World's Best Scientists 2026 revealed!
Denise L. Faustman

Denise L. Faustman

Research.com Recognitions

  • 2016 - Fellow, National Academy of Inventors

Best Publications

  • TNF receptor 2 pathway: drug target for autoimmune diseases

    Denise Faustman;Miriam Davis

  • Islet Regeneration During the Reversal of Autoimmune Diabetes in NOD Mice

    Shohta Kodama;Willem Kühtreiber;Satoshi Fujimura;Elizabeth A. Dale

  • Prevention of rejection of murine islet allografts by pretreatment with anti-dendritic cell antibody

    Denise L. Faustman;Ralph M. Steinman;Howard M. Gebel;Vera Hauptfeld

  • Structural principles of tumor necrosis factor superfamily signaling.

    Éva S. Vanamee;Denise L. Faustman

  • Linkage of faulty major histocompatibility complex class I to autoimmune diabetes

    Denise Faustman;Xiangping Li;Herbert Y. Lin;Yineng Fu

  • Reversal of established autoimmune diabetes by restoration of endogenous β cell function

    Shinichiro Ryu;Shohta Kodama;Kazuko Ryu;David A. Schoenfeld

  • Prolongation of murine islet allograft survival by pretreatment of islets with antibody directed to Ia determinants

    Denise Faustman;Vera Hauptfeld;Paul Lacy;Joseph Davie

  • Homogeneous Expansion of Human T-Regulatory Cells Via Tumor Necrosis Factor Receptor 2

    Yoshiaki Okubo;Toshiyuki Mera;Limei Wang;Denise L. Faustman

  • Prevention of xenograft rejection by masking donor HLA class I antigens.

    Denise Faustman;Chuck Coe

  • Targeting TNFR2 with antagonistic antibodies inhibits proliferation of ovarian cancer cells and tumor-associated Tregs.

    Heather Torrey;John Butterworth;Toshiyuki Mera;Yoshiaki Okubo

  • Xenotransplantation of canine, bovine, and porcine islets in diabetic rats without immunosuppression.

    R P Lanza;D H Butler;K M Borland;J E Staruk

  • Proof-of-Concept, Randomized, Controlled Clinical Trial of Bacillus-Calmette-Guerin for Treatment of Long-Term Type 1 Diabetes

    Denise Louise Faustman;Limei Wang;Yoshiaki Okubo;Douglas E. Burger

  • TNF Receptor 2 and Disease: Autoimmunity and Regenerative Medicine.

    Denise Louise Faustman;Miriam Davis

  • Selective death of autoreactive T cells in human diabetes by TNF or TNF receptor 2 agonism

    Liqin Ban;Jack Zhang;Limei Wang;Willem Kuhtreiber

  • TNFR2: A Novel Target for Cancer Immunotherapy.

    Éva S. Vanamee;Denise L. Faustman

  • The therapeutic potential of tumor necrosis factor for autoimmune disease: a mechanistically based hypothesis.

    S. Kodama;M. Davis;D. L. Faustman

  • Long-term reduction in hyperglycemia in advanced type 1 diabetes: the value of induced aerobic glycolysis with BCG vaccinations.

    Willem M. Kühtreiber;Lisa Tran;Taesoo Kim;Michael Dybala

  • Development of Spontaneous Uterine Tumors in Low Molecular Mass Polypeptide-2 Knockout Mice

    Takuma Hayashi;Denise L. Faustman

  • Treg activation defect in type 1 diabetes: correction with TNFR2 agonism.

    Yoshiaki Okubo;Heather Torrey;John Butterworth;Hui Zheng

  • Essential Role of Human Leukocyte Antigen-encoded Proteasome Subunits in NF-κB Activation and Prevention of Tumor Necrosis Factor-α-induced Apoptosis *

    Takuma Hayashi;Denise Faustman

Frequent Co-Authors

Joseph M. Davie
Joseph M. Davie Pfizer (Germany)
Joel F. Habener
Joel F. Habener Harvard University
George S. Eisenbarth
George S. Eisenbarth University of Colorado Denver
Robert Lanza
Robert Lanza Astellas Pharma (Japan)
Joseph Avruch
Joseph Avruch Harvard University
Steven P. Gygi
Steven P. Gygi Harvard University
Anthony P. Monaco
Anthony P. Monaco Tufts University
Donald C. Shreffler
Donald C. Shreffler Washington University in St. Louis
William J. Murphy
William J. Murphy University of California, Davis
Alberto Bianco
Alberto Bianco University of Strasbourg

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