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D-Index & Metrics

Biology and Biochemistry

D-Index
55
Citations
10873
World Ranking
15052
National Ranking
55

Overview

Bruno Reversade is affiliated with the Agency for Science, Technology and Research in Singapore. The research work spans biochemistry, genetics, and molecular biology, with additional focus on medicine. Within these broad fields, their subfields of study include molecular biology, genetics, surgery, immunology, and physiology.

The primary topics of Bruno Reversade's research include inflammasome and immune disorders, RNA modifications and cancer, mitochondrial function and pathology, RNA research and splicing, congenital heart defects research, genetics and neurodevelopmental disorders, and ubiquitin and proteasome pathways.

The scientist has contributed to several recent papers, which include the following:

  • Enteroviral 3C protease activates the human NLRP1 inflammasome in airway epithelia, 2020, Science
  • Mitochondrial peptide BRAWNIN is essential for vertebrate respiratory complex III assembly, 2020, Nature Communications
  • Human NLRP1 is a sensor of pathogenic coronavirus 3CL proteases in lung epithelial cells, 2022, Molecular Cell
  • Direct identification of A-to-I editing sites with nanopore native RNA sequencing, 2022, Nature Methods
  • Structural basis for distinct inflammasome complex assembly by human NLRP1 and CARD8, 2021, Nature Communications

Frequent coauthors in Bruno Reversade's publications include Carine Bonnard, Emmanuelle Szenker-Ravi, Byrappa Venkatesh, Nathalie Escande-Beillard, and Aida M. Bertoli-Avella.

Their work has appeared predominantly in specific publication venues, with numerous contributions to:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Nature Genetics
  • The American Journal of Human Genetics
  • American Journal of Medical Genetics Part A

Best Publications

  • Connective-tissue growth factor (CTGF) modulates cell signalling by BMP and TGF-beta.

    José G. Abreu;Nan I. Ketpura;Bruno Reversade;E. M. De Robertis

  • ELABELA: a hormone essential for heart development signals via the apelin receptor

    Serene C. Chng;Lena Ho;Jing Tian;Bruno Reversade;Bruno Reversade

  • Germline NLRP1 Mutations Cause Skin Inflammatory and Cancer Susceptibility Syndromes via Inflammasome Activation

    Franklin L. Zhong;Ons Mamaï;Lorenzo Sborgi;Lobna Boussofara

  • Consanguineous marriages, pearls and perils: Geneva International Consanguinity Workshop Report

    Hanan Hamamy;Stylianos E. Antonarakis;Luigi Luca Cavalli-Sforza;Samia Temtamy

  • Regulation of ADMP and BMP2/4/7 at Opposite Embryonic Poles Generates a Self-Regulating Morphogenetic Field

    Bruno Reversade;E.M. De Robertis

  • Mutations in PYCR1 cause cutis laxa with progeroid features

    Bruno Reversade;Nathalie Escande-Beillard;Aikaterini Dimopoulou;Bjorn Fischer

  • Embryonic dorsal-ventral signaling: secreted frizzled-related proteins as inhibitors of tolloid proteinases.

    Hojoon X. Lee;Andrea L. Ambrosio;Bruno Reversade;E.M. De Robertis

  • Enteroviral 3C protease activates the human NLRP1 inflammasome in airway epithelia.

    Kim S. Robinson;Daniel Eng Thiam Teo;Kai Sen Tan;Gee Ann Toh

  • Human DPP9 represses NLRP1 inflammasome and protects against autoinflammatory diseases via both peptidase activity and FIIND domain binding.

    Franklin L. Zhong;Kim Robinson;Daniel Eng Thiam Teo;Kiat-Yi Tan

  • ELABELA deficiency promotes preeclampsia and cardiovascular malformations in mice.

    Lena Ho;Marie Van Dijk;Sam Tan Jian Chye;Daniel M. Messerschmidt

  • Proteolytic cleavage of Chordin as a switch for the dual activities of Twisted gastrulation in BMP signaling.

    Juan Larraín;Michael Oelgeschläger;Nan I. Ketpura;Bruno Reversade

  • Multiple self-healing squamous epithelioma is caused by a disease-specific spectrum of mutations in TGFBR1

    David R Goudie;Mariella D'Alessandro;Barry Merriman;Hane Lee

  • RSPO2 inhibition of RNF43 and ZNRF3 governs limb development independently of LGR4/5/6

    Emmanuelle Szenker-Ravi;Umut Altunoglu;Marc Leushacke;Célia Bosso-Lefèvre;Célia Bosso-Lefèvre

  • ELABELA Is an Endogenous Growth Factor that Sustains hESC Self-Renewal via the PI3K/AKT Pathway

    Lena Ho;Shawn Y.X. Tan;Sheena Wee;Yixuan Wu

  • Default neural induction: neuralization of dissociated Xenopus cells is mediated by Ras/MAPK activation.

    Hiroki Kuroda;Hiroki Kuroda;Luis Fuentealba;Atsushi Ikeda;Bruno Reversade

  • Depletion of Bmp2, Bmp4, Bmp7 and Spemann organizer signals induces massive brain formation in Xenopus embryos

    Bruno Reversade;Hiroki Kuroda;Hojoon Lee;Ashley Mays

  • Chordin Is Required for the Spemann Organizer Transplantation Phenomenon in Xenopus Embryos

    Michael Oelgeschläger;Hiroki Kuroda;Bruno Reversade;E.M. De Robertis

  • De novo mutations in SMCHD1 cause Bosma arhinia microphthalmia syndrome and abrogate nasal development

    Christopher T. Gordon;Christopher T. Gordon;Shifeng Xue;Gökhan Yigit;Hicham Filali;Hicham Filali;Hicham Filali

  • ELABELA-APJ axis protects from pressure overload heart failure and angiotensin II-induced cardiac damage.

    Teruki Sato;Chitose Sato;Ayumi Kadowaki;Hiroyuki Watanabe

  • Depletion of Bmp2, Bmp4, Bmp7 and Spemann organizer signals induces massive brain formation in Xenopus embryos - eScholarship

    Bruno Reversade;Hiroki Kuroda;Hojoon Lee;Ashley Mays

Frequent Co-Authors

Hülya Kayserili
Hülya Kayserili Koç University
Byrappa Venkatesh
Byrappa Venkatesh Agency for Science, Technology and Research
Stanley F. Nelson
Stanley F. Nelson University of California, Los Angeles
Hane Lee
Hane Lee University of California, Los Angeles
E. M. De Robertis
E. M. De Robertis University of California, Los Angeles
Bernd Wollnik
Bernd Wollnik University of Göttingen
Jeanne Amiel
Jeanne Amiel Université Paris Cité
James M. Murphy
James M. Murphy Walter and Eliza Hall Institute of Medical Research
Marnie E. Blewitt
Marnie E. Blewitt Walter and Eliza Hall Institute of Medical Research
Tania Attié-Bitach
Tania Attié-Bitach Université Paris Cité

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