Mira Rosenblat

Overview

Best Publications

• Paraoxonase inhibits high-density lipoprotein oxidation and preserves its functions. A possible peroxidative role for paraoxonase.

  M Aviram;M Rosenblat;C L Bisgaier;R S Newton

  1601
  Citations

• Pomegranate juice consumption reduces oxidative stress, atherogenic modifications to LDL, and platelet aggregation: studies in humans and in atherosclerotic apolipoprotein E–deficient mice

  Michael Aviram;Leslie Dornfeld;Mira Rosenblat;Nina Volkova

  1178
  Citations

• Human serum paraoxonase (PON 1) is inactivated by oxidized low density lipoprotein and preserved by antioxidants.

  Michael Aviram;Mira Rosenblat;Scott Billecke;John Erogul

  875
  Citations

• Reduced Progression of Atherosclerosis in Apolipoprotein E–Deficient Mice Following Consumption of Red Wine, or Its Polyphenols Quercetin or Catechin, Is Associated With Reduced Susceptibility of LDL to Oxidation and Aggregation

  Tony Hayek;Bianca Fuhrman;Jacob Vaya;Mira Rosenblat

  811
  Citations

• Human Serum Paraoxonases (PON1) Q and R Selectively Decrease Lipid Peroxides in Human Coronary and Carotid Atherosclerotic Lesions PON1 Esterase and Peroxidase-Like Activities

  Michael Aviram;Emiliya Hardak;Jacob Vaya;Saeed Mahmood

  664
  Citations

• Paraoxonase Active Site Required for Protection Against LDL Oxidation Involves Its Free Sulfhydryl Group and Is Different From That Required for Its Arylesterase/Paraoxonase Activities Selective Action of Human Paraoxonase Allozymes Q and R

  Michael Aviram;Scott Billecke;Robert Sorenson;Charles Bisgaier

  651
  Citations

• Paraoxonases 1, 2, and 3, oxidative stress, and macrophage foam cell formation during atherosclerosis development.

  Michael Aviram;Mira Rosenblat

  607
  Citations

• Ginger Extract Consumption Reduces Plasma Cholesterol, Inhibits LDL Oxidation and Attenuates Development of Atherosclerosis in Atherosclerotic, Apolipoprotein E-Deficient Mice

  Bianca Fuhrman;Mira Rosenblat;Tony Hayek;Raymond Coleman

  533
  Citations

• Atorvastatin and gemfibrozil metabolites, but not the parent drugs, are potent antioxidants against lipoprotein oxidation

  Michael Aviram;Mira Rosenblat;Charles L Bisgaier;Roger S Newton

  464
  Citations

• Paraoxonase (PON1) deficiency is associated with increased macrophage oxidative stress: studies in PON1-knockout mice

  Orit Rozenberg;Mira Rosenblat;Raymond Coleman;Diana M Shih

  399
  Citations

• Pomegranate juice flavonoids inhibit low-density lipoprotein oxidation and cardiovascular diseases: studies in atherosclerotic mice and in humans

  M Aviram;L Dornfeld;M Kaplan;R Coleman

  392
  Citations

• Pomegranate phenolics from the peels, arils, and flowers are antiatherogenic: studies in vivo in atherosclerotic apolipoprotein e-deficient (E 0) mice and in vitro in cultured macrophages and lipoproteins.

  Michael Aviram;Nina Volkova;Raymond Coleman;Mark Dreher

  356
  Citations

• The catalytic histidine dyad of high density lipoprotein-associated serum paraoxonase-1 (PON1) is essential for PON1-mediated inhibition of low density lipoprotein oxidation and stimulation of macrophage cholesterol efflux.

  Mira Rosenblat;Leonid Gaidukov;Olga Khersonsky;Jacob Vaya

  326
  Citations

• Lycopene Synergistically Inhibits LDL Oxidation in Combination with Vitamin E, Glabridin, Rosmarinic Acid, Carnosic Acid, or Garlic

  Bianca Fuhrman;Nina Volkova;Mira Rosenblat;Michael Aviram

  311
  Citations

• Paraoxonase 1 (PON1) enhances HDL-mediated macrophage cholesterol efflux via the ABCA1 transporter in association with increased HDL binding to the cells: a possible role for lysophosphatidylcholine.

  Mira Rosenblat;Jacob Vaya;Diana Shih;Michael Aviram

  271
  Citations

• The antioxidative effects of the isoflavan glabridin on endogenous constituents of LDL during its oxidation

  Paula A. Belinky;Michael Aviram;Bianca Fuhrman;Mira Rosenblat

  224
  Citations

• The licorice root derived isoflavan glabridin inhibits the activities of human cytochrome P450S 3A4, 2B6, and 2C9.

  Ute M. Kent;Michael Aviram;Mira Rosenblat;Paul F. Hollenberg

  199
  Citations

• Paraoxonases and cardiovascular diseases: pharmacological and nutritional influences.

  Michael Aviram;Mira Rosenblat

  183
  Citations

• The 192R/Q polymorphs of serum paraoxonase PON1 differ in HDL binding, lipolactonase stimulation, and cholesterol efflux

  Leonid Gaidukov;Mira Rosenblat;Michael Aviram;Dan S. Tawfik

  182
  Citations

• Macrophage glutathione content and glutathione peroxidase activity are inversely related to cell-mediated oxidation of LDL: in vitro and in vivo studies.

  Mira Rosenblat;Michael Aviram

  182
  Citations