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Christian Muchardt

Christian Muchardt

D-Index & Metrics

Molecular Biology

D-Index
52
Citations
11492
World Ranking
2426
National Ranking
93

Overview

Christian Muchardt is affiliated with the Institut Pasteur in France, contributing to scientific research primarily in the fields of Biochemistry, Genetics and Molecular Biology, with a focus on Molecular Biology. Their work also intersects with Medicine and areas such as Immunology, Epidemiology, Cancer Research, and Public Health, Environmental and Occupational Health.

Their research extensively covers topics related to RNA, including:

  • RNA Research and Splicing
  • RNA modifications and cancer
  • RNA and protein synthesis mechanisms
  • RNA regulation and disease
  • Epigenetics and DNA Methylation
  • Cancer-related gene regulation
  • Influenza Virus Research Studies

Christian Muchardt has published multiple papers, some of which include:

  • "In utero exposure to Azathioprine in autoimmune disease. Where do we stand?", 2020, Autoimmunity Reviews
  • "HP1γ binding pre-mRNA intronic repeats modulates RNA splicing decisions", 2021, EMBO Reports
  • "Reduced RNA turnover as a driver of cellular senescence", 2021, Life Science Alliance
  • "CD44 alternative splicing senses intragenic DNA methylation in tumors via direct and indirect mechanisms", 2021, Nucleic Acids Research
  • "The Heterochromatin protein 1 is a regulator in RNA splicing precision deficient in ulcerative colitis", 2022, Nature Communications

Their frequent co-authors include:

  • Éric Batsché
  • Mickaël Costallat
  • Christophe Rachez
  • Étienne Kornobis
  • Jia Yi

Muchardt's work appears regularly in several scientific venues, including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Life Science Alliance
  • Nucleic Acids Research
  • Nature Communications
  • EMBO Reports

Best Publications

  • Purification and biochemical heterogeneity of the mammalian SWI-SNF complex.

    Weidong Wang;Jacques Côté;Yutong Xue;Sharleen Zhou

  • A human homologue of Saccharomyces cerevisiae SNF2/SWI2 and Drosophila brm genes potentiates transcriptional activation by the glucocorticoid receptor.

    C Muchardt;M Yaniv

  • The human SWI/SNF subunit Brm is a regulator of alternative splicing

    Eric Batsché;Moshe Yaniv;Christian Muchardt

  • Altered control of cellular proliferation in the absence of mammalian brahma (SNF2α)

    J. Reyes;J. Reyes;J. Barra;C. Muchardt;Anne Camus

  • The murine SNF5/INI1 chromatin remodeling factor is essential for embryonic development and tumor suppression.

    Agnes Klochendler-Yeivin;Laurence Fiette;Jaqueline Barra;Christian Muchardt

  • An injected bacterial effector targets chromatin access for transcription factor NF-kappaB to alter transcription of host genes involved in immune responses.

    Laurence Arbibe;Laurence Arbibe;Dong Wook Kim;Dong Wook Kim;Dong Wook Kim;Eric Batsche;Thierry Pedron;Thierry Pedron

  • Coordinated methyl and RNA binding is required for heterochromatin localization of mammalian HP1α

    Christian Muchardt;Marie Guillemé;Jacob‐S Seeler;Didier Trouche

  • RB and hbrm cooperate to repress the activation functions of E2F1

    Didier Trouche;Catherine Le Chalony;Christian Muchardt;Moshe Yaniv

  • Histone H3 lysine 9 trimethylation and HP1γ favor inclusion of alternative exons

    Violaine Saint-André;Violaine Saint-André;Violaine Saint-André;Eric Batsché;Eric Batsché;Eric Batsché;Christophe Rachez;Christophe Rachez;Christophe Rachez;Christian Muchardt;Christian Muchardt;Christian Muchardt

  • Argonaute proteins couple chromatin silencing to alternative splicing.

    Maya Ameyar-Zazoua;Christophe Rachez;Mouloud Souidi;Philippe Robin

  • Components of the Human SWI/SNF Complex Are Enriched in Active Chromatin and Are Associated with the Nuclear Matrix

    Jose C. Reyes;Christian Muchardt;Moshe Yaniv

  • The hbrm and BRG-1 proteins, components of the human SNF/SWI complex, are phosphorylated and excluded from the condensed chromosomes during mitosis.

    C. Muchardt;J. C. Reyes;B. Bourachot;E. Leguoy

  • When the SWI/SNF complex remodels...the cell cycle.

    Christian Muchardt;Moshe Yaniv

  • ATP-dependent chromatin remodelling: SWI/SNF and Co. are on the job.

    Christian Muchardt;Moshe Yaniv

  • SWI/SNF chromatin remodeling and cancer.

    Agnès Klochendler-Yeivin;Christian Muchardt;Moshe Yaniv

  • RB and c-Myc Activate Expression of the E-Cadherin Gene in Epithelial Cells through Interaction with Transcription Factor AP-2

    Eric Batsché;Christian Muchardt;Jürgen Behrens;Helen C. Hurst

  • A human protein with homology to Saccharomyces cerevisiae SNF5 interacts with the potential helicase hbrm

    Christian Muchardt;Claude Sardet;Brigitte Bourachot;Christina Onufryk

  • The reversible epigenetic silencing of BRM: implications for clinical targeted therapy

    S Glaros;G M Cirrincione;C Muchardt;C G Kleer

  • The translation elongation factor eEF1A1 couples transcription to translation during heat shock response

    Maria Vera;Bibhusita Pani;Lowri A Griffiths;Christian Muchardt

  • Tethering of HP1 proteins to chromatin is relieved by phosphoacetylation of histone H3

    Bogdan Mateescu;Patrick England;Frederic Halgand;Moshe Yaniv

Frequent Co-Authors

Moshe Yaniv
Moshe Yaniv Institut Pasteur
Pascale Cossart
Pascale Cossart Institut Pasteur
José C. Reyes
José C. Reyes Spanish National Research Council
Annick Harel-Bellan
Annick Harel-Bellan Centre national de la recherche scientifique, CNRS
Philippe J. Sansonetti
Philippe J. Sansonetti Institut Pasteur
Marie-Anne Nahori
Marie-Anne Nahori Institut Pasteur
Jan Willem Cohen Tervaert
Jan Willem Cohen Tervaert University of Alberta
Pier Luigi Meroni
Pier Luigi Meroni Istituto Auxologico Italiano
Dong-Wook Kim
Dong-Wook Kim Ewha Womans University
Daniel Henrion
Daniel Henrion University of Angers

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