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Molecular Biology

D-Index
43
Citations
9704
World Ranking
2960
National Ranking
55

Overview

Guglielmo Roma is a researcher affiliated with Novartis (Switzerland) based in Switzerland. The primary fields of study for their research include Biochemistry, Genetics and Molecular Biology as well as Medicine. Their work spans various subfields such as Molecular Biology, Neurology, Immunology, Epidemiology, and Hepatology.

Their research topics cover several specialized areas, including:

  • Renal and related cancers
  • Single-cell and spatial transcriptomics
  • Liver Disease Diagnosis and Treatment
  • Liver physiology and pathology
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Wnt/β-catenin signaling in development and cancer
  • CRISPR and Genetic Engineering

Among their recent scientific publications are:

  • Cell Types of the Human Retina and Its Organoids at Single-Cell Resolution, 2020, Cell
  • Immune cell landscaping reveals a protective role for regulatory T cells during kidney injury and fibrosis, 2020, JCI Insight
  • An orally available, brain penetrant, small molecule lowers huntingtin levels by enhancing pseudoexon inclusion, 2022, Nature Communications
  • Fast and highly sensitive full-length single-cell RNA sequencing using FLASH-seq, 2022, Nature Biotechnology
  • Single-cell and bulk transcriptomics of the liver reveals potential targets of NASH with fibrosis, 2021, Scientific Reports

Frequent collaborators in their research include Annick Waldt, Sven Schuierer, Walter Carbone, Rachel Cuttat, and Judith Knehr. These individuals have co-authored multiple publications alongside Guglielmo Roma.

The most common publication venues for their work are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Cell stem cell
  • iScience
  • Nature Chemical Biology

Best Publications

  • A single-cell atlas of the airway epithelium reveals the CFTR-rich pulmonary ionocyte

    Lindsey W. Plasschaert;Rapolas Žilionis;Rapolas Žilionis;Rayman Choo-Wing;Virginia Savova

  • The genome of melon (Cucumis melo L.)

    Jordi Garcia-Mas;Andrej Benjak;Walter Sanseverino;Michael Bourgeois

  • Cell Types of the Human Retina and Its Organoids at Single-Cell Resolution.

    Cameron S. Cowan;Magdalena Renner;Magdalena Renner;Martina De Gennaro;Brigitte Gross-Scherf

  • Self-organization and symmetry breaking in intestinal organoid development

    Denise Serra;Denise Serra;Urs Mayr;Urs Mayr;Andrea Boni;Andrea Boni;Ilya Lukonin;Ilya Lukonin

  • SMN2 splice modulators enhance U1-pre-mRNA association and rescue SMA mice

    James Palacino;Susanne E Swalley;Cheng Song;Atwood K Cheung

  • Nonoverlapping Functions of the Polycomb Group Cbx Family of Proteins in Embryonic Stem Cells

    Lluis Morey;Gloria Pascual;Luca Cozzuto;Guglielmo Roma

  • YAP1 Exerts Its Transcriptional Control via TEAD-Mediated Activation of Enhancers

    Claudia Stein;Anaïs Flore Bardet;Guglielmo Roma;Sebastian Bergling

  • The RSPO-LGR4/5-ZNRF3/RNF43 module controls liver zonation and size.

    Lara Planas-Paz;Vanessa Orsini;Luke Boulter;Diego Calabrese

  • Extreme genomic erosion after recurrent demographic bottlenecks in the highly endangered Iberian lynx.

    Federico Abascal;André Corvelo;Fernando Cruz;Fernando Cruz;José L. Villanueva-Cañas

  • Sulfatases and sulfatase modifying factors: an exclusive and promiscuous relationship

    M. Sardiello;I. Annunziata;G. Roma;A. Ballabio

  • PRGdb: a bioinformatics platform for plant resistance gene analysis.

    Walter Sanseverino;Guglielmo Roma;Marco De Simone;Luigi Faino

  • Age-associated inflammation inhibits epidermal stem cell function

    Jason Doles;Mekayla Storer;Luca Cozzuto;Guglielmo Roma;Guglielmo Roma

  • Regulation of Human Epidermal Stem Cell Proliferation and Senescence Requires Polycomb- Dependent and -Independent Functions of Cbx4

    Nuno Miguel Luis;Lluis Morey;Stefania Mejetta;Gloria Pascual

  • YAP, but Not RSPO-LGR4/5, Signaling in Biliary Epithelial Cells Promotes a Ductular Reaction in Response to Liver Injury.

    Lara Planas-Paz;Tianliang Sun;Monika Pikiolek;Nadire R. Cochran

  • CLK2 inhibition ameliorates autistic features associated with SHANK3 deficiency

    Michael Bidinosti;Paolo Botta;Sebastian Krüttner;Catia C. Proenca

  • Age-Related Gene Expression Signature in Rats Demonstrate Early, Late, and Linear Transcriptional Changes from Multiple Tissues.

    Tea Shavlakadze;Melody Morris;Jian Fang;Sharon X. Wang

  • AXIN2+ Pericentral Hepatocytes Have Limited Contributions to Liver Homeostasis and Regeneration.

    Tianliang Sun;Monika Pikiolek;Vanessa Orsini;Sebastian Bergling

  • Functional CRISPR screening identifies the ufmylation pathway as a regulator of SQSTM1/p62

    Rowena DeJesus;Francesca Moretti;Gregory McAllister;Zuncai Wang

  • A comprehensive assessment of RNA-seq protocols for degraded and low-quantity samples.

    Sven Schuierer;Walter Carbone;Judith Knehr;Virginie Petitjean

  • Cell types of the human retina and its organoids at single-cell resolution: developmental convergence, transcriptomic identity, and disease map

    Cameron Cowan;Magdalena Renner;Magdalena Renner;Martina De Gennaro;Brigitte Gross-Scherf

Frequent Co-Authors

Tewis Bouwmeester
Tewis Bouwmeester Novartis (Switzerland)
Charlotte K.Y. Ng
Charlotte K.Y. Ng Humanitas University
Salvatore Piscuoglio
Salvatore Piscuoglio Humanitas University
Luigi Terracciano
Luigi Terracciano University Hospital of Basel
Michael B. Stadler
Michael B. Stadler Friedrich Miescher Institute
Clemens H. M. Kocken
Clemens H. M. Kocken Biomedical Primate Research Centre
Markus Schirle
Markus Schirle Novartis (Switzerland)
Botond Roska
Botond Roska University of Basel
Jetsumon Sattabongkot
Jetsumon Sattabongkot Mahidol University
Dirk Schübeler
Dirk Schübeler Friedrich Miescher Institute

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