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Jean-Pierre Julien

Jean-Pierre Julien

D-Index & Metrics

Medicine

D-Index
83
Citations
26230
World Ranking
15572
National Ranking
648

Overview

Jean-Pierre Julien is affiliated with Université Laval in Canada and has contributed extensively to the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their research primarily focuses on Neurology, Genetics, Cell Biology, Molecular Biology, and Cellular and Molecular Neuroscience.

The scientist's work covers a range of topics including Amyotrophic Lateral Sclerosis Research, Neurogenetic and Muscular Disorders Research, Parkinson's Disease Mechanisms and Treatments, Skin and Cellular Biology Research, Genetic Neurodegenerative Diseases, Biochemical Acid Research Studies, and Cancer-related gene regulation.

Jean-Pierre Julien's recent publications reflect a focus on neurodegenerative diseases and molecular mechanisms. Notable papers include:

  • Induction of autophagy mitigates TDP-43 pathology and translational repression of neurofilament mRNAs in mouse models of ALS/FTD, 2021, Molecular Neurodegeneration
  • Mitigation of ALS Pathology by Neuron-Specific Inhibition of Nuclear Factor Kappa B Signaling, 2020, Journal of Neuroscience
  • Modeling of Electronic Mobilities in Halide Perovskites: Adiabatic Quantum Localization Scenario, 2020, Physical Review Letters
  • Transmission of ALS pathogenesis by the cerebrospinal fluid, 2020, Acta Neuropathologica Communications
  • STochastic Optical Reconstruction Microscopy (STORM) reveals the nanoscale organization of pathological aggregates in human brain, 2020, Neuropathology and Applied Neurobiology

The scientist frequently publishes in journals such as:

  • Neurotherapeutics
  • Journal of Neuroscience
  • Acta Neuropathologica Communications
  • Biomedicines
  • eNeuro

Jean-Pierre Julien collaborates regularly with several colleagues, including Jasna Križ, Hejer Boutej, Daniel J. Phaneuf, Sunny Kumar, and Pierre Cordeau, indicating a consistent engagement with a group of research peers.

Best Publications

  • Preoperative Chemotherapy in Primary Operable Breast Cancer: Results From the European Organization for Research and Treatment of Cancer Trial 10902

    Jos A. Van Der Hage;Cornelis J. H. Van De Velde;Jean-Pierre Julien;Michelle Tubiana-Hulin

  • Wild-type nonneuronal cells extend survival of SOD1 mutant motor neurons in ALS mice.

    A. M. Clement;M. D. Nguyen;E. A. Roberts;E. A. Roberts;M. L. Garcia;M. L. Garcia

  • Innate immunity: the missing link in neuroprotection and neurodegeneration?

    Minh Dang Nguyen;Jean-Pierre Julien;Serge Rivest

  • Risk Factors for Recurrence and Metastasis After Breast-Conserving Therapy for Ductal Carcinoma-In-Situ: Analysis of European Organization for Research and Treatment of Cancer Trial 10853

    N Bijker;J L Peterse;L Duchateau;J P Julien

  • Chromogranin-mediated secretion of mutant superoxide dismutase proteins linked to amyotrophic lateral sclerosis.

    Makoto Urushitani;Attila Sik;Takashi Sakurai;Nobuyuki Nukina

  • Breast-Conserving Treatment With or Without Radiotherapy in Ductal Carcinoma In Situ: 15-Year Recurrence Rates and Outcome After a Recurrence, From the EORTC 10853 Randomized Phase III Trial

    Mila Donker;Saskia Litière;Gustavo Werutsky;Jean Pierre Julien

  • Increasing the dose intensity of chemotherapy by more frequent administration or sequential scheduling: a patient-level meta-analysis of 37 298 women with early breast cancer in 26 randomised trials

    Richard Gray;Rosie Bradley;Jeremy Braybrooke;Zulian Liu

  • Deregulation of TDP-43 in amyotrophic lateral sclerosis triggers nuclear factor κB–mediated pathogenic pathways

    Vivek Swarup;Daniel Phaneuf;Nicolas Dupré;Susanne Petri

  • Extracellular Mutant SOD1 Induces Microglial-Mediated Motoneuron Injury

    Weihua Zhao;David R. Beers;Jenny S. Henkel;Wei Zhang

  • SOD1 mutation is associated with accumulation of neurofilaments in amyotrophic lateral sclerosis.

    Guy A. Rouleau;Arthur W. Clark;Karen Rooke;Albena Pramatarova

  • Pathological hallmarks of amyotrophic lateral sclerosis/frontotemporal lobar degeneration in transgenic mice produced with TDP-43 genomic fragments

    Vivek Swarup;Daniel Phaneuf;Christine Bareil;Janice Robertson

  • A Frameshift Deletion in Peripherin Gene Associated with Amyotrophic Lateral Sclerosis

    François Gros-Louis;Roxanne Larivière;Geneviève Gowing;Sandra Laurent

  • The Src/c-Abl pathway is a potential therapeutic target in amyotrophic lateral sclerosis.

    Keiko Imamura;Yuishin Izumi;Akira Watanabe;Kayoko Tsukita

  • Induction of proinflammatory molecules in mice with amyotrophic lateral sclerosis: No requirement for proapoptotic interleukin-1β in neurodegeneration

    Minh Dang Nguyen;Jean‐Pierre Julien;Serge Rivest

  • CD11b+Ly6G- myeloid cells mediate mechanical inflammatory pain hypersensitivity.

    Nader Ghasemlou;Isaac M. Chiu;Jean-Pierre Julien;Clifford J. Woolf

  • A neurotoxic peripherin splice variant in a mouse model of ALS.

    Janice Robertson;Janice Robertson;Mohammad M. Doroudchi;Minh Dang Nguyen;Heather D. Durham

  • Breast-conserving therapy for Paget disease of the nipple: a prospective European Organization for Research and Treatment of Cancer study of 61 patients

    Nina Bijker;Emiel J.T. Rutgers;Luc Duchateau;Johannes L. Peterse

  • Localization of a toxic form of superoxide dismutase 1 protein to pathologically affected tissues in familial ALS.

    Terrell E. Brotherton;Yingjie Li;Deborah S Cooper;Marla Gearing

  • Misfolded SOD1 pathology in sporadic Amyotrophic Lateral Sclerosis

    Bastien Paré;Manuela Lehmann;Marie Beaudin;Ulrika Nordström

  • Myosin Va binding to neurofilaments is essential for correct myosin Va distribution and transport and neurofilament density

    Mala V. Rao;Linda J. Engle;Panaiyur S. Mohan;Panaiyur S. Mohan;Aidong Yuan;Aidong Yuan

Frequent Co-Authors

Emiel J. Th. Rutgers
Emiel J. Th. Rutgers Antoni van Leeuwenhoek Hospital
Marc J. van de Vijver
Marc J. van de Vijver University of Amsterdam
Johannes L. Peterse
Johannes L. Peterse Antoni van Leeuwenhoek Hospital
Cornelis J.H. van de Velde
Cornelis J.H. van de Velde Leiden University Medical Center
Harry Bartelink
Harry Bartelink Antoni van Leeuwenhoek Hospital
Bernard Asselain
Bernard Asselain Institute Curie
Hein Putter
Hein Putter Leiden University Medical Center

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