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Sheila M. Keating

Sheila M. Keating

University of California, San Francisco
United States

Overview

What is she best known for?

The fields of study she is best known for:

  • Internal medicine
  • Immune system
  • Virus

Sheila M. Keating spends much of her time researching Immunology, Virology, T cell, Vaccination and Plasmodium falciparum. Her Immunology research incorporates themes from Vaccinia and Hematopoietic stem cell transplantation. The concepts of her Hematopoietic stem cell transplantation study are interwoven with issues in Lymph node and Blood plasma.

In her study, Circumsporozoite protein is strongly linked to Immunogenicity, which falls under the umbrella field of Virology. Her Virus research is multidisciplinary, relying on both Innate immune system and Immune system. As a part of the same scientific family, she mostly works in the field of Stem cell, focusing on Peripheral and, on occasion, Viral load.

Her most cited work include:

  • Recombinant modified vaccinia virus Ankara expressing antigen 85A boosts BCG-primed and naturally acquired antimycobacterial immunity in humans. (528 citations)
  • Antiretroviral-Free HIV-1 Remission and Viral Rebound After Allogeneic Stem Cell Transplantation: Report of 2 Cases (303 citations)
  • Long-Term Reduction in Peripheral Blood HIV Type 1 Reservoirs Following Reduced-Intensity Conditioning Allogeneic Stem Cell Transplantation (237 citations)

What are the main themes of her work throughout her whole career to date?

Her scientific interests lie mostly in Immunology, Virology, Internal medicine, Viral load and Immune system. Inflammation, Vaccination, Cytokine, T cell and Chemokine are subfields of Immunology in which her conducts study. Her study of Virus is a part of Virology.

Her biological study spans a wide range of topics, including Gastroenterology, Endocrinology, Oncology and Cardiology. Her work deals with themes such as Stem cell, Hiv incidence and Transplantation, which intersect with Viral load. Her research in Antibody intersects with topics in HIV Antigens and Antigen.

She most often published in these fields:

  • Immunology (68.09%)
  • Virology (49.47%)
  • Internal medicine (23.94%)

What were the highlights of her more recent work (between 2018-2021)?

  • Internal medicine (23.94%)
  • Immune system (20.74%)
  • Immunology (68.09%)

In recent papers she was focusing on the following fields of study:

Her primary scientific interests are in Internal medicine, Immune system, Immunology, T cell and Avidity. Her studies deal with areas such as Antibody, Critically ill, Physiology and Transplantation as well as Immune system. Her Antibody study integrates concerns from other disciplines, such as Clinical trial, Cohort and Virology.

Her Virology research incorporates elements of Clinical microbiology and Antiretroviral therapy. Her Immunology research integrates issues from Effects of sleep deprivation on cognitive performance and Serum albumin. Sheila M. Keating interconnects Incidence and Viral load in the investigation of issues within Avidity.

Between 2018 and 2021, her most popular works were:

  • Intradonor reproducibility and changes in hemolytic variables during red blood cell storage: results of recall phase of the REDS-III RBC-Omics study (25 citations)
  • Piloting and implementation of quality assessment and quality control procedures in RBC-Omics: a large multi-center study of red blood cell hemolysis during storage. (14 citations)
  • Assessing intra-lab precision and inter-lab repeatability of outgrowth assays of HIV-1 latent reservoir size. (11 citations)

In her most recent research, the most cited papers focused on:

  • Internal medicine
  • Immune system
  • Virus

Gold standard, Statistics, Repeatability, Biomedical engineering and Confidence interval are her primary areas of study. Her work carried out in the field of Statistics brings together such families of science as Incidence, Viral load and Antigen. Her Antigen study typically links adjacent topics like Reproducibility.

Her Reproducibility research includes themes of Concordance, Red blood cell and Avidity. Her Repeatability study combines topics in areas such as Reliability, Percentage point and Accuracy and precision.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Recombinant modified vaccinia virus Ankara expressing antigen 85A boosts BCG-primed and naturally acquired antimycobacterial immunity in humans.

Helen McShane;Ansar A Pathan;Clare R Sander;Sheila M Keating.
Nature Medicine (2004)

753 Citations

Antiretroviral-Free HIV-1 Remission and Viral Rebound After Allogeneic Stem Cell Transplantation: Report of 2 Cases

Timothy J. Henrich;Emily Hanhauser;Francisco M. Marty;Michael N. Sirignano.
Annals of Internal Medicine (2014)

435 Citations

Enhanced T cell-mediated protection against malaria in human challenges by using the recombinant poxviruses FP9 and modified vaccinia virus Ankara

Daniel P. Webster;Susanna Dunachie;Jenni M. Vuola;Tamara Berthoud.
Proceedings of the National Academy of Sciences of the United States of America (2005)

325 Citations

Long-Term Reduction in Peripheral Blood HIV Type 1 Reservoirs Following Reduced-Intensity Conditioning Allogeneic Stem Cell Transplantation

Timothy J. Henrich;Timothy J. Henrich;Zixin Hu;Zixin Hu;Jonathan Z. Li;Jonathan Z. Li;Gaia Sciaranghella.
The Journal of Infectious Diseases (2013)

320 Citations

Challenges in Detecting HIV Persistence during Potentially Curative Interventions: A Study of the Berlin Patient

Steven A. Yukl;Eli Boritz;Michael Busch;Christopher Bentsen.
PLOS Pathogens (2013)

301 Citations

A DNA prime-modified vaccinia virus ankara boost vaccine encoding thrombospondin-related adhesion protein but not circumsporozoite protein partially protects healthy malaria-naive adults against Plasmodium falciparum sporozoite challenge.

S. J. Dunachie;M. Walther;J. E. Epstein;S. Keating.
Infection and Immunity (2006)

233 Citations

A randomised, double-blind, controlled vaccine efficacy trial of DNA/MVA ME-TRAP against malaria infection in Gambian adults.

Vasee S Moorthy;Egeruan B Imoukhuede;Paul Milligan;Kalifa Bojang.
PLOS Medicine (2004)

211 Citations

Immune and Genetic Correlates of Vaccine Protection Against Mucosal Infection by SIV in Monkeys

Norman L. Letvin;Srinivas S. Rao;David C. Montefiori;Michael S. Seaman.
Science Translational Medicine (2011)

207 Citations

Differential Immunogenicity of Various Heterologous Prime-Boost Vaccine Regimens Using DNA and Viral Vectors in Healthy Volunteers

Jenni M. Vuola;Sheila Keating;Daniel P. Webster;Tamara Berthoud.
Journal of Immunology (2005)

185 Citations

Durable Human Memory T Cells Quantifiable by Cultured Enzyme-Linked Immunospot Assays Are Induced by Heterologous Prime Boost Immunization and Correlate with Protection against Malaria

Sheila M. Keating;Philip Bejon;Tamara Berthoud;Jenni M. Vuola.
Journal of Immunology (2005)

174 Citations

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