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Immunology

D-Index
55
Citations
11827
World Ranking
3798
National Ranking
143

Overview

Anja Roos is affiliated with Leiden University Medical Center in the Netherlands, focusing research efforts on several areas within medicine and immunology. Their work spans across immunology and microbiology, contributing specifically to the fields of immunodeficiency and autoimmune disorders, among other topics.

The scientist has contributed to research in main fields of study such as:

  • Medicine
  • Immunology and Microbiology

Subfields of study that feature prominently in their work include:

  • Immunology
  • Pulmonary and Respiratory Medicine
  • Genetics
  • Gastroenterology
  • Surgery

Key topics addressed in their publications cover:

  • Immunodeficiency and Autoimmune Disorders
  • Cystic Fibrosis Research Advances
  • Blood Disorders and Treatments
  • Celiac Disease Research and Management
  • Eosinophilic Esophagitis

Roos has published scientific articles in venues such as:

  • Frontiers in Immunology
  • Clinical & Translational Immunology

Significant recent papers include:

  • "Newborn Screening for Presymptomatic Diagnosis of Complement and Phagocyte Deficiencies" (2020) published in Frontiers in Immunology
  • "A novel method to standardise serum IgA measurements shows an increased prevalence of IgA deficiency in young children with recurrent respiratory tract infections" (2021) published in Clinical & Translational Immunology

Frequent coauthors working with Roos in various studies include:

  • Mahya Dezfouli
  • Sofia Bergström
  • Lillemor Skattum
  • Hassan Abolhassani
  • Maja Neiman

Best Publications

  • Structures of complement component C3 provide insights into the function and evolution of immunity

    Bert J. C. Janssen;Eric G. Huizinga;Hans C. A. Raaijmakers;Anja Roos

  • High‐Resolution Melting Analysis (HRMA)—More than just sequence variant screening

    Rolf H.A.M. Vossen;Emmelien Aten;Anja Roos;Johan T. den Dunnen

  • Immune evasion by a staphylococcal complement inhibitor that acts on C3 convertases.

    Suzan H M Rooijakkers;Maartje Ruyken;Anja Roos;Mohamed R Daha

  • Glomerular activation of the lectin pathway of complement in IgA nephropathy is associated with more severe renal disease.

    Anja Roos;Maria Pia Rastaldi;Novella Calvaresi;Beatrijs D. Oortwijn

  • Human IgA Activates the Complement System via the Mannan-Binding Lectin Pathway

    Roos A;Bouwman Lh;van Gijlswijk-Janssen Dj;Faber-Krol Mc

  • Biochemical and functional characterization of the interaction between pentraxin 3 and C1q.

    Alma J. Nauta;Barbara Bottazzi;Alberto Mantovani;Alberto Mantovani;Giovanni Salvatori

  • Mannose-binding lectin engagement with late apoptotic and necrotic cells.

    Alma J. Nauta;Nicoline Raaschou‐Jensen;Anja Roos;Mohamed R. Daha

  • Direct binding of C1q to apoptotic cells and cell blebs induces complement activation.

    Alma J. Nauta;Leendert A. Trouw;Mohamed R. Daha;Odette Tijsma

  • Secretory IgA N- and O-glycans provide a link between the innate and adaptive immune systems.

    Louise Royle;Anja Roos;David J. Harvey;Mark R. Wormald

  • Opsonization with C1q and Mannose-Binding Lectin Targets Apoptotic Cells to Dendritic Cells

    Alma J. Nauta;Giuseppe Castellano;Wei Xu;Andrea M. Woltman

  • Recognition and clearance of apoptotic cells: a role for complement and pentraxins.

    Alma J Nauta;Mohamed R Daha;Cees van Kooten;Anja Roos

  • Age and Sex-Associated Changes of Complement Activity and Complement Levels in a Healthy Caucasian Population

    Mariana Gaya de Costa;Felix Poppelaars;Felix Poppelaars;Cees van Kooten;Tom Eirik Mollnes;Tom Eirik Mollnes;Tom Eirik Mollnes

  • IL-10–producing macrophages preferentially clear early apoptotic cells

    Wei Xu;Anja Roos;Nicole Schlagwein;Andrea M. Woltman

  • Functional characterization of the lectin pathway of complement in human serum.

    Anja Roos;Lee H. Bouwman;Jeric Munoz;Tahlita Zuiverloon

  • MANNOSE-BINDING LECTIN: CLINICAL IMPLICATIONS FOR INFECTION, TRANSPLANTATION, AND AUTOIMMUNITY

    Lee H. Bouwman;Bart O. Roep;Anja Roos

  • Complement activation by (auto-) antibodies.

    Nina A. Daha;Nirmal K. Banda;Anja Roos;Frank J. Beurskens

  • Mini-review: A pivotal role for innate immunity in the clearance of apoptotic cells

    Anja Roos;Wei Xu;Giuseppe Castellano;Alma J Nauta

  • Maturation of dendritic cells abrogates C1q production in vivo and in vitro.

    Giuseppe Castellano;Andrea M. Woltman;Andrea M. Woltman;Alma J. Nauta;Alma J. Nauta;Anja Roos;Anja Roos

  • The membrane attack complex of complement induces caspase activation and apoptosis.

    Alma J. Nauta;Mohamed R. Daha;Odette Tijsma;Bob van de Water

  • Immunoglobulin M–Enriched Human Intravenous Immunoglobulin Prevents Complement Activation In Vitro and In Vivo in a Rat Model of Acute Inflammation

    Robert Rieben;Anja Roos;Anja Roos;Yvonne Muizert;Yvonne Muizert;Caroline Tinguely;Caroline Tinguely

  • Patients with igA nephropathy have increased serum galactose-deficient igA1 levels. Commentary

    A. Roos;C. Van Kooten;Z. Moldoveanu;R. J. Wyatt

Frequent Co-Authors

Mohamed R. Daha
Mohamed R. Daha Leiden University
Cees van Kooten
Cees van Kooten Leiden University Medical Center
Leendert A. Trouw
Leendert A. Trouw Leiden University Medical Center
Gregory L. Stahl
Gregory L. Stahl Brigham and Women's Hospital
Piet Gros
Piet Gros Utrecht University
Bart O. Roep
Bart O. Roep Leiden University Medical Center
Peter Garred
Peter Garred University of Copenhagen
Alberto Mantovani
Alberto Mantovani Humanitas University
Tom Eirik Mollnes
Tom Eirik Mollnes Oslo University Hospital
Teizo Fujita
Teizo Fujita Fukushima Prefectural General Hygiene Institute

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Related Online Degrees & Career Pathways

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