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D-Index & Metrics

Molecular Biology

D-Index
48
Citations
8734
World Ranking
2683
National Ranking
201

Overview

Hiroki Sasaki is affiliated with the National Cancer Centre in Japan and has contributed extensively to research in medicine and biochemistry, genetics, and molecular biology. Their scientific work primarily spans the fields of molecular biology, pulmonary and respiratory medicine, oncology, cancer research, and surgery.

The research topics covered by Sasaki include interstitial lung diseases and idiopathic pulmonary fibrosis, esophageal cancer research and treatment, sarcoidosis and beryllium toxicity research, RNA modifications and cancer, cancer-related gene regulation, cancer-related molecular mechanisms research, and cancer cells and metastasis.

Recent publications by Sasaki include:

  • Multi-omic profiling of peritoneal metastases in gastric cancer identifies molecular subtypes and therapeutic vulnerabilities, 2021, Nature Cancer
  • Molecular Network Profiling in Intestinal- and Diffuse-Type Gastric Cancer, 2020, Cancers
  • ARHGAP-RhoA signaling provokes homotypic adhesion-triggered cell death of metastasized diffuse-type gastric cancer, 2022, Oncogene
  • The potential utility of anterior upper lobe honeycomb-like lesion in interstitial lung disease associated with connective tissue disease, 2020, Respiratory Medicine
  • Report of the use of patient-derived xenograft models in the development of anticancer drugs in Japan, 2020, Cancer Science

Frequent co-authors of Sasaki include Hiroshi Yokozaki, Sabina Quader, Ryuichi Ono, Horacio Cabral, and Kazuhiko Aoyagi.

Key venues where Sasaki has published multiple works include the Proceedings for Annual Meeting of The Japanese Pharmacological Society, Journal of Clinical Oncology, Preprints.org, Cancers, and Oncogene.

Best Publications

  • Relation between microRNA expression and progression and prognosis of gastric cancer: a microRNA expression analysis

    Tetsuya Ueda;Tetsuya Ueda;Stefano Volinia;Stefano Volinia;Hiroshi Okumura;Hiroshi Okumura;Masayoshi Shimizu

  • Genetic variation in PSCA is associated with susceptibility to diffuse-type gastric cancer.

    Hiromi Sakamoto;Kimio Yoshimura;Norihisa Saeki

  • Integrative genomics identifies LMO1 as a neuroblastoma oncogene

    Kai Wang;Kai Wang;Sharon J. Diskin;Haitao Zhang;Edward F. Attiyeh

  • Distinctive expression and function of four GSDM family genes (GSDMA-D) in normal and malignant upper gastrointestinal epithelium.

    Norihisa Saeki;Takebumi Usui;Kazuhiko Aoyagi;Dal Ho Kim

  • Gasdermin (Gsdm) localizing to mouse Chromosome 11 is predominantly expressed in upper gastrointestinal tract but significantly suppressed in human gastric cancer cells.

    Norihisa Saeki;Yoshitaka Kuwahara;Hiroki Sasaki;Hajime Satoh

  • Direct hepatic fate specification from mouse embryonic stem cells

    Takumi Teratani;Hanako Yamamoto;Kazuhiko Aoyagi;Hiroki Sasaki

  • NRF2 Mutation Confers Malignant Potential and Resistance to Chemoradiation Therapy in Advanced Esophageal Squamous Cancer

    Tatsuhiro Shibata;Akiko Kokubu;Shigeru Saito;Mako Narisawa-Saito

  • Discovery of Aberrant Expression of R-RAS by Cancer-Linked DNA Hypomethylation in Gastric Cancer Using Microarrays

    Michiko Nishigaki;Kazuhiko Aoyagi;Inaho Danjoh;Masahide Fukaya

  • Absence of endothelial cells, central necrosis, and fibrosis are associated with aggressive inflammatory breast cancer.

    Kazuo Shirakawa;Hitoshi Tsuda;Yuji Heike;Kazunori Kato

  • Podoplanin-Positive Fibroblasts Enhance Lung Adenocarcinoma Tumor Formation: Podoplanin in Fibroblast Functions for Tumor Progression

    Ayuko Hoshino;Genichiro Ishii;Takashi Ito;Kazuhiko Aoyagi

  • AZD2171 Shows Potent Antitumor Activity Against Gastric Cancer Over-Expressing Fibroblast Growth Factor Receptor 2/Keratinocyte Growth Factor Receptor

    Masayuki Takeda;Tokuzo Arao;Hideyuki Yokote;Teruo Komatsu

  • Hedgehog Signal Activation in Gastric Pit Cell and in Diffuse-Type Gastric Cancer

    Masahide Fukaya;Noriyuki Isohata;Hiroyuki Ohta;Kazuhiko Aoyagi

  • Biological properties and gene expression associated with metastatic potential of human osteosarcoma

    Tetsuhiro Nakano;Masachika Tani;Yasunori Ishibashi;Kenji Kimura

  • Genes preferentially expressed in embryo stomach are predominantly expressed in gastric cancer.

    Masamitsu Tanaka;Hiroki Sasaki;Isamu Kino;Takashi Sugimura

  • A Functional Single Nucleotide Polymorphism in Mucin 1, at Chromosome 1q22, Determines Susceptibility to Diffuse-Type Gastric Cancer

    Norihisa Saeki;Akira Saito;Il Ju Choi;Keitaro Matsuo

  • A faithful method for PCR-mediated global mRNA amplification and its integration into microarray analysis on laser-captured cells.

    Kazuhiko Aoyagi;Takeshi Tatsuta;Michiko Nishigaki;Shingo Akimoto

  • Evaluation of a whole-genome amplification method based on adaptor-ligation PCR of randomly sheared genomic DNA.

    Chikako Tanabe;Kazuhiko Aoyagi;Tokuki Sakiyama;Takashi Kohno

  • High miR‐21 expression from FFPE tissues is associated with poor survival and response to adjuvant chemotherapy in colon cancer

    Naohide Oue;Katsuhiro Anami;Aaron J. Schetter;Markus Moehler

  • Mutation Frequency of the p16/CDKN2 Gene in Primary Cancers in the Upper Digestive Tract

    Hiroyasu Igaki;Hiroki Sasaki;Yuji Tachimori;Hoichi Kato

  • Gene amplification profiling of esophageal squamous cell carcinomas by DNA array CGH.

    Tomoki Ishizuka;Chikako Tanabe;Hiromi Sakamoto;Kazuhiko Aoyagi

Frequent Co-Authors

Teruhiko Yoshida
Teruhiko Yoshida National Cancer Research Institute, UK
Masaaki Terada
Masaaki Terada National Cancer Research Institute, UK
Hiromi Sakamoto
Hiromi Sakamoto National Cancer Research Institute, UK
Atsushi Ochiai
Atsushi Ochiai University of Tokyo
Wataru Yasui
Wataru Yasui Hiroshima University
Takashi Sugimura
Takashi Sugimura National Cancer Centre
Takahiro Ochiya
Takahiro Ochiya Tokyo Medical University
Takashi Ito
Takashi Ito Kyushu University
Jun Yokota
Jun Yokota National Cancer Centre
Hitoshi Katai
Hitoshi Katai Juntendo University

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