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D-Index & Metrics

Genetics

D-Index
65
Citations
19829
World Ranking
2673
National Ranking
340

Overview

Susan M. Farrington is affiliated with the University of Edinburgh in the United Kingdom and has a substantial research profile centered on Medicine, with considerable contributions to Biochemistry, Genetics, and Molecular Biology. Their work covers various subfields including Pathology and Forensic Medicine, Genetics, Molecular Biology, Oncology, and Cancer Research.

Their main research topics encompass genetic factors in colorectal cancer, genetic associations and epidemiology, cancer-related molecular mechanisms, vitamin D research studies, colorectal cancer screening and detection, epigenetics and DNA methylation, and nutrition, genetics, and disease.

Farrington has published extensively in venues such as the British Journal of Cancer, bioRxiv (Cold Spring Harbor Laboratory), International Journal of Cancer, Annals of the Rheumatic Diseases, and Nature Communications.

Frequent co-authors of Farrington include Malcolm G. Dunlop, Maria Timofeeva, Evropi Theodoratou, P G Vaughan-Shaw, and Xue Li.

Notable recent publications include:

  • Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries, 2022, Nature Genetics
  • Identification of novel protein biomarkers and drug targets for colorectal cancer by integrating human plasma proteome with genome, 2023, Genome Medicine
  • Glycosylation of immunoglobulin G is regulated by a large network of genes pleiotropic with inflammatory diseases, 2020, Science Advances
  • The effect of vitamin D supplementation on survival in patients with colorectal cancer: systematic review and meta-analysis of randomised controlled trials, 2020, British Journal of Cancer
  • Genetically predicted physical activity levels are associated with lower colorectal cancer risk: a Mendelian randomisation study, 2021, British Journal of Cancer

Best Publications

  • Runs of Homozygosity in European Populations

    Ruth McQuillan;Anne-Louise Leutenegger;Rehab Abdel-Rahman;Rehab Abdel-Rahman;Christopher S. Franklin

  • Modulation of genetic associations with serum urate levels by body-mass-index in humans

    Jennifer E. Huffman;Eva Albrecht;Alexander Teumer;Massimo Mangino

  • Genome-wide association analyses identify 18 new loci associated with serum urate concentrations

    Anna Köttgen;Anna Köttgen;Eva Albrecht;Alexander Teumer;Veronique Vitart

  • Genome-wide association scan identifies a colorectal cancer susceptibility locus on chromosome 8q24

    Brent W. Zanke;Celia M.T. Greenwood;Celia M.T. Greenwood;Jagadish Rangrej;Rafal Kustra;Rafal Kustra

  • Cancer Risk Associated with Germline DNA Mismatch Repair Gene Mutations

    Malcolm G. Dunlop;Susan M. Farrington;Susan M. Farrington;Andrew D. Carothers;Andrew H. Wyllie

  • Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21.

    Albert Tenesa;Susan M Farrington;James G D Prendergast;Mary E Porteous

  • A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3

    Ian P.M. Tomlinson;Emily Webb;Luis Carvajal-Carmona;Peter Broderick

  • Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer

    Richard S. Houlston;Emily Webb;Peter Broderick;Alan M. Pittman

  • Identification and Survival of Carriers of Mutations in DNA Mismatch-Repair Genes in Colon Cancer

    Rebecca A Barnetson;Albert Tenesa;Susan M Farrington;Iain D Nicholl

  • Application of a 5-tiered scheme for standardized classification of 2,360 unique mismatch repair gene variants in the InSiGHT locus-specific database

    Bryony A Thompson;Bryony A Thompson;Amanda B Spurdle;John-Paul Plazzer;Marc S Greenblatt

  • Genetic instability occurs in the majority of young patients with colorectal cancer

    Bo Liu;Susan M. Farrington;Gloria M. Petersen;Stanley R. Hamilton

  • Risks of Lynch Syndrome Cancers for MSH6 Mutation Carriers

    Laura Baglietto;Noralane M. Lindor;James G. Dowty;Darren M. White

  • Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33

    Richard S Houlston;Jeremy Peter Cheadle;Sara E. Dobbins;Albert Tenesa

  • APC mutations in colorectal tumors with mismatch repair deficiency

    Jian Huang;Nickolas Papadopoulos;Aileen J. McKinley;Susan M. Farrington

  • Germline Susceptibility to Colorectal Cancer Due to Base-Excision Repair Gene Defects

    Susan M. Farrington;Albert Tenesa;Rebecca Barnetson;Alice Wiltshire

  • Genome-wide Association Study in 79,366 European-ancestry Individuals Informs the Genetic Architecture of 25-Hydroxyvitamin D Levels

    Xia Jiang;Xia Jiang;Paul F. O'Reilly;Hugues Aschard;Hugues Aschard;Yi Hsiang Hsu;Yi Hsiang Hsu

  • Common genetic variants at the CRAC1 (HMPS) locus on chromosome 15q13.3 influence colorectal cancer risk

    Emma Jaeger;Emily Webb;Kimberley Howarth;Luis Carvajal-Carmona

  • Meta-analysis identifies multiple loci associated with kidney function–related traits in east Asian populations

    Y. Okada;X. Sim;X. Sim;M. J. Go;J. Y. Wu;J. Y. Wu

  • WWOX: A candidate tumor suppressor gene involved in multiple tumor types

    A. J. W. Paige;K. J. Taylor;C. Taylor;S. G. Hillier

  • Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk

    Malcolm G Dunlop;Sara E Dobbins;Susan Mary Farrington;Angela M Jones

Frequent Co-Authors

Malcolm G. Dunlop
Malcolm G. Dunlop University of Edinburgh
Harry Campbell
Harry Campbell University of Edinburgh
Albert Tenesa
Albert Tenesa University of Edinburgh
Evropi Theodoratou
Evropi Theodoratou University of Edinburgh
Lina Zgaga
Lina Zgaga Trinity College Dublin
Ian Tomlinson
Ian Tomlinson University of Oxford
Richard S. Houlston
Richard S. Houlston Institute of Cancer Research
Peter Broderick
Peter Broderick Institute of Cancer Research
David J. Kerr
David J. Kerr University of Oxford
Igor Rudan
Igor Rudan University of Edinburgh

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