World's Best Scientists 2026 revealed!

D-Index & Metrics

Microbiology

D-Index
58
Citations
11906
World Ranking
3430
National Ranking
1354

Research.com Recognitions

  • 2018 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Bertram L. Jacobs is affiliated with Arizona State University in the United States. Their research spans several interconnected fields, focusing particularly on immunology, microbiology, and molecular biology. The main fields of study associated with their work include Immunology and Microbiology, Medicine, and Biochemistry, Genetics, and Molecular Biology.

The scientist's research interests cover a range of topics, with a strong emphasis on viral infections and immune responses. Notable topics they have contributed to are:

  • Poxvirus research and outbreaks
  • Interferon and immune responses
  • Cell death mechanisms and regulation
  • SARS-CoV-2 and COVID-19 research
  • Animal virus infections studies
  • Viral gastroenteritis research and epidemiology
  • Herpesvirus infections and treatments

Jacobs has published numerous scientific papers, including recent ones that have appeared in well-recognized journals. Examples of their recent work are:

  • Vaccinia virus E3 prevents sensing of Z-RNA to block ZBP1-dependent necroptosis, 2021, Cell Host & Microbe
  • Small Hero with Great Powers: Vaccinia Virus E3 Protein and Evasion of the Type I IFN Response, 2022, Biomedicines
  • Convergent Loss of the Necroptosis Pathway in Disparate Mammalian Lineages Shapes Viruses Countermeasures, 2021, Frontiers in Immunology
  • Canonical cellular stress granules are required for arsenite-induced necroptosis mediated by Z-DNA-binding protein 1, 2023, Science Signaling
  • Intranasal Immunization with a Vaccinia Virus Vaccine Vector Expressing Pre-Fusion Stabilized SARS-CoV-2 Spike Fully Protected Mice against Lethal Challenge with the Heavily Mutated Mouse-Adapted SARS2-N501YMA30 Strain of SARS-CoV-2, 2022, Vaccines

The venues where Bertram L. Jacobs frequently publishes include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cell Host & Microbe
  • Biomedicines
  • Frontiers in Immunology
  • Science Signaling

Among frequent collaborators, Jacobs has coauthored papers most often with:

  • Karen V. Kibler
  • Masmudur M. Rahman
  • Grant McFadden
  • Brenda G. Hogue
  • Mateusz Szczerba

Jacobs's subfields of study include Molecular Biology, Immunology, Infectious Diseases, Virology, and Epidemiology.

In recognition of their contributions to science, Bertram L. Jacobs was named a Fellow of the American Association for the Advancement of Science (AAAS) in 2018.

Best Publications

  • When two strands are better than one: The mediators and modulators of the cellular responses to double-stranded RNA

    Bertram L. Jacobs;Jeffrey O. Langland

  • The E3L gene of vaccinia virus encodes an inhibitor of the interferon-induced, double-stranded RNA-dependent protein kinase

    Hwai-Wen Chang;Julia C. Watson;Julia C. Watson;Bertram L. Jacobs

  • The E3L and K3L vaccinia virus gene products stimulate translation through inhibition of the double-stranded RNA-dependent protein kinase by different mechanisms.

    M. V. Davies;Hwai-Wen Chang;B. L. Jacobs;R. J. Kaufman

  • NS5A, a nonstructural protein of hepatitis C virus, binds growth factor receptor-bound protein 2 adaptor protein in a Src homology 3 domain/ligand-dependent manner and perturbs mitogenic signaling

    Seng-Lai Tan;Haruhisa Nakao;Yupeng He;Sangeetha Vijaysri

  • Vaccinia virus vaccines: past, present and future.

    Bertram L. Jacobs;Jeffrey O. Langland;Jeffrey O. Langland;Karen V. Kibler;Karen L. Denzler

  • Double-stranded RNA is a trigger for apoptosis in vaccinia virus-infected cells.

    Karen Kibler;Teri Shors;Kim B. Perkins;Cameron C. Zeman

  • Both Carboxy- and Amino-Terminal Domains of the Vaccinia Virus Interferon Resistance Gene, E3L, Are Required for Pathogenesis in a Mouse Model

    Teresa A. Brandt;Bertram L. Jacobs

  • Reversal of the interferon-sensitive phenotype of a vaccinia virus lacking E3L by expression of the reovirus S4 gene.

