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Wolfgang Kastenmüller

Wolfgang Kastenmüller

D-Index & Metrics

Immunology

D-Index
50
Citations
14181
World Ranking
4196
National Ranking
276

Overview

Wolfgang Kastenmüller is affiliated with the University of Würzburg in Germany. Their research primarily focuses on the fields of Immunology and Microbiology, contributing to 60 publications in these areas. Within these domains, their work extends to subfields including Immunology, Molecular Biology, Oncology, Cancer Research, and Neurology.

The scientist's main research topics encompass:

  • Immune Cell Function and Interaction
  • T-cell and B-cell Immunology
  • Immunotherapy and Immune Responses
  • CAR-T cell therapy research
  • Immune cells in cancer
  • Cancer, Hypoxia, and Metabolism
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms

Wolfgang Kastenmüller has frequently published in several venues, including:

  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature (11 publications)
  • Nature Immunology (5 publications)
  • Immunity (4 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (4 publications)
  • Nature (2 publications)

The scientist has coauthored multiple studies with collaborators who have consistently contributed alongside them. Frequent coauthors include Konrad Knöpper, Martin Vaeth, Georg Gasteiger, Antoine-Emmanuel Saliba, and Milas Ugur.

Recent publications by Wolfgang Kastenmüller include the following:

  • CD4+ T cell-induced inflammatory cell death controls immune-evasive tumours, 2023, Nature
  • MYB orchestrates T cell exhaustion and response to checkpoint inhibition, 2022, Nature
  • The glucose transporter GLUT3 controls T helper 17 cell responses through glycolytic-epigenetic reprogramming, 2022, Cell Metabolism
  • Mitochondrial dysfunction promotes the transition of precursor to terminally exhausted T cells through HIF-1α-mediated glycolytic reprogramming, 2023, Nature Communications
  • Neutrophils self-limit swarming to contain bacterial growth in vivo, 2021, Science

Best Publications

  • CD4 + T cell help in cancer immunology and immunotherapy

    Jannie Borst;Tomasz Ahrends;Nikolina Bąbała;Cornelis J. M. Melief

  • Compartmentalized Control of Skin Immunity by Resident Commensals

    Shruti Naik;Nicolas Bouladoux;Christoph Wilhelm;Michael J. Molloy

  • Neutrophil swarms require LTB4 and integrins at sites of cell death in vivo

    Tim Lämmermann;Philippe V. Afonso;Bastian R. Angermann;Ji Ming Wang

  • The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation

    Bernardo S Franklin;Lukas Bossaller;Dominic De Nardo;Jacqueline M Ratter

  • Ultraviolet-radiation-induced inflammation promotes angiotropism and metastasis in melanoma

    Tobias Bald;Thomas Quast;Jennifer Landsberg;Meri Rogava

  • Microbiota-Derived Short-Chain Fatty Acids Promote the Memory Potential of Antigen-Activated CD8+ T Cells

    Annabell Bachem;Christina Makhlouf;Katrina J. Binger;David P. de Souza

  • Histo-Cytometry: A Method for Highly Multiplex Quantitative Tissue Imaging Analysis Applied to Dendritic Cell Subset Microanatomy in Lymph Nodes

    Michael Y. Gerner;Wolfgang Kastenmuller;Ina Ifrim;Juraj Kabat

  • A Spatially-Organized Multicellular Innate Immune Response in Lymph Nodes Limits Systemic Pathogen Spread

    Wolfgang Kastenmüller;Parizad Torabi-Parizi;Naeha Subramanian;Tim Lämmermann

  • Robust Anti-viral Immunity Requires Multiple Distinct T Cell-Dendritic Cell Interactions.

    Sarah Eickhoff;Anna Brewitz;Michael Y. Gerner;Frederick Klauschen

  • CD8+ T Cells Orchestrate pDC-XCR1+ Dendritic Cell Spatial and Functional Cooperativity to Optimize Priming.

    Anna Brewitz;Sarah Eickhoff;Sabrina Dähling;Thomas Quast

  • Functional classification of memory CD8(+) T cells by CX3CR1 expression.

    Jan P. Böttcher;Marc Beyer;Felix Meissner;Zeinab Abdullah

  • CD4+ T cell-induced inflammatory cell death controls immune-evasive tumours

    Unknown

  • Reactive Neutrophil Responses Dependent on the Receptor Tyrosine Kinase c-MET Limit Cancer Immunotherapy.

    Nicole Glodde;Nicole Glodde;Tobias Bald;Tobias Bald;Tobias Bald;Debby van den Boorn-Konijnenberg;Kyohei Nakamura

  • Crosstalk between Sentinel and Helper Macrophages Permits Neutrophil Migration into Infected Uroepithelium

    Marzena Schiwon;Christina Weisheit;Lars Franken;Sebastian Gutweiler

  • Tuning of Antigen Sensitivity by T Cell Receptor-Dependent Negative Feedback Controls T Cell Effector Function in Inflamed Tissues

    Tetsuya Honda;Jackson G. Egen;Tim Lämmermann;Wolfgang Kastenmüller

  • Dendritic cell-targeted vaccines — hope or hype?

    Wolfgang Kastenmüller;Kathrin Kastenmüller;Christian Kurts;Robert A. Seder

  • Peripheral prepositioning and local CXCL9 chemokine-mediated guidance orchestrate rapid memory CD8+ T cell responses in the lymph node.

    Wolfgang Kastenmüller;Marlene Brandes;Ze Wang;Jasmin Herz

  • Mitochondrial dysfunction promotes the transition of precursor to terminally exhausted T cells through HIF-1α-mediated glycolytic reprogramming

    Unknown

  • MYB orchestrates T cell exhaustion and response to checkpoint inhibition

    Unknown

  • Protective T cell immunity in mice following protein-TLR7/8 agonist-conjugate immunization requires aggregation, type I IFN, and multiple DC subsets.

    Kathrin Kastenmüller;Ulrike Wille-Reece;Ross W.B. Lindsay;Ross W.B. Lindsay;Lauren R. Trager

  • Identification of vaccinia virus epitope-specific HLA-A*0201-restricted T cells and comparative analysis of smallpox vaccines.

    Ingo Drexler;Caroline Staib;Wolfgang Kastenmüller;Stefan Stevanović

  • Spatiotemporal basis of innate and adaptive immunity in secondary lymphoid tissue

    Hai Qi;Wolfgang Kastenmüller;Ronald N. Germain

  • Dendritic cell and antigen dispersal landscapes regulate T cell immunity.

    Michael Y Gerner;Kerry A Casey;Wolfgang Kastenmuller;Ronald N Germain

Frequent Co-Authors

Ronald N. Germain
Ronald N. Germain National Institute of Allergy and Infectious Diseases
Christian Kurts
Christian Kurts University of Bonn
Natalio Garbi
Natalio Garbi University of Bonn
Percy A. Knolle
Percy A. Knolle Technical University of Munich
Eicke Latz
Eicke Latz German Rheumatism Research Centre
Gerd Sutter
Gerd Sutter Ludwig-Maximilians-Universität München
Dirk H. Busch
Dirk H. Busch Technical University of Munich
Jonel Trebicka
Jonel Trebicka University Hospital of Münster
Joachim L. Schultze
Joachim L. Schultze University of Bonn
Yasmine Belkaid
Yasmine Belkaid National Institute of Allergy and Infectious Diseases

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