World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
110
Citations
48656
World Ranking
5522
National Ranking
2978

Overview

What is he best known for?

The fields of study he is best known for:

  • Internal medicine
  • Gene
  • Disease

D. C. Gajdusek mainly focuses on Virology, Disease, Scrapie, Kuru and Virus. His Virology study combines topics in areas such as Amyloid precursor protein, Familial Creutzfeldt-Jakob, PRNP, Molecular biology and Creutzfeldt-Jakob Syndrome. The concepts of his Disease study are interwoven with issues in Surgery, Viral disease, Saliva, Transmission and Pediatrics.

His Scrapie research incorporates themes from Protein tertiary structure, Protein secondary structure, Crystallography, Titer and Infectivity. His Kuru research includes themes of Gerstmann–Sträussler–Scheinker syndrome, Degenerative disease, Ethnology, Transmissible mink encephalopathy and Neuropathology. His Transmissible mink encephalopathy study incorporates themes from Encephalitis and Dementia.

His most cited work include:

  • Unconventional viruses and the origin and disappearance of kuru. (766 citations)
  • Human Spongiform Encephalopathy: The National Institutes of Health Series of 300 Cases of Experimentally Transmitted Disease (663 citations)
  • Experimental Transmission of a Kuru-like Syndrome to Chimpanzees (658 citations)

What are the main themes of his work throughout his whole career to date?

The scientist’s investigation covers issues in Virology, Pathology, Scrapie, Virus and Disease. His work carried out in the field of Virology brings together such families of science as Antibody, Immunology, Antigen and Kuru. His Kuru study frequently draws connections to other fields, such as Genetics.

His study looks at the relationship between Scrapie and fields such as Amyloid, as well as how they intersect with chemical problems. His work in Virus addresses subjects such as Molecular biology, which are connected to disciplines such as Biochemistry. His Disease study integrates concerns from other disciplines, such as Transmission, Demography, Epidemiology and Pediatrics.

He most often published in these fields:

  • Virology (44.33%)
  • Pathology (28.18%)
  • Scrapie (23.71%)

What were the highlights of his more recent work (between 1989-2007)?

  • Pathology (28.18%)
  • Virology (44.33%)
  • Scrapie (23.71%)

In recent papers he was focusing on the following fields of study:

D. C. Gajdusek spends much of his time researching Pathology, Virology, Scrapie, Disease and Genetics. His Pathology study combines topics in areas such as Viral disease and Myelin. Virus is the focus of his Virology research.

His Scrapie research integrates issues from Bovine spongiform encephalopathy, Slow virus, Infectivity, Amyloid and Hamster. In general Disease, his work in Progressive dementia is often linked to Short duration linking many areas of study. His research integrates issues of Transmissible spongiform encephalopathy and Gerstmann–Sträussler–Scheinker syndrome in his study of Kuru.

Between 1989 and 2007, his most popular works were:

  • Human Spongiform Encephalopathy: The National Institutes of Health Series of 300 Cases of Experimentally Transmitted Disease (663 citations)
  • Conformational transitions, dissociation, and unfolding of scrapie amyloid (prion) protein. (340 citations)
  • Transmissible familial Creutzfeldt-Jakob disease associated with five, seven, and eight extra octapeptide coding repeats in the PRNP gene (289 citations)

In his most recent research, the most cited papers focused on:

  • Internal medicine
  • Gene
  • Virus

His primary areas of study are Scrapie, Virology, Pathology, Genetics and Infectivity. The various areas that he examines in his Scrapie study include Molecular biology, Hamster, Protein secondary structure, Crystallography and Amyloid. He studies Virology, focusing on Virus in particular.

His studies deal with areas such as Nucleic acid sequence and Genetic variation as well as Virus. As a member of one scientific family, D. C. Gajdusek mostly works in the field of Pathology, focusing on Viral disease and, on occasion, Disease, Formic acid and Tissue Preservation. The Infectivity study combines topics in areas such as Bovine spongiform encephalopathy and Formaldehyde.

Best Publications

  • Characterization and chromosomal localization of a cDNA encoding brain amyloid of Alzheimer's disease

    D Goldgaber;MI Lerman;OW McBride;U Saffiotti

  • Unconventional viruses and the origin and disappearance of kuru.

