What is he best known for?
The fields of study he is best known for:
Christian Muchardt mainly investigates SWI/SNF, Transcription factor, Molecular biology, Cell biology and Chromatin.
He combines subjects such as RNA splicing, Spliceosome, Coding region, Exon and RNA polymerase II with his study of SWI/SNF.
His studies in Transcription factor integrate themes in fields like Regulation of gene expression and Cancer research.
His Molecular biology research incorporates elements of Embryonic stem cell, Histone H3, EZH2 and Heterochromatin, Heterochromatin protein 1.
His work carried out in the field of Cell biology brings together such families of science as Constitutive heterochromatin, Euchromatin, Non-histone protein, RNA-induced transcriptional silencing and Cell cycle.
He studies Chromatin remodeling which is a part of Chromatin.
His most cited work include:
- Purification and biochemical heterogeneity of the mammalian SWI-SNF complex. (694 citations)
- A human homologue of Saccharomyces cerevisiae SNF2/SWI2 and Drosophila brm genes potentiates transcriptional activation by the glucocorticoid receptor. (537 citations)
- The human SWI/SNF subunit Brm is a regulator of alternative splicing (392 citations)
What are the main themes of his work throughout his whole career to date?
Christian Muchardt focuses on Cell biology, Chromatin, Molecular biology, Transcription factor and Genetics.
His Cell biology research is multidisciplinary, incorporating perspectives in RNA, Transcription, Gene, Chromatin structure remodeling complex and RNA polymerase II.
His work on Chromatin remodeling and SWI/SNF is typically connected to Context as part of general Chromatin study, connecting several disciplines of science.
His research on Molecular biology also deals with topics like
- Heterochromatin protein 1, which have a strong connection to Histone H3, Histone code, EZH2 and Promoter,
- Cell cycle which intersects with area such as Homologous recombination and Cell growth.
Christian Muchardt has included themes like Regulation of gene expression and Cancer research in his Transcription factor study.
His Splicing factor research incorporates themes from Histone H2A, Histone methyltransferase and Histone H1.
He most often published in these fields:
- Cell biology (52.38%)
- Chromatin (42.86%)
- Molecular biology (38.10%)
What were the highlights of his more recent work (between 2017-2021)?
- Cell biology (52.38%)
- Gene (13.10%)
- Chromatin (42.86%)
In recent papers he was focusing on the following fields of study:
His main research concerns Cell biology, Gene, Chromatin, RNA and Alternative splicing.
In general Cell biology, his work in Extracellular is often linked to Listeria monocytogenes linking many areas of study.
In the subject of general Gene, his work in Heterochromatin is often linked to Cell type, thereby combining diverse domains of study.
Christian Muchardt interconnects Epigenetics, Neuroscience and DNA methylation in the investigation of issues within Chromatin.
His DNA methylation study combines topics in areas such as Multiple sclerosis, Histone H3, Disease and Gene silencing.
His Alternative splicing study integrates concerns from other disciplines, such as RNA polymerase II, Transcriptionally active chromatin and RNA splicing.
Between 2017 and 2021, his most popular works were:
- HIBISCUS: Hydroxychloroquine for the secondary prevention of thrombotic and obstetrical events in primary antiphospholipid syndrome. (35 citations)
- An RNA-Binding Protein Secreted by a Bacterial Pathogen Modulates RIG-I Signaling. (23 citations)
- Primary antiphospholipid syndrome and antiphospholipid syndrome associated to systemic lupus: Are they different entities? (12 citations)
In his most recent research, the most cited papers focused on:
Christian Muchardt mainly focuses on Primary antiphospholipid syndrome, Antiphospholipid syndrome, Cell biology, MEDLINE and In patient.
Christian Muchardt merges Cell biology with Endogenous retrovirus in his study.
His studies deal with areas such as Anticoagulant, Additional Therapy, Pediatrics and Orphan drug as well as MEDLINE.
In patient is integrated with Genetic data, Bioinformatics, Some limitation, Identification and Systemic lupus in his research.
Christian Muchardt undertakes multidisciplinary investigations into Genetic data and Systemic lupus erythematosus in his work.
Christian Muchardt brings together Hydroxychloroquine and Secondary prevention to produce work in his papers.
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