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Jacqueline Capeau

Jacqueline Capeau

D-Index & Metrics

Medicine

D-Index
86
Citations
27585
World Ranking
14117
National Ranking
455

Research.com Recognitions

  • 2003 - Member of Academia Europaea

Overview

Jacqueline Capeau is affiliated with Inserm in France and has made substantial contributions within the field of Medicine, with a total of 79 publications. Their subfields of focus include Emergency Medicine, Infectious Diseases, Physiology, Epidemiology, and Virology. Capeau's research interests notably center around HIV-related health complications and treatments, adipokines and inflammation in metabolic diseases, adipose tissue and metabolism, and HIV/AIDS drug development and interventions.

Among their recent published papers are:

  • HIV and antiretroviral therapy-related fat alterations (2020) published in Nature Reviews Disease Primers
  • The Integrase Inhibitors Dolutegravir and Raltegravir Exert Proadipogenic and Profibrotic Effects and Induce Insulin Resistance in Human/Simian Adipose Tissue and Human Adipocytes (2020) published in Clinical Infectious Diseases
  • Metformin alleviates stress-induced cellular senescence of aging human adipose stromal cells and the ensuing adipocyte dysfunction (2021) published in eLife
  • Progerin Expression Induces Inflammation, Oxidative Stress and Senescence in Human Coronary Endothelial Cells (2020) published in Cells
  • Pain in women with knee and/or hip osteoarthritis is related to systemic inflammation and to adipose tissue dysfunction: Cross-sectional results of the KHOALA cohort (2020) published in Seminars in Arthritis and Rheumatism

Capeau has collaborated extensively with several researchers, including Bruno Fève, Claire Lagathu, Jean-Philippe Bastard, Soraya Fellahi, and Christine Katlama. These frequent coauthors have contributed collectively to various research outputs within Capeau's domains of interest.

The scientist's research has been disseminated prominently through key academic venues such as Annales de biologie clinique, AIDS, Cells, Nature Reviews Disease Primers, and Current Opinion in HIV and AIDS. These venues have hosted multiple publications, reflecting the sustained engagement of Capeau in high-impact journals relevant to their field.

Capeau's main topics of research encompass:

  • HIV-related health complications and treatments
  • HIV Research and Treatment
  • Adipokines, Inflammation, and Metabolic Diseases
  • Adipose Tissue and Metabolism
  • HIV/AIDS drug development and treatment
  • HIV/AIDS Research and Interventions
  • Regulation of Appetite and Obesity

In recognition of their scientific contributions, Capeau was named a Member of Academia Europaea in 2003.

Best Publications

  • Recent advances in the relationship between obesity, inflammation, and insulin resistance.

    Jean-Philippe Bastard;Mustapha Maachi;Claire Lagathu;Min Ji Kim

  • Elevated levels of interleukin 6 are reduced in serum and subcutaneous adipose tissue of obese women after weight loss.

    Jean-Philippe Bastard;Claude Jardel;Eric Bruckert;Patricia Blondy

  • Identification of the gene altered in Berardinelli-Seip congenital lipodystrophy on chromosome 11q13.

    Jocelyne Magré;Marc Delépine;Eliane Khallouf;Tobias Gedde-Dahl

  • Association between altered expression of adipogenic factor SREBP1 in lipoatrophic adipose tissue from HIV-1-infected patients and abnormal adipocyte differentiation and insulin resistance

    Jean Philippe Bastard;Martine Caron;Hubert Vidal;Véronique Jan

  • Systemic low-grade inflammation is related to both circulating and adipose tissue TNFalpha, leptin and IL-6 levels in obese women.

    Maachi M;Piéroni L;Bruckert E;Jardel C

  • Chronic interleukin-6 (IL-6) treatment increased IL-6 secretion and induced insulin resistance in adipocyte: prevention by rosiglitazone

    Claire Lagathu;Jean-Philippe Bastard;Martine Auclair;Mustapha Maachi

  • Insulin and IGF-1 stimulate the β-catenin pathway through two signalling cascades involving GSK-3β inhibition and Ras activation

    Christèle Desbois-Mouthon;Axelle Cadoret;Marie-José Blivet-Van Eggelpoël

  • Association of a homozygous nonsense caveolin-1 mutation with Berardinelli-Seip congenital lipodystrophy.

    C. A. Kim;Marc Delépine;Emilie Boutet;Haquima El Mourabit

  • Serum leptin level is a regulator of bone mass

    F. Elefteriou;S. Takeda;S. Takeda;K. Ebihara;J. Magre

  • The HIV Protease Inhibitor Indinavir Impairs Sterol Regulatory Element-Binding Protein-1 Intranuclear Localization, Inhibits Preadipocyte Differentiation, and Induces Insulin Resistance

    Martine Caron;Martine Auclair;Corinne Vigouroux;Martine Glorian

  • Long-term treatment with interleukin-1β induces insulin resistance in murine and human adipocytes

    C. Lagathu;L. Yvan-Charvet;J.-P. Bastard;M. Maachi

  • The lipogenic transcription factor ChREBP dissociates hepatic steatosis from insulin resistance in mice and humans

    Fadila Benhamed;Pierre-Damien Denechaud;Maud Lemoine;Céline Robichon

  • Nuclear envelope disorganization in fibroblasts from lipodystrophic patients with heterozygous R482Q/W mutations in the lamin A/C gene

    Corinne Vigouroux;Martine Auclair;Emmanuelle Dubosclard;Marcel Pouchelet

  • HIV and coronary heart disease: time for a better understanding.

    Franck Boccara;Sylvie Lang;Catherine Meuleman;Stephane Ederhy

  • Perilipin Deficiency and Autosomal Dominant Partial Lipodystrophy

    Sheetal Gandotra;Caroline Le Dour;William Bottomley;Pascale Cervera

  • Serum adipocytokines are related to lipodystrophy and metabolic disorders in HIV-infected men under antiretroviral therapy.

    Corinne Vigouroux;Mustapha Maachi;Thu-Huyen Nguyên;Christiane Coussieu

  • Ten-year diabetes incidence in 1046 HIV-infected patients started on a combination antiretroviral treatment.

    Capeau J;Bouteloup;Katlama C;Bastard Jp

  • How can we measure insulin sensitivity/resistance?

    B. Antuna-Puente;E. Disse;R. Rabasa-Lhoret;M. Laville

  • Human lipodystrophies linked to mutations in A-type lamins and to HIV protease inhibitor therapy are both associated with prelamin A accumulation, oxidative stress and premature cellular senescence

    M Caron;M Caron;M Auclair;M Auclair;B Donadille;B Donadille;V Béréziat;V Béréziat

  • Lamin A/C gene: Sex-determined expression of mutations in dunnigan-type familial partial lipodystrophy and absence of coding mutations in congenital and acquired generalized lipoatrophy

    Corinne Vigouroux;Jocelyne Magre;Marie-Christine Vantyghem;Charlotte Bourut

Frequent Co-Authors

Jean Dubuisson
Jean Dubuisson Institut Pasteur
Christian Gespach
Christian Gespach Sorbonne University
Fabrice Carrat
Fabrice Carrat Sorbonne University
Patrice Cacoub
Patrice Cacoub Sorbonne University
Francis Berenbaum
Francis Berenbaum Université Paris Cité
Bertrand Cariou
Bertrand Cariou University of Nantes
Christine Katlama
Christine Katlama Sorbonne University
Charles Coutelle
Charles Coutelle Imperial College London

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