    DC Gajdusek

  • HTLV-III infection in brains of children and adults with AIDS encephalopathy

    George M. Shaw;Mary E. Harper;Beatrice H. Hahn;Leon G. Epstein

  • Human spongiform encephalopathy: the National Institutes of Health series of 300 cases of experimentally transmitted disease

    Brown P;Gibbs Cj;Rodgers-Johnson P;Asher Dm

  • Experimental Transmission of a Kuru-like Syndrome to Chimpanzees

    D C Gajdusek;C J Gibbs;M Alpers

  • Creutzfeldt-Jakob Disease (Spongiform Encephalopathy): Transmission to the Chimpanzee

    C. J. Gibbs;D. C. Gajdusek;D. M. Asher;M. P. Alpers

  • Intraneuronal aluminum accumulation in amyotrophic lateral sclerosis and Parkinsonism-dementia of Guam.

    DP Perl;DC Gajdusek;RM Garruto;RT Yanagihara

  • Creutzfeldt‐Jakob disease: Patterns of worldwide occurrence and the significance of familial and sporadic clustering

    Masters Cl;Harris Jo;Gajdusek Dc;Gibbs Cj

  • Human immunodeficiency virus type 1 neutralization epitope with conserved architecture elicits early type-specific antibodies in experimentally infected chimpanzees

    J Goudsmit;C Debouck;R H Meloen;L Smit

  • Interleukin 1 regulates synthesis of amyloid beta-protein precursor mRNA in human endothelial cells.

    D Goldgaber;H W Harris;T Hla;T Maciag

  • Creutzfeldt-Jakob disease virus isolations from the Gerstmann-Sträussler syndrome with an analysis of the various forms of amyloid plaque deposition in the virus-induced spongiform encephalopathies.

    Masters Cl;Gajdusek Dc;Gibbs Cj

  • Degenerative disease of the central nervous system in New Guinea; the endemic occurrence of kuru in the native population.

    D. C. Gajdusek;V. Zigas

  • DANGER OF ACCIDENTAL PERSON-TO-PERSON TRANSMISSION OF CREUTZFELDT-JAKOB DISEASE BY SURGERY

    C. Bernoulli;J. Siegfried;G. Baumgartner;F. Regli

  • Infection of chimpanzees by human T-lymphotropic retroviruses in brain and other tissues from AIDS patients.

    D. Carleton Gajdusek;Clarence J. Gibbs;Pamela Rodgers-Johnson;Herbert L. Amyx

  • Conformational transitions, dissociation, and unfolding of scrapie amyloid (prion) protein.

    J Safar;P P Roller;D C Gajdusek;C J Gibbs

  • Creutzfeldt-Jakob disease: clinical analysis of a consecutive series of 230 neuropathologically verified cases.

    Brown P;Cathala F;Castaigne P;Gajdusek Dc

  • Transmissible familial Creutzfeldt-Jakob disease associated with five, seven, and eight extra octapeptide coding repeats in the PRNP gene

    L G Goldfarb;P Brown;W R McCombie;D Goldgaber

  • The epidemiology of Creutzfeldt-Jakob disease: conclusion of a 15-year investigation in France and review of the world literature

    P Brown;F Cathala;RF Raubertas;DC Gajdusek

  • Pathology of Kuru.

    I Klatzo;D C Gajdusek;V Zigas

  • Creutzfeldt-Jakob Disease

    Elisabeth Beck;P. M. Daniel;W. B. Matthews;D. L. Stevens

Frequent Co-Authors

C. J. Gibbs
C. J. Gibbs National Institutes of Health
Richard Yanagihara
Richard Yanagihara University of Hawaii at Manoa
Michael P. Alpers
Michael P. Alpers Curtin University
Paul Brown
Paul Brown National Institutes of Health
Jaap Goudsmit
Jaap Goudsmit Harvard University
Lev G. Goldfarb
Lev G. Goldfarb National Institutes of Health
Pedro Piccardo
Pedro Piccardo University of Edinburgh
John J. Hooks
John J. Hooks National Institutes of Health
Raymond P. Roos
Raymond P. Roos University of Chicago
Leon G. Epstein
Leon G. Epstein Northwestern University

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Best Scientists Citing D. C. Gajdusek