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Hiroshi Hashimoto

Hiroshi Hashimoto

D-Index & Metrics

Immunology

D-Index
67
Citations
13036
World Ranking
2702
National Ranking
110

Overview

Hiroshi Hashimoto is affiliated with Juntendo University in Japan and has contributed extensively to research primarily within the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work spans multiple subfields of study, including Molecular Biology, Pulmonary and Respiratory Medicine, Genetics, Pharmacology, and Oncology.

The scientist has published research in several prominent venues, with frequent publications in The Journal of Biochemistry, Cancers, Journal of Biological Chemistry, Journal of the American Chemical Society, and Biochemistry.

Research topics covered by Hashimoto's work focus notably on DNA Repair Mechanisms, Genomics and Chromatin Dynamics, Vasculitis and related conditions, Lung Cancer Diagnosis and Treatment, CRISPR and Genetic Engineering, Microbial Natural Products and Biosynthesis, as well as Bacterial Genetics and Biotechnology.

Some of the recent scientific articles associated with this researcher include:

  • Catalytic mechanism and endo-to-exo selectivity reversion of an octalin-forming natural Diels-Alderase, 2021, Nature Catalysis
  • Development of a DNA aptamer that binds to the complementarity-determining region of therapeutic monoclonal antibody and affinity improvement induced by pH-change for sensitive detection, 2022, Biosensors and Bioelectronics
  • Specialized Flavoprotein Promotes Sulfur Migration and Spiroaminal Formation in Aspirochlorine Biosynthesis, 2020, Journal of the American Chemical Society
  • Reconstruction of a three-dimensional color-video of a point-cloud object using the projection-type holographic display with a holographic optical element, 2020, Optics Express
  • Propolis Components and Biological Activities from Stingless Bees Collected on South Sulawesi, Indonesia, 2020, HAYATI Journal of Biosciences

Collaborative work with other researchers is a notable aspect of Hashimoto's career, with frequent co-authors including Kodai Hara, Asami Hishiki, Kenji Watanabe, Haruhisa Matsuguma, and Mingyon Mun.

Best Publications

  • Fc gamma receptor gene polymorphisms in Japanese patients with systemic lupus erythematosus - Contribution of FCGR2B to genetic susceptibility

    Chieko Kyogoku;Hilde M. Dijstelbloem;Naoyuki Tsuchiya;Yoko Hatta

  • Critical Roles of TRAF2 and TRAF5 in Tumor Necrosis Factor-induced NF-κB Activation and Protection from Cell Death

    Kurisu Tada;Tatsuma Okazaki;Sachiko Sakon;Tomonari Kobarai

  • Sex-specific association of X-linked Toll-like receptor 7 (TLR7) with male systemic lupus erythematosus

    Nan Shen;Qiong Fu;Qiong Fu;Yun Deng;Yun Deng;Xiaoxia Qian

  • The soluble CD40 ligand sCD154 in systemic lupus erythematosus

    Kazunori Kato;Ernesto Santana-Sahagún;Laura Z. Rassenti;Michael H. Weisman

  • Suppression of collagen-induced arthritis by natural killer T cell activation with OCH, a sphingosine-truncated analog of α-galactosylceramide

    Asako Chiba;Shinji Oki;Katsuichi Miyamoto;Hiroshi Hashimoto

  • The liver in collagen diseases: pathologic study of 160 cases with particular reference to hepatic arteritis, primary biliary cirrhosis, autoimmune hepatitis and nodular regenerative hyperplasia of the liver

    Toshiharu Matsumoto;Shigeto Kobayashi;Hidetaka Shimizu;Mikako Nakajima

  • Levels of IL-12 in the sera of patients with systemic lupus erythematosus (SLE)—relation to Th1- and Th2-derived cytokines

    Y. Tokano;S. Morimoto;H. Kaneko;H. Amano

  • Nucleotide sequence of feline immunodeficiency virus: classification of Japanese isolates into two subtypes which are distinct from non-Japanese subtypes.

