Brian G. Pierce

Best Publications

• Updates to the Integrated Protein-Protein Interaction Benchmarks: Docking Benchmark Version 5 and Affinity Benchmark Version 2.

  Thom Vreven;Iain H. Moal;Anna Vangone;Brian G. Pierce

  480
  Citations

• Benchmarking AlphaFold for protein complex modeling reveals accuracy determinants

  Unknown

  441
  Citations

• Protein-Protein Docking Benchmark 2.0: an update.

  Julian Mintseris;Kevin Wiehe;Brian Pierce;Robert Anderson

  374
  Citations

• An expanded benchmark for antibody-antigen docking and affinity prediction reveals insights into antibody recognition determinants.

  Johnathan D. Guest;Thom Vreven;Jing Zhou;Iain Moal

  132
  Citations

• TCR3d: The T cell receptor structural repertoire database.

  Unknown

  114
  Citations

• Evaluation of <scp>AlphaFold</scp> antibody–antigen modeling with implications for improving predictive accuracy

  Unknown

  108
  Citations

• Structure-based design of a T-cell receptor leads to nearly 100-fold improvement in binding affinity for pepMHC.

  Jaafar N. Haidar;Brian G. Pierce;Yong Yu;Weiwei Tong

  101
  Citations

• Cutting Edge: Evidence for a Dynamically Driven T Cell Signaling Mechanism

  William F. Hawse;Matthew M. Champion;Michelle V. Joyce;Lance M. Hellman

  101
  Citations

• Computational Design of the Affinity and Specificity of a Therapeutic T Cell Receptor

  Brian G. Pierce;Lance M. Hellman;Moushumi Hossain;Nishant K. Singh

  99
  Citations

• A flexible docking approach for prediction of T cell receptor–peptide–MHC complexes

  Brian G. Pierce;Zhiping Weng

  95
  Citations

• Global mapping of antibody recognition of the hepatitis C virus E2 glycoprotein: Implications for vaccine design.

  Brian G Pierce;Zhen-Yong Keck;Patrick Lau;Catherine Fauvelle;Catherine Fauvelle

  94
  Citations

• TCRmodel2: high-resolution modeling of T cell receptor recognition using deep learning

  Unknown

  86
  Citations

• Cellular origins and genetic landscape of cutaneous gamma delta T cell lymphomas.

  Unknown

  86
  Citations

• CoV3D: a database of high resolution coronavirus protein structures.

  Ragul Gowthaman;Johnathan D Guest;Rui Yin;Jared Adolf-Bryfogle

  80
  Citations

• ATLAS: A database linking binding affinities with structures for wild-type and mutant TCR-pMHC complexes

  Tyler M. Borrman;Jennifer M. Cimons;Michael Cosiano;Michael Purcaro

  79
  Citations

• Structural Basis for Penetration of the Glycan Shield of Hepatitis C Virus E2 Glycoprotein by a Broadly Neutralizing Human Antibody

  Yili Li;Brian G. Pierce;Qian Wang;Zhen-Yong Keck

  77
  Citations

• Blind prediction of interfacial water positions in CAPRI

  Marc F. Lensink;Iain H. Moal;Iain H. Moal;Paul A. Bates;Panagiotis L. Kastritis

  75
  Citations

• Antigenicity and Immunogenicity of Differentially Glycosylated Hepatitis C Virus E2 Envelope Proteins Expressed in Mammalian and Insect Cells.

  Richard A. Urbanowicz;Richard A. Urbanowicz;Ruixue Wang;John E. Schiel;Zhen-yong Keck

  75
  Citations

• Affinity maturation of a broadly neutralizing human monoclonal antibody that prevents acute hepatitis C virus infection in mice.

  Zhen Yong Keck;Yong Wang;Patrick Lau;Garry Lund

  74
  Citations

• Structural basis for oligoclonal T cell recognition of a shared p53 cancer neoantigen.

  Daichao Wu;Daichao Wu;D. Travis Gallagher;D. Travis Gallagher;Ragul Gowthaman;Brian G. Pierce

  72
  Citations