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D-Index & Metrics

Molecular Biology

D-Index
61
Citations
11998
World Ranking
1914
National Ranking
57

Overview

Igor Stagljar is affiliated with the University of Toronto in Canada and focuses their research primarily in the fields of biochemistry, genetics, and molecular biology, with significant contributions to medicine. Their scholarly output includes 53 publications in biochemistry, genetics, and molecular biology, and 35 in medicine.

Their research spans key subfields including molecular biology, cell biology, infectious diseases, oncology, and plant science. This multidisciplinary approach encompasses a range of biological topics and systems. Among the main topics covered by their work are protein degradation and inhibitors, SARS-CoV-2 detection and testing, PI3K/AKT/mTOR signaling in cancer, microtubule and mitosis dynamics, SARS-CoV-2 and COVID-19 research, nematode management and characterization studies, along with ubiquitin and proteasome pathways.

Stagljar has coauthored numerous publications with several researchers, frequently collaborating with:

  • Jamie Snider (32 joint publications)
  • Zhong Yao (20 joint publications)
  • Anna Lyakisheva (13 joint publications)
  • Victoria Wong (12 joint publications)
  • Farzaneh Aboualizadeh (9 joint publications)

Their work has been published in prominent scientific venues including:

  • bioRxiv (Cold Spring Harbor Laboratory) with 8 publications
  • Nature Communications with 7 publications
  • Journal of Molecular Biology with 4 publications
  • Molecular Systems Biology with 3 publications
  • Biochemical and Biophysical Research Communications with 2 publications

Recent papers by Igor Stagljar cover a variety of topics within their research interests. Notable publications include:

  • "Receptor tyrosine kinases and cancer: oncogenic mechanisms and therapeutic approaches," 2021, Oncogene
  • "Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRASG13D," 2020, Nature Communications
  • "A homogeneous split-luciferase assay for rapid and sensitive detection of anti-SARS CoV-2 antibodies," 2021, Nature Communications
  • "Split Intein-Mediated Protein Ligation for detecting protein-protein interactions and their inhibition," 2020, Nature Communications
  • "Selective control of parasitic nematodes using bioactivated nematicides," 2023, Nature

Best Publications

  • A global genetic interaction network maps a wiring diagram of cellular function

    Michael Costanzo;Benjamin VanderSluis;Elizabeth N. Koch;Anastasia Baryshnikova

  • A genetic system based on split-ubiquitin for the analysis of interactions between membrane proteins in vivo

    Igor Stagljar;Chantal Korostensky;Nils Johnsson;Stephan te Heesen

  • Large-scale identification of yeast integral membrane protein interactions

    John P. Miller;Russell S. Lo;Asa Ben-Hur;Cynthia Desmarais

  • Interaction of the type IIa Na/Pi cotransporter with PDZ proteins.

    Serge M. Gisler;Igor Stagljar;Martin Traebert;Desa Bacic

  • Fundamentals of protein interaction network mapping

    Jamie Snider;Max Kotlyar;Punit Saraon;Zhong Yao

  • Interaction landscape of membrane - protein complexes in Saccharomyces cerevisiae

    Mohan Babu;James Vlasblom;Shuye Pu;Xinghua Guo

  • ABC Transporters in Saccharomyces cerevisiae and Their Interactors: New Technology Advances the Biology of the ABCC (MRP) Subfamily

    Christian M. Paumi;Matthew Chuk;Jamie Snider;Igor Stagljar

  • SAF-B protein couples transcription and pre-mRNA splicing to SAR/MAR elements

    Oliver Nayler;Wolf Strätling;Jean-Pierre Bourquin;Igor Stagljar

  • Regulation of Epidermal Growth Factor Receptor Trafficking by Lysine Deacetylase HDAC6

    Yonathan Lissanu Deribe;Philipp Wild;Akhila Chandrashaker;Jasna Curak

  • Chaperone Control of the Activity and Specificity of the Histone H3 Acetyltransferase Rtt109

    Jeffrey Fillingham;Judith Recht;Andrea C. Silva;Bernhard Suter

  • Regulation of CD133 by HDAC6 Promotes β-Catenin Signaling to Suppress Cancer Cell Differentiation

    Anthony B. Mak;Allison M.L. Nixon;Saranya Kittanakom;Jocelyn M. Stewart;Jocelyn M. Stewart

  • The post-genomic era of interactive proteomics: Facts and perspectives

    Daniel Auerbach;Safia Thaminy;Michael O. Hottiger;Igor Stagljar

  • The mammalian-membrane two-hybrid assay (MaMTH) for probing membrane-protein interactions in human cells

    Julia Petschnigg;Bella Groisman;Max Kotlyar;Mikko Taipale

  • Two-hybrid technologies in proteomics research.

    Bernhard Suter;Saranya Kittanakom;Igor Stagljar

  • Detecting interactions with membrane proteins using a membrane two-hybrid assay in yeast

    Jamie Snider;Saranya Kittanakom;Dunja Damjanovic;Jasna Curak

  • In silico prediction of physical protein interactions and characterization of interactome orphans

    Max Kotlyar;Chiara Pastrello;Flavia Pivetta;Alessandra Lo Sardo

  • Identification of Novel ErbB3-Interacting Factors Using the Split-Ubiquitin Membrane Yeast Two-Hybrid System

    Safia Thaminy;Daniel Auerbach;Anthony Arnoldo;Igor Stagljar

  • The human Rothmund-Thomson syndrome gene product, RECQL4, localizes to distinct nuclear foci that coincide with proteins involved in the maintenance of genome stability

    Maja Petkovic;Tobias Dietschy;Raimundo Freire;Renjie Jiao

  • Mapping Protein-Protein Interactions for the Yeast ABC Transporter Ycf1p by Integrated Split-Ubiquitin Membrane Yeast Two-Hybrid Analysis

    Christian M. Paumi;Javier Menendez;Anthony Arnoldo;Kim Engels

  • Analysis of membrane protein interactions using yeast-based technologies

    Igor Stagljar;Stanley Fields

Frequent Co-Authors

Igor Jurisica
Igor Jurisica University Health Network
Michael O. Hottiger
Michael O. Hottiger University of Zurich
Francisco Ciruela
Francisco Ciruela University of Barcelona
Ian D. Hickson
Ian D. Hickson University of Copenhagen
Anne-Claude Gingras
Anne-Claude Gingras Lunenfeld-Tanenbaum Research Institute
Charles Boone
Charles Boone University of Toronto
Corey Nislow
Corey Nislow University of British Columbia
Frederick P. Roth
Frederick P. Roth Lunenfeld-Tanenbaum Research Institute
Thomas Kislinger
Thomas Kislinger University of Toronto

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