D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Molecular Biology D-index 51 Citations 8,484 145 World Ranking 1746 National Ranking 885

Research.com Recognitions

Awards & Achievements

1982 - Member of the National Academy of Sciences

1980 - Member of the National Academy of Medicine (NAM)

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • DNA

His primary areas of investigation include Antigen, Molecular biology, Gene, Genetics and Immunology. His research on Antigen also deals with topics like

  • Immune system which is related to area like Antibody, Tissue culture and Heterologous,
  • Biochemistry which is related to area like Immune sera. Donald C. Shreffler combines subjects such as Anticorps monoclonal, Monoclonal antibody, In vitro, Antiserum and BALB/c with his study of Molecular biology.

His BALB/c study incorporates themes from C57BL/6 and Histocompatibility. Allele, Major histocompatibility complex and Haplotype are the core of his Gene study. His Human genetics, Mutation and Lp antigen study, which is part of a larger body of work in Genetics, is frequently linked to Control, bridging the gap between disciplines.

His most cited work include:

  • The H-2 major histocompatibility complex and the I immune response region: genetic variation, function, and organization. (676 citations)
  • Genetic control of the immune response. Mapping of the Ir-1 locus. (318 citations)
  • New Lymphocyte Antigen System (Lna) Controlled by the Ir Region of the Mouse H-2 Complex (245 citations)

What are the main themes of his work throughout his whole career to date?

Donald C. Shreffler mainly investigates Molecular biology, Genetics, Gene, Antigen and Immunology. His studies in Molecular biology integrate themes in fields like In vitro, Tissue culture, Biochemistry, Spleen and Antibody. His Antibody research includes themes of Cell and Lymphocyte.

His study on Gene is mostly dedicated to connecting different topics, such as Immune system. The various areas that he examines in his Antigen study include Cytotoxic T cell, T cell and Virology. His Histocompatibility research is multidisciplinary, incorporating perspectives in Epitope, Hemagglutination and Transplantation.

He most often published in these fields:

  • Molecular biology (46.36%)
  • Genetics (34.44%)
  • Gene (34.44%)

What were the highlights of his more recent work (between 1984-2016)?

  • Genetics (34.44%)
  • Molecular biology (46.36%)
  • Gene (34.44%)

In recent papers he was focusing on the following fields of study:

His primary areas of study are Genetics, Molecular biology, Gene, Major histocompatibility complex and Haplotype. His Molecular biology research is multidisciplinary, relying on both Recombinant DNA, Virology, Antigen, Platelet and Antibody. The study incorporates disciplines such as C57BL/6 and Transplantation in addition to Virology.

Donald C. Shreffler works in the field of Antigen, namely Lymphokine. Major histocompatibility complex is a subfield of Immunology that Donald C. Shreffler investigates. Haplotype is the subject of his research, which falls under Allele.

Between 1984 and 2016, his most popular works were:

  • Monoclonal antibodies to mouse antigens. II. Characterization of thirty-one anti-I-J reagents. (148 citations)
  • Studies on Recombination within the Mouse H-2 Complex I.: Three Recombinants Which Position the Ss Locus within the Complex (37 citations)
  • Origin of the fourth component of complement related Chido and Rodgers blood group antigens. (32 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • DNA

Donald C. Shreffler mostly deals with Molecular biology, Genetics, Gene, Recombination and Antigen. His study in the field of Cleavage is also linked to topics like In patient. Congenic and Major histocompatibility complex are subfields of Genetics in which his conducts study.

His work deals with themes such as C57BL/6, Transplantation and Virology, which intersect with Gene. His Recombination research is multidisciplinary, incorporating elements of Hemagglutination tests, Locus, Genetic Crosses, Serology and Inbred strain. His work carried out in the field of Antigen brings together such families of science as Anticorps monoclonal, Antibody, Monoclonal antibody, Platelet and Lymphocyte.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

The H-2 major histocompatibility complex and the I immune response region: genetic variation, function, and organization.

Donald C. Shreffler;Chella S. David.
Advances in Immunology (1975)

1067 Citations

Genetic control of the immune response. Mapping of the Ir-1 locus.

Hugh O. McDevitt;Beverly D. Deak;Donald C. Shreffler;Jan Klein.
Journal of Experimental Medicine (1972)

487 Citations

New Lymphocyte Antigen System (Lna) Controlled by the Ir Region of the Mouse H-2 Complex

C. S. David;Donald C. Shreffler;Jeffrey A. Frelinger.
Proceedings of the National Academy of Sciences of the United States of America (1973)

371 Citations

Evidence for the expression of Ia (H-2-associated) antigens on thymus-derived lymphocytes

Jeffrey A. Frelinger;Jeffrey A. Frelinger;John E. Niederhuber;C. S. David;Donald C. Shreffler.
Journal of Experimental Medicine (1974)

288 Citations

H-2 haplotypes, genes, regions, and antigens: First listing

Jan Klein;Jan Klein;Lorraine Flaherty;John L. VandeBerg;Donald C. Shreffler.
Immunogenetics (1978)

269 Citations

Monoclonal antibodies to mouse antigens. II. Characterization of thirty-one anti-I-J reagents.

Vera Hauptfeld;Judith A. Kapp;Katherine Frederick;JoAnn Trial.
Immunogenetics (1985)

226 Citations

Ir-genes in H-2 regulate generation of anti-viral cytotoxic T cells. Mapping to K or D and dominance of unresponsiveness.

R M Zinkernagel;A Althage;S Cooper;G Kreeb.
Journal of Experimental Medicine (1978)

214 Citations

H-2 restriction of cell-mediated immunity to an intracellular bacterium: effector T cells are specific for Listeria antigen in association with H-21 region-coded self-markers.

R M Zinkernagel;A Althage;B Adler;R V Blanden.
Journal of Experimental Medicine (1977)

167 Citations

Membrane molecules determined by the H-2 associated immune response region: isolation and some properties.

S. E. Cullen;C. S. David;D. C. Shreffler;S. G. Nathenson.
Proceedings of the National Academy of Sciences of the United States of America (1974)

167 Citations

A sex-limited serum protein variant in the mouse: inheritance and association with the H-2 region.

Howard C. Passmore;Donald C. Shreffler.
Biochemical Genetics (1970)

165 Citations

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