    Elizabeth Beattie;Karen L. Denzler;James Tartaglia;Marion E. Perkus

  • Isolation of a lethal virus from the endangered tiger salamander Ambystoma tigrinum stebbinsi

    James K. Jancovich;Elizabeth W. Davidson;J. Frank Morado;Bertram L. Jacobs

  • Inhibition of PKR by RNA and DNA viruses.

    Jeffrey O. Langland;Jason M. Cameron;Michael C. Heck;James K. Jancovich

  • TAR RNA-binding protein is an inhibitor of the interferon-induced protein kinase PKR

    Heesung Park;Monique V. Davies;Jeffrey O. Langland;Hwai-Wen Chang

  • A role for Z-DNA binding in vaccinia virus pathogenesis.

    Yang-Gyun Kim;Maneesha Muralinath;Teresa Brandt;Matthew Pearcy

  • Inhibitory activity for the interferon-induced protein kinase is associated with the reovirus serotype 1 sigma 3 protein.

    Farhad Imani;Bertram L. Jacobs

  • Blockade of Interferon Induction and Action by the E3L Double-Stranded RNA Binding Proteins of Vaccinia Virus

    Ying Xiang;Richard C Condit;Sangeetha Vijaysri;Bertram Jacobs

  • The Role of the PKR-Inhibitory Genes, E3L and K3L, in Determining Vaccinia Virus Host Range

    Jeffrey O. Langland;Bertram L. Jacobs

  • Identification of a Conserved Motif That Is Necessary for Binding of the Vaccinia Virus E3L Gene Products to Double-Stranded RNA

    Hwai-Wen Chang;Bertram L. Jacobs

  • Atomic force microscopy imaging of double stranded DNA and RNA.

    Yuri L. Lyubchenko;Alexander A. Gall;Lyuda S. Shlyakhtenko;Rodney E. Harrington

  • Subversion of Cell Signaling Pathways by Hepatitis C Virus Nonstructural 5A Protein via Interaction with Grb2 and P85 Phosphatidylinositol 3-Kinase

    Yupeng He;Haruhisa Nakao;Seng Lai Tan;Stephen J. Polyak

  • Evidence for emergence of an amphibian iridoviral disease because of human-enhanced spread.

    J. K. Jancovich;E. W. Davidson;N. Parameswaran;J. Mao

  • Evidence for Multiple Recent Host Species Shifts among the Ranaviruses (Family Iridoviridae)

    James K. Jancovich;Michel Bremont;Jeffrey W. Touchman;Bertram L. Jacobs

Frequent Co-Authors

Giuseppe Pantaleo
Giuseppe Pantaleo University of Lausanne
Mariano Esteban
Mariano Esteban Spanish National Research Council
Ralf Wagner
Ralf Wagner University of Regensburg
David C. Montefiori
David C. Montefiori Duke University
Georgia D. Tomaras
Georgia D. Tomaras Duke University
Guido Ferrari
Guido Ferrari Duke University
Mario Roederer
Mario Roederer National Institute of Allergy and Infectious Diseases
Jonathan L. Heeney
Jonathan L. Heeney University of Cambridge
James Tartaglia
James Tartaglia Sanofi (France)
Raphael Gottardo
Raphael Gottardo Fred Hutchinson Cancer Research Center

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

For students interested in Microbiology, exploring related online degrees offers flexible options to advance their education and career. Many aspiring healthcare professionals turn to the shortest online medical billing and coding certificate programs as a quick entry point into the healthcare field. These programs provide specialized skills that complement scientific knowledge with administrative expertise.

Alternatively, there are a variety of online healthcare degrees that cover broader aspects of medical science and patient care, including nursing, health informatics, and public health. These degrees often offer a perfect balance between theoretical knowledge and practical application.

For those interested in public health, the best easiest MPH online programs to get into provide accessible options to gain advanced expertise in epidemiology, biostatistics, and community health. Such programs align well with a microbiology background and open doors to leadership and research roles.

Students may also consider unique healthcare roles like becoming a child life specialist. This career combines healthcare and psychology to support pediatric patients emotionally and developmentally. Information about the child life specialist salary with bachelor degree highlights the potential for rewarding employment with a relevant undergraduate degree.

Exploring these related pathways can help microbiology students diversify their skills and enhance their career prospects in the growing healthcare field.

Best Scientists Citing Bertram L. Jacobs

Trending Scientists