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Thorsten R. Mempel

Thorsten R. Mempel

D-Index & Metrics

Immunology

D-Index
57
Citations
21038
World Ranking
3580
National Ranking
1658

Overview

Thorsten R. Mempel is affiliated with Harvard University in the United States. Their research primarily focuses on the fields of Immunology and Microbiology, with significant contributions to Medicine. Within these broader areas, their work spans subfields including Immunology, Oncology, Molecular Biology, Biomedical Engineering, and Pulmonary and Respiratory Medicine.

The scientist's main research topics encompass Immune Cell Function and Interaction, Immunotherapy and Immune Responses, Cancer Immunotherapy and Biomarkers, Immune cells in cancer, CAR-T cell therapy research, T-cell and B-cell Immunology, and Epigenetics and DNA Methylation.

They have published extensively in high-profile journals, with frequent contributions to the following venues:

  • Immunity
  • Cell
  • Regular and Young Investigator Award Abstracts
  • Annals of Oncology
  • bioRxiv (Cold Spring Harbor Laboratory)

Some of their recent papers include:

  • CXCL9:SPP1 macrophage polarity identifies a network of cellular programs that control human cancers (2023, Science)
  • CXCR6 positions cytotoxic T cells to receive critical survival signals in the tumor microenvironment (2021, Cell)
  • Dendritic cells as shepherds of T cell immunity in cancer (2023, Immunity)
  • Expansion of tumor-associated Treg cells upon disruption of a CTLA-4-dependent feedback loop (2021, Cell)
  • How chemokines organize the tumour microenvironment (2023, Nature reviews. Cancer)

Collaboration is a notable aspect of their work, with frequent co-authors including:

  • Mauro Di Pilato
  • Francesco Marangoni
  • Mikaël J. Pittet
  • Christopher Garris
  • Shivashankar Othy

Best Publications

  • Identification of splenic reservoir monocytes and their deployment to inflammatory sites

    Filip K. Swirski;Matthias Nahrendorf;Martin Etzrodt;Martin Etzrodt;Moritz Wildgruber

  • T-cell priming by dendritic cells in lymph nodes occurs in three distinct phases

    Thorsten R. Mempel;Sarah E. Henrickson;Ulrich H. von Andrian

  • Homing and cellular traffic in lymph nodes

    Ulrich H. von Andrian;Thorsten R. Mempel

  • Subcapsular sinus macrophages in lymph nodes clear lymph-borne viruses and present them to antiviral B cells

    Tobias Junt;E. Ashley Moseman;Matteo Iannacone;Steffen Massberg

  • The Transcription Factor NFAT Promotes Exhaustion of Activated CD8+ T Cells

    Gustavo J. Martinez;Renata M. Pereira;Tarmo Äijö;Tarmo Äijö;Edward Y. Kim

  • Orchestrating the orchestrators: chemokines in control of T cell traffic

    Shannon K Bromley;Thorsten R Mempel;Andrew D Luster

  • Regulatory T cells reversibly suppress cytotoxic T cell function independent of effector differentiation.

    Thorsten R. Mempel;Mikael J. Pittet;Khashayarsha Khazaie;Wolfgang Weninger

  • Visualization and tracking of tumour extracellular vesicle delivery and RNA translation using multiplexed reporters.

    Charles P. Lai;Edward Y. Kim;Christian E. Badr;Ralph Weissleder

  • Multidimensional communication in the microenvirons of glioblastoma.

    Marike L. Broekman;Marike L. Broekman;Sybren L. N. Maas;Sybren L. N. Maas;Erik R. Abels;Thorsten R. Mempel

  • Conduits Mediate Transport of Low-Molecular-Weight Antigen to Lymph Node Follicles

    Ramon Roozendaal;Thorsten R. Mempel;Lisa A. Pitcher;Santiago F. Gonzalez

  • T cell sensing of antigen dose governs interactive behavior with dendritic cells and sets a threshold for T cell activation

    Sarah E Henrickson;Thorsten R Mempel;Irina B Mazo;Bai Liu

  • CXCR3 chemokine receptor-ligand interactions in the lymph node optimize CD4+ T helper 1 cell differentiation.

    Joanna R. Groom;Jillian Richmond;Thomas T. Murooka;Elizabeth W. Sorensen

  • CXCR6 positions cytotoxic T cells to receive critical survival signals in the tumor microenvironment.

    Mauro Di Pilato;Mauro Di Pilato;Raphael Kfuri-Rubens;Raphael Kfuri-Rubens;Jasper N. Pruessmann;Aleksandra J. Ozga

  • CCR7 ligands stimulate the intranodal motility of T lymphocytes in vivo.

    Tim Worbs;Thorsten R. Mempel;Jasmin Bölter;Ulrich H. von Andrian

  • Definition of Germinal-Center B Cell Migration In Vivo Reveals Predominant Intrazonal Circulation Patterns

    Anja E. Hauser;Tobias Junt;Thorsten R. Mempel;Michael W. Sneddon

  • Intravital Microscopy: Visualizing Immunity in Context

    Cenk Sumen;Thorsten R. Mempel;Irina B. Mazo;Ulrich H. von Andrian

  • HIV-infected T cells are migratory vehicles for viral dissemination

    Thomas Murooka;Maud Deruaz;Francesco Marangoni;Vladimir D. Vrbanac

  • SCS macrophages suppress melanoma by restricting tumor-derived vesicle-B cell interactions.

    Ferdinando Pucci;Christopher Garris;Charles P. Lai;Andita Newton

  • Dynamic Treg interactions with intratumoral APCs promote local CTL dysfunction

    Christian A. Bauer;Edward Y. Kim;Francesco Marangoni;Esteban Carrizosa

  • Dendritic cells as shepherds of T cell immunity in cancer

    Unknown

  • In vivo imaging of leukocyte trafficking in blood vessels and tissues.

    Thorsten R Mempel;M Lucila Scimone;J Rodrigo Mora;Ulrich H von Andrian

  • The Transcription Factor NFAT Exhibits Signal Memory during Serial T Cell Interactions with Antigen-Presenting Cells

    Francesco Marangoni;Thomas T. Murooka;Teresa Manzo;Edward Y. Kim

Frequent Co-Authors

Ulrich H. von Andrian
Ulrich H. von Andrian Harvard University
Andrew D. Luster
Andrew D. Luster Harvard University
Sarah E. Henrickson
Sarah E. Henrickson Raymond and Ruth Perelman School of Medicine at the University of Pennsylvania
Mikael J. Pittet
Mikael J. Pittet University of Geneva
Tobias Junt
Tobias Junt Novartis (Switzerland)
Ralph Weissleder
Ralph Weissleder Harvard University
Roberto Bonasio
Roberto Bonasio University of Pennsylvania
Xandra O. Breakefield
Xandra O. Breakefield Harvard University
Michael C. Carroll
Michael C. Carroll Boston Children's Hospital
Richard L. Proia
Richard L. Proia National Institutes of Health

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