    S Kakinuma;K Motokawa;T Hohdatsu;J K Yamamoto

  • Whole genome association study of rheumatoid arthritis using 27 039 microsatellites

    Gen Tamiya;Gen Tamiya;Minori Shinya;Minori Shinya;Tadashi Imanishi;Tomoki Ikuta;Tomoki Ikuta

  • A multicenter, double-blind, randomized, placebo controlled trial of infliximab combined with low dose methotrexate in Japanese patients with rheumatoid arthritis.

    Tohru Abe;Tsutomu Takeuchi;Nobuyuki Miyasaka;Hiroshi Hashimoto

  • Accuracy of cerebrospinal fluid IL-6 testing for diagnosis of lupus psychosis. A multicenter retrospective study.

    Shunsei Hirohata;Yoshinori Kanai;Akiko Mitsuo;Yoshiaki Tokano

  • Analysis on the association of human BLYS (BAFF, TNFSF13B) polymorphisms with systemic lupus erythematosus and rheumatoid arthritis.

    A Kawasaki;N Tsuchiya;T Fukazawa;H Hashimoto

  • Efficacy and safety of tacrolimus for lupus nephritis: a placebo-controlled double-blind multicenter study.

    Nobuyuki Miyasaka;Shinichi Kawai;Hiroshi Hashimoto

  • Antiglycolipid autoantibody detected in the sera from systemic lupus erythematosus patients.

    T Hirano;H Hashimoto;Y Shiokawa;M Iwamori

  • Expression and function of fibronectin binding integrins on rat mast cells

    Masahiko Yasuda;Yukihito Hasunuma;Hiroyasu Adachi;Chiyoko Sekine

  • Cytomegalovirus infection in patients with systemic lupus erythematosus.

    Iwao Sekigawa;M. Nawata;N. Seta;M. Yamada

  • Role of STAT4 polymorphisms in systemic lupus erythematosus in a Japanese population: a case-control association study of the STAT1-STAT4 region.

    Aya Kawasaki;Ikue Ito;Koki Hikami;Jun Ohashi

  • Comparison of the amino acid sequence and phylogenetic analysis of the peplomer, integral membrane and nucleocapsid proteins of feline, canine and porcine coronaviruses.

    Kenji Motokawa;Tsutomu Hohdatsu;Hiroshi Hashimoto;Hiroyuki Koyama

  • Apoptosis of lymphocytes induced by glucocorticoids and relationship to therapeutic efficacy in patients with systemic lupus erythematosus

    Manami Seki;Chifuyu Ushiyama;Noriyuki Seta;Kaori Abe

  • Association of IRF5 polymorphisms with systemic lupus erythematosus in a Japanese population: support for a crucial role of intron 1 polymorphisms.

    Aya Kawasaki;Chieko Kyogoku;Jun Ohashi;Risa Miyashita

  • CD134L Engagement Enhances Human B Cell Ig Production: CD154/CD40, CD70/CD27, and CD134/CD134L Interactions Coordinately Regulate T Cell-Dependent B Cell Responses

    Shinji Morimoto;Yumiko Kanno;Yuetsu Tanaka;Yoshiaki Tokano

Frequent Co-Authors

Yoshinari Takasaki
Yoshinari Takasaki Juntendo University
Naoyuki Tsuchiya
Naoyuki Tsuchiya University of Tsukuba
Ko Okumura
Ko Okumura Juntendo University
Takayuki Sumida
Takayuki Sumida University of Tsukuba
Katsushi Tokunaga
Katsushi Tokunaga University of Tokyo
Kazuo Suzuki
Kazuo Suzuki Teikyo University
Hideo Yagita
Hideo Yagita Juntendo University
Nobuyuki Miyasaka
Nobuyuki Miyasaka Tokyo Medical and Dental University
Toshikazu Shirai
Toshikazu Shirai Juntendo University
Hirofumi Makino
Hirofumi Makino Okayama University

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