2018 - Fellow of American Physical Society (APS) Citation For contributions at the intersection of physics and life sciences, including PET, electrophoresis, and statistical methods for microarrays For discovering and characterizing proteins involved in DNA repair and developing instrumentation for assessing toxicity associated with cancer chemotherapy
His primary areas of investigation include DNA repair, Molecular biology, DNA damage, DNA and Cell biology. His DNA repair research is classified as research in Gene. His research investigates the connection between Molecular biology and topics such as DNA polymerase mu that intersect with issues in Ku Protein, VJ recombination, Ku80, HMG-box and Replication protein A.
Gilbert Chu has researched DNA in several fields, including Cell cycle and Cell culture. He interconnects Biochemistry, Electroporation and Transfection in the investigation of issues within Cell biology. His Nucleotide excision repair study deals with the bigger picture of Genetics.
Gilbert Chu mainly focuses on Molecular biology, DNA, DNA repair, DNA damage and Gene. His Molecular biology research integrates issues from Damaged DNA binding, Xeroderma pigmentosum, VJ recombination, DNA repair protein XRCC4 and DNA ligase. In his study, Cell cycle is strongly linked to Cell biology, which falls under the umbrella field of DNA.
Gilbert Chu specializes in DNA repair, namely Nucleotide excision repair. The concepts of his Nucleotide excision repair study are interwoven with issues in Photolyase and Saccharomyces cerevisiae. His Gene research is under the purview of Genetics.
His main research concerns DNA repair, Molecular biology, Cancer research, DNA and Cancer. DNA repair is a primary field of his research addressed under Genetics. The study of Molecular biology is intertwined with the study of Nucleotide excision repair in a number of ways.
Gene is closely connected to Basal in his research, which is encompassed under the umbrella topic of Nucleotide excision repair. Gilbert Chu combines subjects such as Colorectal cancer, Polymerase and Homologous recombination with his study of Cancer research. His DNA research is multidisciplinary, relying on both Cleavage, Protein subunit, Recombination and Protein kinase A.
The scientist’s investigation covers issues in Cancer, DNA repair, Function, Genetics and Spinal arthrodesis. His work on Multiple cancer as part of general Cancer research is often related to Patient data and Pembrolizumab, thus linking different fields of science. DNA repair is a subfield of Gene that Gilbert Chu investigates.
His studies deal with areas such as Cell, Haematopoiesis, Transcriptome, False discovery rate and Computational biology as well as Function. All of his Genetics and Single-cell analysis, Stem cell, Regulation of gene expression and Cell type investigations are sub-components of the entire Genetics study. Spinal arthrodesis is integrated with Surgery, Incidence, Randomized controlled trial, Confidence interval and Rate ratio in his study.
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Significance analysis of microarrays applied to the ionizing radiation response
Virginia Goss Tusher;Robert Tibshirani;Gilbert Chu.
Proceedings of the National Academy of Sciences of the United States of America (2001)
Diagnosis of multiple cancer types by shrunken centroids of gene expression
Robert Tibshirani;Trevor Hastie;Balasubramanian Narasimhan;Gilbert Chu.
Proceedings of the National Academy of Sciences of the United States of America (2002)
Separation of large DNA molecules by contour-clamped homogeneous electric fields
Gilbert Chu;Douglas Vollrath;Ronald W. Davis.
Science (1986)
Electroporation for the efficient transfection of mammalian cells with DNA.
Gilbert Chu;Hiroshi Hayakawa;Paul Berg.
Nucleic Acids Research (1987)
Cellular responses to cisplatin. The roles of DNA-binding proteins and DNA repair.
G Chu.
Journal of Biological Chemistry (1994)
Expression of the p48 xeroderma pigmentosum gene is p53-dependent and is involved in global genomic repair
Byung Joon Hwang;James M. Ford;Philip C. Hanawalt;Gilbert Chu.
Proceedings of the National Academy of Sciences of the United States of America (1999)
UV-Induced Ubiquitylation of XPC Protein Mediated by UV-DDB-Ubiquitin Ligase Complex
Kaoru Sugasawa;Yuki Okuda;Masafumi Saijo;Ryotaro Nishi.
Cell (2005)
Class Prediction by Nearest Shrunken Centroids, with Applications to DNA Microarrays
Robert Tibshirani;Trevor Hastie;Balasubramanian Narasimhan;Gilbert Chu.
Statistical Science (2003)
Xeroderma pigmentosum group E cells lack a nuclear factor that binds to damaged DNA
Gilbert Chu;Elaine Chang.
Science (1988)
Synapsis of DNA ends by DNA‐dependent protein kinase
Lisa G. DeFazio;Rachel M. Stansel;Rachel M. Stansel;Jack D. Griffith;Gilbert Chu.
The EMBO Journal (2002)
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