World's Best Scientists 2026 revealed!
George T. Macfarlane

George T. Macfarlane

D-Index & Metrics

Microbiology

D-Index
88
Citations
38349
World Ranking
744
National Ranking
72

Overview

What is he best known for?

The fields of study he is best known for:

  • Internal medicine
  • Biochemistry
  • Enzyme

Fermentation, Biochemistry, Microbiology, Bifidobacterium and Prebiotic are his primary areas of study. The concepts of his Fermentation study are interwoven with issues in Digestion and Propionate. His Propionate research incorporates themes from Protein digestion, Butyrate and Microbial metabolism.

His specific area of interest is Biochemistry, where George T. Macfarlane studies Lipid metabolism. His work in Microbiology covers topics such as Bacteroides which are related to areas like Clostridium and Clostridia. George T. Macfarlane has researched Prebiotic in several fields, including Human nutrition and Inulin.

His most cited work include:

  • Regulation of short-chain fatty acid production (988 citations)
  • Characterization of Bacterial Communities in Feces from Healthy Elderly Volunteers and Hospitalized Elderly Patients by Using Real-Time PCR and Effects of Antibiotic Treatment on the Fecal Microbiota (567 citations)
  • Bacterial metabolism and health-related effects of galacto-oligosaccharides and other prebiotics (557 citations)

What are the main themes of his work throughout his whole career to date?

George T. Macfarlane spends much of his time researching Microbiology, Immunology, Internal medicine, Ulcerative colitis and Inflammatory bowel disease. His studies deal with areas such as 16S ribosomal RNA, Bacteroides, Large intestine, Biofilm and Mucin as well as Microbiology. His Immunology research incorporates elements of Intestinal mucosa, Gastrointestinal tract, Bifidobacterium and Diarrhea.

His work carried out in the field of Bifidobacterium brings together such families of science as Gut flora and Feces. His Ulcerative colitis research includes themes of Mucous membrane and Colitis. As a part of the same scientific family, he mostly works in the field of Inflammatory bowel disease, focusing on Synbiotics and, on occasion, Crohn's disease.

He most often published in these fields:

  • Microbiology (46.15%)
  • Immunology (25.64%)
  • Internal medicine (20.51%)

What were the highlights of his more recent work (between 2007-2015)?

  • Immunology (25.64%)
  • Microbiology (46.15%)
  • Ulcerative colitis (20.51%)

In recent papers he was focusing on the following fields of study:

His primary areas of investigation include Immunology, Microbiology, Ulcerative colitis, Inflammatory bowel disease and Internal medicine. His Immunology research integrates issues from Intestinal mucosa, Gastrointestinal tract, Bifidobacterium and Diarrhea. George T. Macfarlane combines subjects such as Gut flora and Feces with his study of Bifidobacterium.

His work deals with themes such as Bacterial colonization, Lactobacillus acidophilus, Cytokine, Biofilm and Barrett's oesophagus, which intersect with Microbiology. In his research, Crohn's disease and Disease is intimately related to Synbiotics, which falls under the overarching field of Inflammatory bowel disease. His Internal medicine research focuses on Gastroenterology and how it relates to Disease severity.

Between 2007 and 2015, his most popular works were:

  • Bacteria, colonic fermentation, and gastrointestinal health. (458 citations)
  • Fermentation in the human large intestine: its physiologic consequences and the potential contribution of prebiotics. (238 citations)
  • Recommendations for Probiotic Use—2011 Update (177 citations)

In his most recent research, the most cited papers focused on:

  • Internal medicine
  • Enzyme
  • Biochemistry

George T. Macfarlane mainly investigates Immunology, Inflammatory bowel disease, Ulcerative colitis, Synbiotics and Disease. His Immunology research is multidisciplinary, incorporating perspectives in Necrotizing enterocolitis, Intestinal mucosa and Microbiology. His research in Microbiology focuses on subjects like Dysbiosis, which are connected to Biofilm.

The study incorporates disciplines such as Probiotic, Bacteriotherapy, Immune system, Antibiotic-associated diarrhea and Diarrhea in addition to Inflammatory bowel disease. His research integrates issues of Human gastrointestinal tract, Gastrointestinal tract, Mucous membrane and Bifidobacterium in his study of Immune system. His study in Ulcerative colitis is interdisciplinary in nature, drawing from both Antibiotics and Etiology.

