro and in vivo.

  Antonio Pérez-Martínez;Jaime Valentín;Lucía Fernández;Enrique Hernández-Jiménez

  88
  Citations

• Inflammatory responses associated with acute coronary syndrome up-regulate IRAK-M and induce endotoxin tolerance in circulating monocytes.

  Carlos del Fresno;Llanos Soler-Rangel;Alessandra Soares-Schanoski;Vanesa Gómez-Piña

  87
  Citations

• Biofilm vs. planktonic bacterial mode of growth: Which do human macrophages prefer?

  Enrique Hernández-Jiménez;Rosa del Campo;Victor Toledano;Maria Teresa Vallejo-Cremades

  84
  Citations

• A new IRAK-M-mediated mechanism implicated in the anti-inflammatory effect of nicotine via α7 nicotinic receptors in human macrophages.

  Maria C. Maldifassi;Gema Atienza;Francisco Arnalich;Eduardo López-Collazo

  78
  Citations

• Inflammatory cytokines and organ dysfunction associate with the aberrant DNA methylome of monocytes in sepsis.

  Clara Lorente-Sorolla;Antonio Garcia-Gomez;Francesc Català-Moll;Víctor Toledano

  76
  Citations