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Molecular Biology

D-Index
97
Citations
30780
World Ranking
597
National Ranking
329

Research.com Recognitions

  • 2013 - Member of the National Academy of Sciences
  • 2000 - Fellow of the American Academy of Arts and Sciences
  • 1947 - Fellow of John Simon Guggenheim Memorial Foundation
  • 1946 - Fellow of John Simon Guggenheim Memorial Foundation

Overview

E. M. De Robertis is affiliated with the University of California, Los Angeles in the United States. Their research primarily focuses on the fields of Biochemistry, Genetics, and Molecular Biology, with a significant emphasis on Molecular Biology and Cell Biology.

The main topics of their work include:

  • Wnt/β-catenin signaling in development and cancer
  • Developmental Biology and Gene Regulation
  • Cancer-related gene regulation
  • Cellular transport and secretion
  • Hedgehog Signaling Pathway Studies
  • Axon Guidance and Neuronal Signaling
  • Hippo pathway signaling and YAP/TAZ

De Robertis has contributed to several frequent publication venues, including:

  • Proceedings of the National Academy of Sciences
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cells and Development
  • Developmental Biology
  • STAR Protocols

The scientist has coauthored numerous papers with notable collaborators such as Nydia Tejeda-Muñoz, Yagmur Azbazdar, Julia Monka, Lauren V. Albrecht, and Gabriele Colozza.

Representative papers authored or coauthored by E. M. De Robertis include:

  • "Cell Biology of Canonical Wnt Signaling" (2021) published in Annual Review of Cell and Developmental Biology
  • "GSK3 Inhibits Macropinocytosis and Lysosomal Activity through the Wnt Destruction Complex Machinery" (2020) published in Cell Reports
  • "Wnt-inducible Lrp6-APEX2 interacting proteins identify ESCRT machinery and Trk-fused gene as components of the Wnt signaling pathway" (2020) published in Scientific Reports
  • "Evo-Devo of Urbilateria and its larval forms" (2022) published in Developmental Biology
  • "Protocol for Probing Regulated Lysosomal Activity and Function in Living Cells" (2020) published in STAR Protocols

Throughout their career, E. M. De Robertis has received recognition including:

  • Member of the National Academy of Sciences (2013)
  • Fellow of the American Academy of Arts and Sciences (2000)
  • Fellow of John Simon Guggenheim Memorial Foundation (1946, 1947)

Best Publications

  • The head inducer Cerberus is a multifunctional antagonist of Nodal, BMP and Wnt signals.

    Stefano Piccolo;Stefano Piccolo;Eric Agius;Luc Leyns;Luc Leyns;Subha Bhattacharyya

  • Connective-tissue growth factor (CTGF) modulates cell signalling by BMP and TGF-beta.

    José G. Abreu;Nan I. Ketpura;Bruno Reversade;E. M. De Robertis

  • A common plan for dorsoventral patterning in Bilateria

    E. M. De Robertis;Yoshiki Sasai

  • Dorsal-ventral patterning and neural induction in Xenopus embryos.

    Edward M. De Robertis;Hiroki Kuroda

  • SUBCELLULAR DISTRIBUTION OF THE ENZYMES OF THE GLUTAMIC ACID, GLUTAMINE AND GAMMA-AMINOBUTYRIC ACID CYCLES IN RAT BRAIN.

    L. Salganicoff;E. De Robertis

  • The organizer factors Chordin and Noggin are required for mouse forebrain development

    Daniel Bachiller;John Klingensmith;C. Kemp;J. A. Belo

  • Endodermal Nodal-related signals and mesoderm induction in Xenopus.

    Eric Agius;Michael Oelgeschläger;Oliver Wessely;Caroline Kemp

  • ISOLATION OF SYNAPTIC VESICLES AND STRUCTURAL ORGANIZATION OF THE ACETYLCHOLINE SYSTEM WITHIN BRAIN NERVE ENDINGS

    E. de Robertis;Georgina Rodriguez de Lores Arnaiz;L. Salganicoff Amanda Pellegrino de Iraldi;L. M. Zieher

  • Integration of IGF, FGF, and anti-BMP signals via Smad1 phosphorylation in neural induction

    Edgar M. Pera;Atsushi Ikeda;Edward Eivers;Eddy M. De Robertis

  • On the function of BMP-4 in patterning the marginal zone of the Xenopus embryo.

    A. Fainsod;H. Steinbeisser;E.M. De Robertis

  • The establishment of spemann's organizer and patterning of the vertebrate embryo

    E. M. De Robertis;J. Larraín;M. Oelgeschläger;Oliver Wessely

  • Tail formation as a continuation of gastrulation: the multiple cell populations of the Xenopus tailbud derive from the late blastopore lip.

    L.K. Gont;H. Steinbeisser;B. Blumberg;E.M. de Robertis

  • Organizer-specific homeobox genes in Xenopus laevis embryos.

    B. Blumberg;C. V. E. Wright;E. M. De Robertis;K. W. Y. Cho

  • Evo-Devo: Variations on Ancestral Themes

    E.M. De Robertis

  • Expression of zebrafish goosecoid and no tail gene products in wild-type and mutant no tail embryos

    S. Schulte-Merker;M. Hammerschmidt;D. Beuchle;K.W. Cho

  • BMP gradients: A paradigm for morphogen-mediated developmental patterning

    Ethan Bier;Edward M. De Robertis

  • Spemann's organizer and self-regulation in amphibian embryos

    Edward M. De Robertis

  • Targeted mutation of the murine goosecoid gene results in craniofacial defects and neonatal death

    G. Yamada;Ahmed Mansouri;M. Torres;E. T. Stuart

  • A spinal cord fate map in the avian embryo: while regressing, Hensen's node lays down the notochord and floor plate thus joining the spinal cord lateral walls.

    M. Catala;M.A. Teillet;E.M. De Robertis;M.L. Le Douarin

  • ZEBRAFISH PARAXIAL PROTOCADHERIN IS A DOWNSTREAM TARGET OF SPADETAIL INVOLVED IN MORPHOGENESIS OF GASTRULA MESODERM

    Akihito Yamamoto;Sharon L. Amacher;Sung-Hyun Kim;Douglas Geissert

Frequent Co-Authors

John B. Gurdon
John B. Gurdon University of Cambridge
Christopher V.E. Wright
Christopher V.E. Wright Vanderbilt University
Bruno Reversade
Bruno Reversade Agency for Science, Technology and Research
Ken W.Y. Cho
Ken W.Y. Cho University of California, Irvine
Guillermo Oliver
Guillermo Oliver Northwestern University
Stefano Piccolo
Stefano Piccolo University of Padua
Martin Blum
Martin Blum University of Hohenheim
Björn Jonson
Björn Jonson Chalmers University of Technology
Iain W. Mattaj
Iain W. Mattaj Human Technopole
Douglas A. Melton
Douglas A. Melton Harvard University

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