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Biology and Biochemistry

D-Index
79
Citations
23601
World Ranking
4285
National Ranking
323

Overview

Paul A. Kroon is affiliated with Norwich Research Park in the United Kingdom. Their research focuses on areas within medicine and biochemistry, genetics, and molecular biology, with an emphasis on molecular biology, physiology, and biochemistry. The research spans several topics including gut microbiota and health, nutritional studies and diet, phytochemicals and antioxidant activities, diet and metabolism studies, tea polyphenols and effects, dietary effects on health, and nutrition and health in aging.

Frequent publication venues for Paul A. Kroon include:

  • Molecular Nutrition & Food Research
  • Nutrients
  • Journal of Nutrition
  • Proceedings of The Nutrition Society
  • Clinical Nutrition

Recent papers authored or co-authored by Paul A. Kroon include:

  • A polyphenol-rich dietary pattern improves intestinal permeability, evaluated as serum zonulin levels, in older subjects: The MaPLE randomised controlled trial (2020), Clinical Nutrition
  • Inhibitory Effects of Quercetin and Its Main Methyl, Sulfate, and Glucuronic Acid Conjugates on Cytochrome P450 Enzymes, and on OATP, BCRP and MRP2 Transporters (2020), Nutrients
  • Crosstalk among intestinal barrier, gut microbiota and serum metabolome after a polyphenol-rich diet in older subjects with "leaky gut": The MaPLE trial (2021), Clinical Nutrition
  • The use of an in-vitro batch fermentation (human colon) model for investigating mechanisms of TMA production from choline, l-carnitine and related precursors by the human gut microbiota (2021), European Journal of Nutrition
  • Effect of a polyphenol-rich dietary pattern on intestinal permeability and gut and blood microbiomics in older subjects: study protocol of the MaPLE randomised controlled trial (2020), BMC Geriatrics

Paul A. Kroon has collaborated extensively with several co-authors, including:

  • Cristina Andrés-Lacueva
  • Cristian Del Bo'
  • Antonio Cherubini
  • Giorgio Gargari
  • Simone Guglielmetti

The scholarly work of Paul A. Kroon is situated primarily in investigating how dietary components-especially polyphenols-interact with intestinal permeability, gut microbiota, and metabolism, with a particular consideration on the effects in older populations. This research covers both mechanistic studies and randomized controlled trials that explore the molecular and physiological impacts of dietary patterns on health.

Best Publications

  • Flavonoids, flavonoid-rich foods, and cardiovascular risk: a meta-analysis of randomized controlled trials

    Lee Hooper;Paul A Kroon;Eric B Rimm;Jeffrey S Cohn

  • Dietary flavonoid and isoflavone glycosides are hydrolysed by the lactase site of lactase phlorizin hydrolase

    Andrea J Day;F.Javier Cañada;Juan C Dı́az;Paul A Kroon

  • Deglycosylation by small intestinal epithelial cell beta-glucosidases is a critical step in the absorption and metabolism of dietary flavonoid glycosides in humans.

    Kitti Németh;Geoff W. Plumb;Jean Guy Berrin;Nathalie Juge

  • Effects of chocolate, cocoa, and flavan-3-ols on cardiovascular health: a systematic review and meta-analysis of randomized trials

    Lee Hooper;Colin D. Kay;Asmaa Abdelhamid;Paul A. Kroon

  • How should we assess the effects of exposure to dietary polyphenols in vitro

    Paul A Kroon;Michael N Clifford;Alan Crozier;Andrea J Day

  • Profiling glucosinolates and phenolics in vegetative and reproductive tissues of the multi-purpose trees Moringa oleifera L. (horseradish tree) and Moringa stenopetala L.

    Richard N Bennett;Fred A Mellon;Nikolaus Foidl;John H Pratt

  • Globe artichoke: A functional food and source of nutraceutical ingredients

    Vincenzo Lattanzio;Paul A. Kroon;Vito Linsalata;Angela Cardinali

  • Human metabolism and elimination of the anthocyanin, cyanidin-3-glucoside: a 13C-tracer study

    Charles Czank;Aedín Cassidy;Qingzhi Zhang;Douglas J Morrison

  • The pharmacokinetics of anthocyanins and their metabolites in humans

    R M de Ferrars;C Czank;Q Zhang;N P Botting

  • Hydroxycinnamates in plants and food: current and future perspectives†

    Paul A Kroon;Gary Williamson

  • Esterase activity able to hydrolyze dietary antioxidant hydroxycinnamates is distributed along the intestine of mammals.

    Mette F. Andreasen;Paul A. Kroon;Gary Williamson;Maria-Teresa Garcia-Conesa

  • Intestinal release and uptake of phenolic antioxidant diferulic acids.

    Mette F. Andreasen;Paul A. Kroon;Gary Williamson;Maria Teresa Garcia-Conesa

  • Release of covalently bound ferulic acid from fiber in the human colon

    Paul A. Kroon;Craig B. Faulds;Peter Ryden;James A. Robertson

  • Systematic Review on Polyphenol Intake and Health Outcomes: Is there Sufficient Evidence to Define a Health-Promoting Polyphenol-Rich Dietary Pattern?

    Cristian Del Bo;Stefano Bernardi;Mirko Marino;Marisa Porrini

  • Absorption/metabolism of sulforaphane and quercetin, and regulation of phase II enzymes, in human jejunum in vivo.

    Niclas Petri;Christer Tannergren;Birgit Holst;Birgit Holst;Fred A. Mellon

  • Plant Phenolics – Secondary Metabolites with Diverse Functions

    Vincenzo Lattanzio;Paul A. Kroon;Stéphane Quideau;Dieter Treutter

  • Hairy plant polysaccharides: a close shave with microbial esterases

    Gary Williamson;Paul A. Kroon;CRaig B. Faulds

  • High contents of nonextractable polyphenols in fruits suggest that polyphenol contents of plant foods have been underestimated.

    Sara Arranz;Fulgencio Saura-Calixto;Shika Shaha;Paul A. Kroon

  • The faeA genes from Aspergillus niger and Aspergillus tubingensis encode ferulic acid esterases involved in degradation of complex cell wall polysaccharides.

    R.P. de Vries;B. Michelsen;C.H. Poulsen;P.A. Kroon

  • Absorption of hydroxycinnamates in humans after high-bran cereal consumption.

    Sandra M Kern;Richard N Bennett;Fred A Mellon;Paul Anthony Kroon

Frequent Co-Authors

Gary Williamson
Gary Williamson Monash University
Cristina Andres-Lacueva
Cristina Andres-Lacueva University of Barcelona
Craig B. Faulds
Craig B. Faulds Aix-Marseille University
Aedin Cassidy
Aedin Cassidy Queen's University Belfast
Nathalie Juge
Nathalie Juge Norwich Research Park
Antonio Cherubini
Antonio Cherubini University of Perugia
Patrizia Riso
Patrizia Riso University of Milan
Simone Guglielmetti
Simone Guglielmetti University of Milano-Bicocca
Francisco A. Tomás-Barberán
Francisco A. Tomás-Barberán Spanish National Research Council
Marisa Porrini
Marisa Porrini University of Milan

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