Best Publications

  • Short chain fatty acids in human large intestine, portal, hepatic and venous blood.

    J. H. Cummings;E. W. Pomare;W. J. Branch;C. P. E. Naylor

  • Regulation of short-chain fatty acid production

    Sandra Macfarlane;George T. Macfarlane

  • The control and consequences of bacterial fermentation in the human colon.

    J.H. Cummings;G.T. Macfarlane

  • Bacteria, colonic fermentation, and gastrointestinal health.

    George T Macfarlane;Sandra Macfarlane

  • Characterization of Bacterial Communities in Feces from Healthy Elderly Volunteers and Hospitalized Elderly Patients by Using Real-Time PCR and Effects of Antibiotic Treatment on the Fecal Microbiota

    Sabine Bartosch;Alemu Fite;George T. Macfarlane;Marion E. T. McMurdo

  • Synbiotic therapy (Bifidobacterium longum/Synergy 1) initiates resolution of inflammation in patients with active ulcerative colitis: a randomised controlled pilot trial

    Furrie E;Macfarlane S;Kennedy A;Cummings Jh

  • Bacterial metabolism and health-related effects of galacto-oligosaccharides and other prebiotics

    G.T. Macfarlane;H. Steed;S. Macfarlane

  • Comparison of fermentation reactions in different regions of the human colon

    G.T. Macfarlane;Glenn Gibson;J.H. Cummings

  • Prebiotic digestion and fermentation

    John H Cummings;George T Macfarlane;Hans N Englyst

  • Validation of a Three-Stage Compound Continuous Culture System for Investigating the Effect of Retention Time on the Ecology and Metabolism of Bacteria in the Human Colon

    George T. Macfarlane;S. Macfarlane;G.R. Gibson

  • Functional Food Properties of Non-Digestible Oligosaccharides: A Consensus Report From the ENDO Project (DGXII AIRII-CT94-1095)

    J Van Loo;J Cummings;Nathalie M. Delzenne;H Englyst

  • Changes in predominant bacterial populations in human faeces with age and with Clostridium difficile infection.

    M.J. Hopkins;G.T. Macfarlane

  • Protein degradation by human intestinal bacteria.

    G. T. Macfarlane;J. H. Cummings;C. Allison

  • Enumeration of human colonic bacteria producing phenolic and indolic compounds : effects of pH, carbohydrate availability and retention time on dissimilatory aromatic amino acid metabolism

    E.A. Smith;G.T. Macfarlane

  • Comparison of compositions and metabolic activities of fecal microbiotas in young adults and in antibiotic-treated and non-antibiotic-treated elderly subjects

    Emma J. Woodmansey;Marion E. T. McMurdo;George T. Macfarlane;Sandra Macfarlane

  • Fermentation in the human large intestine: its physiologic consequences and the potential contribution of prebiotics.

    George T. Macfarlane;Sandra Macfarlane

  • Probiotics and prebiotics: can regulating the activities of intestinal bacteria benefit health?

    George T Macfarlane;John H Cummings

  • Growth and activities of sulphate-reducing bacteria in gut contents of healthy subjects and patients with ulcerative colitis

    Glenn Gibson;J.H. Cummings;G.T. Macfarlane

  • Gastrointestinal effects of prebiotics

    J. H. Cummings;G. T. Macfarlane

  • Toll-like receptors-2 ,- 3 and -4 expression patterns on human colon and their regulation by mucosal-associated bacteria

    Elizabeth Furrie;Sandra Macfarlane;George Thomson;George T. Macfarlane

  • Role of intestinal bacteria in nutrient metabolism

    J.H. Cummings;G.T. Macfarlane

Frequent Co-Authors

Sandra Macfarlane
Sandra Macfarlane University of Dundee
John H. Cummings
John H. Cummings University of Dundee
Glenn R. Gibson
Glenn R. Gibson University of Reading
Andrew J. McBain
Andrew J. McBain University of Manchester
Mark E. Shirtliff
Mark E. Shirtliff University of Maryland, Baltimore
Miguel Gueimonde
Miguel Gueimonde Spanish National Research Council
Harry J. Flint
Harry J. Flint University of Aberdeen
Alan W. Walker
Alan W. Walker University of Aberdeen
Peter Gilbert
Peter Gilbert University of Manchester
Nathalie M. Delzenne
Nathalie M. Delzenne Université Catholique de Louvain

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