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Biology and Biochemistry

D-Index
68
Citations
40845
World Ranking
7609
National Ranking
3460

Overview

Raphael Gottardo is affiliated with the Fred Hutchinson Cancer Research Center in the United States. Their research spans multiple disciplines within medicine, immunology, and molecular biology, with significant contributions in the fields of immunology, oncology, infectious diseases, and virology.

The scientist's primary areas of study include immunology and microbiology, medicine, and biochemistry, genetics, and molecular biology. Subfields with notable publication counts include immunology, molecular biology, oncology, infectious diseases, and virology. The main topics of their work focus on single-cell and spatial transcriptomics, CAR-T cell therapy research, immunotherapy and immune responses, immune cell function and interaction, T-cell and B-cell immunology, cancer immunotherapy and biomarkers, and HIV research and treatment.

Recent publications by Raphael Gottardo illustrate a focus on single-cell and spatial omics technologies, as well as immunological responses in disease contexts. Notable recent papers include:

  • Integrated analysis of multimodal single-cell data, 2021, Cell
  • Multiple early factors anticipate post-acute COVID-19 sequelae, 2022, Cell
  • Spatial transcriptomics at subspot resolution with BayesSpace, 2021, Nature Biotechnology
  • Multi-Omics Resolves a Sharp Disease-State Shift between Mild and Moderate COVID-19, 2020, Cell
  • Integrated analysis of multimodal single-cell data, 2020, bioRxiv (Cold Spring Harbor Laboratory)

Their collaborative network includes frequent coauthors such as Valentin Voillet, Philip D. Greenberg, Yapeng Su, Evan W. Newell, and Stanley R. Riddell. These collaborations have contributed to a range of publications across high-impact venues.

Raphael Gottardo's work has appeared predominantly in the following publication venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Cancer Research
  • The Journal of Immunology
  • Regular and Young Investigator Award Abstracts

Best Publications

  • Integrated analysis of multimodal single-cell data

    Yuhan Hao;Stephanie Hao;Erica Andersen-Nissen;William M. Mauck

  • Orchestrating high-throughput genomic analysis with Bioconductor

    Wolfgang Huber;Vincent J Carey;Robert Gentleman;Simon Anders

  • MAST: a flexible statistical framework for assessing transcriptional changes and characterizing heterogeneity in single-cell RNA sequencing data

    Greg Finak;Andrew McDavid;Masanao Yajima;Jingyuan Deng

  • Critical assessment of automated flow cytometry data analysis techniques

    Nima Aghaeepour;Greg Finak

  • Orchestrating Single-Cell Analysis with Bioconductor

    Robert A. Amezquita;Aaron T. L. Lun;Aaron T. L. Lun;Etienne Becht;Vince J. Carey

  • Multi-Omics Resolves a Sharp Disease-State Shift between Mild and Moderate COVID-19.

    Yapeng Su;Daniel Chen;Dan Yuan;Christopher Lausted

  • Spatial transcriptomics at subspot resolution with BayesSpace.

    Edward Zhao;Edward Zhao;Matthew R Stone;Xing Ren;Jamie Guenthoer

  • Exosomes in human semen carry a distinctive repertoire of small non-coding RNAs with potential regulatory functions

    Lucia Vojtech;Sangsoon Woo;Sean Hughes;Claire Levy

  • Safety and immunogenicity of a mRNA rabies vaccine in healthy adults: an open-label, non-randomised, prospective, first-in-human phase 1 clinical trial

    Martin Alberer;Ulrike Gnad-Vogt;Henoch Sangjoon Hong;Keyvan Tadjalli Mehr

  • Integrated analysis of multimodal single-cell data

    Yuhan Hao;Stephanie Hao;Erica Andersen-Nissen;William M. Mauck

  • Combining Mixture Components for Clustering

    Jean Patrick Baudry;Adrian E. Raftery;Gilles Celeux;Kenneth Lo

  • Data exploration, quality control and testing in single-cell qPCR-based gene expression experiments

    Andrew McDavid;Greg Finak;Pratip K. Chattopadyay;Maria Dominguez

  • Phosphoproteomic analysis of chimeric antigen receptor signaling reveals kinetic and quantitative differences that affect cell function.

    Alexander I. Salter;Richard G. Ivey;Jacob J. Kennedy;Valentin Voillet

  • Global Panel of HIV-1 Env Reference Strains for Standardized Assessments of Vaccine-Elicited Neutralizing Antibodies

    Allan deCamp;Peter Hraber;Robert T. Bailer;Michael S. Seaman

  • Automated gating of flow cytometry data via robust model-based clustering.

    Kenneth Lo;Ryan Remy Brinkman;Raphael Gottardo

  • Standardizing Flow Cytometry Immunophenotyping Analysis from the Human ImmunoPhenotyping Consortium

    Greg Finak;Marc Langweiler;Maria Jaimes;Mehrnoush Malek

  • COMPASS identifies T-cell subsets correlated with clinical outcomes

    Lin Lin;Greg Finak;Kevin Ushey;Chetan Seshadri

  • Acquired cancer resistance to combination immunotherapy from transcriptional loss of class I HLA

    K. G. Paulson;K. G. Paulson;K. G. Paulson;V. Voillet;M. S. McAfee;D. S. Hunter

  • T cell receptor gene therapy targeting WT1 prevents acute myeloid leukemia relapse post-transplant.

    Aude G. Chapuis;Aude G. Chapuis;Daniel N. Egan;Daniel N. Egan;Merav Bar;Merav Bar;Thomas M. Schmitt

  • Plasma IgG to Linear Epitopes in the V2 and V3 Regions of HIV-1 gp120 Correlate with a Reduced Risk of Infection in the RV144 Vaccine Efficacy Trial

    Raphael Gottardo;Robert T. Bailer;Bette T. Korber;S. Gnanakaran

Frequent Co-Authors

M. Juliana McElrath
M. Juliana McElrath University of Washington
Georgia D. Tomaras
Georgia D. Tomaras Duke University
David C. Montefiori
David C. Montefiori Duke University
Peter B. Gilbert
Peter B. Gilbert Fred Hutchinson Cancer Research Center
Giuseppe Pantaleo
Giuseppe Pantaleo University of Lausanne
Stephen C. De Rosa
Stephen C. De Rosa Fred Hutchinson Cancer Research Center
Richard H. Scheuermann
Richard H. Scheuermann J. Craig Venter Institute
Stanley R. Riddell
Stanley R. Riddell University of Washington
Mario Roederer
Mario Roederer National Institute of Allergy and Infectious Diseases
Guido Ferrari
Guido Ferrari Duke University

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