Christian Muchardt mainly investigates SWI/SNF, Transcription factor, Molecular biology, Cell biology and Chromatin. He combines subjects such as RNA splicing, Spliceosome, Coding region, Exon and RNA polymerase II with his study of SWI/SNF. His studies in Transcription factor integrate themes in fields like Regulation of gene expression and Cancer research.
His Molecular biology research incorporates elements of Embryonic stem cell, Histone H3, EZH2 and Heterochromatin, Heterochromatin protein 1. His work carried out in the field of Cell biology brings together such families of science as Constitutive heterochromatin, Euchromatin, Non-histone protein, RNA-induced transcriptional silencing and Cell cycle. He studies Chromatin remodeling which is a part of Chromatin.
Christian Muchardt focuses on Cell biology, Chromatin, Molecular biology, Transcription factor and Genetics. His Cell biology research is multidisciplinary, incorporating perspectives in RNA, Transcription, Gene, Chromatin structure remodeling complex and RNA polymerase II. His work on Chromatin remodeling and SWI/SNF is typically connected to Context as part of general Chromatin study, connecting several disciplines of science.
His research on Molecular biology also deals with topics like
His main research concerns Cell biology, Gene, Chromatin, RNA and Alternative splicing. In general Cell biology, his work in Extracellular is often linked to Listeria monocytogenes linking many areas of study. In the subject of general Gene, his work in Heterochromatin is often linked to Cell type, thereby combining diverse domains of study.
Christian Muchardt interconnects Epigenetics, Neuroscience and DNA methylation in the investigation of issues within Chromatin. His DNA methylation study combines topics in areas such as Multiple sclerosis, Histone H3, Disease and Gene silencing. His Alternative splicing study integrates concerns from other disciplines, such as RNA polymerase II, Transcriptionally active chromatin and RNA splicing.
Christian Muchardt mainly focuses on Primary antiphospholipid syndrome, Antiphospholipid syndrome, Cell biology, MEDLINE and In patient. Christian Muchardt merges Cell biology with Endogenous retrovirus in his study. His studies deal with areas such as Anticoagulant, Additional Therapy, Pediatrics and Orphan drug as well as MEDLINE.
In patient is integrated with Genetic data, Bioinformatics, Some limitation, Identification and Systemic lupus in his research. Christian Muchardt undertakes multidisciplinary investigations into Genetic data and Systemic lupus erythematosus in his work. Christian Muchardt brings together Hydroxychloroquine and Secondary prevention to produce work in his papers.
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Purification and biochemical heterogeneity of the mammalian SWI-SNF complex.
Weidong Wang;Jacques Côté;Yutong Xue;Sharleen Zhou.
The EMBO Journal (1996)
A human homologue of Saccharomyces cerevisiae SNF2/SWI2 and Drosophila brm genes potentiates transcriptional activation by the glucocorticoid receptor.
C Muchardt;M Yaniv.
The EMBO Journal (1993)
The human SWI/SNF subunit Brm is a regulator of alternative splicing
Eric Batsché;Moshe Yaniv;Christian Muchardt.
Nature Structural & Molecular Biology (2006)
The murine SNF5/INI1 chromatin remodeling factor is essential for embryonic development and tumor suppression.
Agnes Klochendler‐Yeivin;Laurence Fiette;Jaqueline Barra;Christian Muchardt.
EMBO Reports (2000)
Altered control of cellular proliferation in the absence of mammalian brahma (SNF2α)
J. Reyes;J. Reyes;J. Barra;C. Muchardt;Anne Camus.
The EMBO Journal (1998)
An injected bacterial effector targets chromatin access for transcription factor NF-kappaB to alter transcription of host genes involved in immune responses.
Laurence Arbibe;Laurence Arbibe;Dong Wook Kim;Dong Wook Kim;Dong Wook Kim;Eric Batsche;Thierry Pedron;Thierry Pedron.
Nature Immunology (2007)
Coordinated methyl and RNA binding is required for heterochromatin localization of mammalian HP1α
Christian Muchardt;Marie Guillemé;Jacob‐S Seeler;Didier Trouche.
EMBO Reports (2002)
RB and hbrm cooperate to repress the activation functions of E2F1
Didier Trouche;Catherine Le Chalony;Christian Muchardt;Moshe Yaniv.
Proceedings of the National Academy of Sciences of the United States of America (1997)
Histone H3 lysine 9 trimethylation and HP1γ favor inclusion of alternative exons
Violaine Saint-André;Violaine Saint-André;Violaine Saint-André;Eric Batsché;Eric Batsché;Eric Batsché;Christophe Rachez;Christophe Rachez;Christophe Rachez;Christian Muchardt;Christian Muchardt;Christian Muchardt.
Nature Structural & Molecular Biology (2011)
Histone modifications induced by a family of bacterial toxins
Mélanie Anne Hamon;Eric Batsché;Béatrice Régnault;To Nam Tham.
Proceedings of the National Academy of Sciences of the United States of America (2007)
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